This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants.
蛋白别名: CD32; CD32 receptor 2; CD32 receptor 2a; CD32 receptor 2b; CD32A; CDw32; Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32); Fc gamma receptor IIb; Fc gamma RIIb; fc-gamma RII-a; Fc-gamma RII-b; fc-gamma-RIIa; Fc-gamma-RIIb; FcGR; FCGR2A1; fcRII-a; fcRII-b; FGFR2B; IgG Fc receptor II-b; Low affinity immunoglobulin gamma Fc region receptor II-b
基因别名: CD32; CD32B; FCG2; FCGR2; FCGR2B; IGFR2
UniProt ID: (Human) P31994
Entrez Gene ID: (Human) 2213
分子生物学功能: immunoglobulin receptor superfamily