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Invitrogen
CD300g Polyclonal Antibody
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CD300g Antibody (PA5-47755) in WB
Western blot analysis of CD300g in mouse kidney tissue. Samples were incubated in CD300g polyclonal antibody (Product # PA5-47755) using a dilution of 1 µg/mL followed by a HRP-conjugated Anti-Sheep IgG secondary antibody. A specific band was detected for CD300g/Nepmucin at approximately 60 kDa (as indicated). This experiment was conducted under reducing conditions.
产品信息
PA5-47755
产品规格
种属反应
Mouse
宿主/亚型
Sheep
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Mouse myeloma cell line NS0-derived recombinant mouse CD300g/Nepmucin Leu19-Ile284
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
In direct ELISAs, less than 1% cross-reactivity with recombinant human CD300g/Nepmucin is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
CD300g, also known as Immunoglobulin-like Transcripts 4 (ILT4) or CMRF35-like molecule 1 (CLM-1), is a gene located on chromosome 17q25.1, encoding a member of the CD300 family of molecules involved in modulating immune responses. CD300g is expressed on myeloid cells, particularly macrophages and dendritic cells, and plays a role in regulating cell activation and inflammatory processes. It functions as an inhibitory receptor, interacting with phosphatidylserine and other lipid ligands to modulate immune cell activity, influencing cytokine production and phagocytosis. The expression and signaling pathways of CD300g contribute to immune homeostasis and are of particular interest in contexts like autoimmune diseases, infection, and cancer, where immune regulation is disrupted. Research into CD300g aims to uncover potential therapeutic applications in modulating immune functions and offers insights into its role in balancing immune responses in health and disease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD300 antigen-like family member G; CD300g; CD300g antigen; CLM-9; CLM9Trem4; CMRF-35-like molecule-9; CMRF35-like molecule 9; Nepmucin
基因别名: 2310016B05Rik; Cd300lg; Clm9; D11Ertd736e
UniProt ID: (Mouse) Q1ERP8
Entrez Gene ID: (Mouse) 52685
