Product References
Low Expression of Lipoic Acid Synthase Aggravates Silica-Induced Pulmonary Fibrosis by Inhibiting the Differentiation of Tregs in Mice.
Antioxidants & redox signaling
Yan S,Zhao Y,Yan J,Guan Y,Lyu M,Xu G,Yang X,Bai Y,Yao S
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Thu Aug 01 00:00:00 UTC 2024
Synovial microenvironment-influenced mast cells promote the progression of rheumatoid arthritis.
Nature communications
Lei Y,Guo X,Luo Y,Niu X,Xi Y,Xiao L,He D,Bian Y,Zhang Y,Wang L,Peng X,Wang Z,Chen G
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Jan 02 00:00:00 UTC 2024
Effects of iodine intake on gut microbiota and gut metabolites in Hashimoto thyroiditis-diseased humans and mice.
Communications biology
Gong B,Meng F,Wang X,Han Y,Yang W,Wang C,Shan Z
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Mon Jan 29 00:00:00 UTC 2024
miR-539-5p targets BMP2 to regulate Treg activation in B-cell acute lymphoblastic leukemia through TGF-β/Smads/MAPK.
Experimental biology and medicine (Maywood, N.J.)
Dai Q,Shi R,Zhang G,Wang Y,Ye L,Peng L,Guo S,He J,Yang H,Jiang Y
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Fri Mar 22 00:00:00 UTC 2024
Small Extracellular Vesicles Derived from Altered Peptide Ligand-Loaded Dendritic Cell Act as A Therapeutic Vaccine for Spinal Cord Injury Through Eliciting CD4+ T cell-Mediated Neuroprotective Immunity.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Wang S,Li G,Liang X,Wu Z,Chen C,Zhang F,Niu J,Li X,Yan J,Wang N,Li J,Wang Y
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Mon Jan 01 00:00:00 UTC 2024
AXL inhibition suppresses early allograft monocyte-to-macrophage differentiation and prolongs allograft survival.
JCI insight
Jordan CZ,Tunbridge M,Husain I,Kitai H,Dilts ME,Fay OK,Abe K,Xiang C,Kwun J,Souma T,Thorp EB,Luo X
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Fri Mar 08 00:00:00 UTC 2024
Dubosiella newyorkensis modulates immune tolerance in colitis via the L-lysine-activated AhR-IDO1-Kyn pathway.
Nature communications
Zhang Y,Tu S,Ji X,Wu J,Meng J,Gao J,Shao X,Shi S,Wang G,Qiu J,Zhang Z,Hua C,Zhang Z,Chen S,Zhang L,Zhu SJ
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Feb 13 00:00:00 UTC 2024
Fasudil-modified macrophages reduce inflammation and regulate the immune response in experimental autoimmune encephalomyelitis.
Neural regeneration research
Liu C,Guo S,Liu R,Guo M,Wang Q,Chai Z,Xiao B,Ma C
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Fri Mar 01 00:00:00 UTC 2024
Treatment with glatiramer acetate in APPswe/PS1dE9 mice at an early stage of Alzheimer's disease prior to amyloid-beta deposition delays the disease's pathological development and ameliorates cognitive decline.
Frontiers in aging neuroscience
Huang Z,Gong Z,Lin Y,Yang F,Chen W,Xiang S,Huang Y,Xiao H,Xu S,Duan J
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Thu Feb 15 00:00:00 UTC 2024
YAP/STAT3 inhibited CD8+ T cells activity in the breast cancer immune microenvironment by inducing M2 polarization of tumor-associated macrophages.
Cancer medicine
Wang C,Shen N,Guo Q,Tan X,He S
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Aug 01 00:00:00 UTC 2023
B cell extracellular vesicles contain monomeric IgM that binds antigen and enters target cells.
iScience
Gutknecht MF,Holodick NE,Rothstein TL
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Fri Sep 15 00:00:00 UTC 2023
Selective neuroimmune modulation by type I interferon drives neuropathology and neurologic dysfunction following traumatic brain injury.
Acta neuropathologica communications
Todd BP,Luo Z,Gilkes N,Chimenti MS,Peterson Z,Mix MR,Harty JT,Nickl-Jockschat T,Ferguson PJ,Bassuk AG,Newell EA
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Fri Aug 18 00:00:00 UTC 2023
An essential role for miR-15/16 in Treg suppression and restriction of proliferation.
Cell reports
Johansson K,Gagnon JD,Zhou SK,Fassett MS,Schroeder AW,Kageyama R,Bautista RA,Pham H,Woodruff PG,Ansel KM
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Oct 31 00:00:00 UTC 2023
Subconjunctival injection of human umbilical cord mesenchymal stem cells alleviates experimental allergic conjunctivitis via regulating T cell response.
Stem cell research & therapy
Li D,Ou Q,Shen Q,Lu MM,Xu JY,Jin C,Gao F,Wang J,Zhang J,Zhang J,Li J,Lu L,Xu GT,Tian H
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Mon Oct 02 00:00:00 UTC 2023
Tumor-secreted IFI35 promotes proliferation and cytotoxic activity of CD8+ T cells through PI3K/AKT/mTOR signaling pathway in colorectal cancer.
Journal of biomedical science
Li P,Zhou D,Chen D,Cheng Y,Chen Y,Lin Z,Zhang X,Huang Z,Cai J,Huang W,Lin Y,Ke H,Long J,Zou Y,Ye S,Lan P
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Wed Jun 28 00:00:00 UTC 2023
Respiratory mucosal vaccination of peptide-poloxamine-DNA nanoparticles provides complete protection against lethal SARS-CoV-2 challenge.
Biomaterials
Sun S,Li E,Zhao G,Tang J,Zuo Q,Cai L,Xu C,Sui C,Ou Y,Liu C,Li H,Ding Y,Li C,Lu D,Zhang W,Luo P,Cheng P,Gao Y,Tu C,Pitard B,Rosenecker J,Wang B,Liu Y,Zou Q,Guan S
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Sun Jan 01 00:00:00 UTC 2023
CD138 promotes the accumulation and activation of autoreactive T cells in autoimmune MRL/lpr mice.
Experimental and therapeutic medicine
Xie T,Liu X,Li P
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Fri Dec 01 00:00:00 UTC 2023
HSF1 promotes CD69+ Treg differentiation to inhibit colitis progression.
Theranostics
Yu L,Zhou B,Zhu Y,Li L,Zhong Y,Zhu L,Wang H,Chen H,Xu J,Guo T,Feng L,Wang X,Cai Z,Wang J,Jin H
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Apr 18 00:00:00 UTC 2023
LAMP2 regulates autophagy in the thymic epithelium and thymic stroma-dependent CD4 T cell development.
Autophagy
Rodrigues PM,Sousa LG,Perrod C,Maceiras AR,Ferreirinha P,Pombinho R,Romera-Cárdenas G,Gomez-Lazaro M,Senkara M,Pistolic J,Cabanes D,Klein L,Saftig P,Alves NL
12-0041-82 was used in Flow Cytometry to suggest that LAMP2 interconnects the autophagy-lysosomal axis and the processing of selecting self-peptides:MHC II complexes in cTECs, underling its implications for the generation of a broad CD4 TCR repertoire.
Wed Feb 01 00:00:00 UTC 2023
Prolidase Deficiency Causes Spontaneous T Cell Activation and Lupus-like Autoimmunity.
Journal of immunology (Baltimore, Md. : 1950)
Hodgson R,Crockford TL,Bhandari A,Kepple JD,Back J,Cawthorne E,Abeler-Dörner L,Laing AG,Clare S,Speak A,Adams DJ,Dougan G,Hayday AC,Deobagkar-Lele M,Cornall RJ,Bull KR
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Wed Mar 01 00:00:00 UTC 2023
A candidate subunit vaccine induces protective immunity against Mycobacterium avium subspecies paratuberculosis in mice.
NPJ vaccines
Shao M,Cui N,Tang Y,Chen F,Cui Y,Dang G,Liu S
12-0041-82 was used in ELISA to demonstrate that recombinant protein 66NC is an efficient candidate for further development into a protective vaccine in terms of inducing specific protection against MAP.
Sat May 20 00:00:00 UTC 2023
Radiotherapy combined with anti-CEACAM1 immunotherapy to induce survival advantage in glioma.
Discover oncology
Li J,Chen Y,Fan Y,Wang H,Mu W,Liu X
12-0041-82 was used in Flow Cytometry to show the effect of radiotherapy on the expression of immune checkpoint molecule CEACAM1 in patients with glioma and the therapeutical effect of radiotherapy combined with blockade of CEACAM1 in mice with intracranial gliomas.
Thu Mar 16 00:00:00 UTC 2023
Development of a Syrian hamster anti-PD-L1 monoclonal antibody enables oncolytic adenoviral immunotherapy modelling in an immunocompetent virus replication permissive setting.
Frontiers in immunology
Clubb JHA,Kudling TV,Girych M,Haybout L,Pakola S,Hamdan F,Cervera-Carrascon V,Hemmes A,Grönberg-Vähä-Koskela S,Santos JM,Quixabeira DCA,Basnet S,Heiniö C,Arias V,Jirovec E,Kaptan S,Havunen R,Sorsa S,Erikat A,Schwartz J,Anttila M,Aro K,Viitala T,Vattulainen I,Cerullo V,Kanerva A,Hemminki A
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Mon Feb 27 00:00:00 UTC 2023
TCR repertoire landscape reveals macrophage-mediated clone deletion in endotoxin tolerance.
Inflammation research : official journal of the European Histamine Research Society ... [et al.]
Zhao J,Jia L,Tao Y,Zhao X,Yang J,Lu Y,Yan Y,Mao L,Hu L,Lu J,Guo M,Chen C,Zhou Y,Wen Z,He Z,Xu L
12-0041-82 was used in Flow cytometry/Cell sorting to suggest that the clone selection in thymus in Endotoxin tolerance may confer protection against microbial sepsis.
Wed Mar 01 00:00:00 UTC 2023
GH18 family glycoside hydrolase Chitinase A of Salmonella enhances virulence by facilitating invasion and modulating host immune responses.
PLoS pathogens
Chandra K,Roy Chowdhury A,Chatterjee R,Chakravortty D
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Fri Apr 01 00:00:00 UTC 2022
Rotenone aggravates PD-like pathology in A53T mutant human α-synuclein transgenic mice in an age-dependent manner.
Frontiers in aging neuroscience
Chen AD,Cao JX,Chen HC,Du HL,Xi XX,Sun J,Yin J,Jing YH,Gao LP
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Fri Aug 26 00:00:00 UTC 2022
IL-33 Deficiency Attenuates Lung Inflammation by Inducing Th17 Response and Impacting the Th17/Treg Balance in LPS-Induced ARDS Mice via Dendritic Cells.
Journal of immunology research
Cheng L,Jiao Y,Jiang W,Zhang X,Zhang L,Jia G
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Dec 27 00:00:00 UTC 2022
Interferon-γ Stimulates Interleukin-27 Derived from Dendritic Cells to Regulate Th9 Differentiation through STAT1/3 Pathway.
Disease markers
Xiong P,Liu T,Chen Y,Xu Q,Hu X,Han F,Shi L
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Mon Oct 31 00:00:00 UTC 2022
CD4+ CTLs Act as a Key Effector Population for Allograft Rejection of MSCs in a Donor MHC-II Dependent Manner in Injured Liver.
Aging and disease
Shen S,Li Y,Jin M,Fan D,Pan R,Lin A,Chen Y,Xiang L,Zhao RC,Shao J
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Thu Dec 01 00:00:00 UTC 2022
CD4+ CTLs Act as a Key Effector Population for Allograft Rejection of MSCs in a Donor MHC-II Dependent Manner in Injured Liver.
Aging and disease
Shen S,Li Y,Jin M,Fan D,Pan R,Lin A,Chen Y,Xiang L,Zhao RC,Shao J
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Thu Dec 01 00:00:00 UTC 2022
Free Fatty Acid Receptor 4 (FFA4) Activation Ameliorates Imiquimod-Induced Psoriasis in Mice.
International journal of molecular sciences
Son SE,Koh JM,Im DS
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Apr 19 00:00:00 UTC 2022
Valosin-containing protein (VCP/p97) inhibition reduces viral clearance and induces toxicity associated with muscular damage.
Cell death & disease
Del Rio Oliva M,Basler M
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Thu Dec 01 00:00:00 UTC 2022
Exenatide regulates Th17/Treg balance via PI3K/Akt/FoxO1 pathway in db/db mice.
Molecular medicine (Cambridge, Mass.)
Xu Q,Zhang X,Li T,Shao S
12-0041-82 was used in Flow cytometry/Cell sorting to illustrate that exenatide restores systemic Th17/Treg balance via regulating FoxO1 pathway with the progression of diabetes in db/db mice.
Sat Dec 03 00:00:00 UTC 2022
Ribosome-Targeting Antibiotics Impair T Cell Effector Function and Ameliorate Autoimmunity by Blocking Mitochondrial Protein Synthesis.
Immunity
Almeida L,Dhillon-LaBrooy A,Castro CN,Adossa N,Carriche GM,Guderian M,Lippens S,Dennerlein S,Hesse C,Lambrecht BN,Berod L,Schauser L,Blazar BR,Kalesse M,Müller R,Moita LF,Sparwasser T
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Jan 12 00:00:00 UTC 2021
Cell-mimicking nanodecoys neutralize SARS-CoV-2 and mitigate lung injury in a non-human primate model of COVID-19.
Nature nanotechnology
Li Z,Wang Z,Dinh PC,Zhu D,Popowski KD,Lutz H,Hu S,Lewis MG,Cook A,Andersen H,Greenhouse J,Pessaint L,Lobo LJ,Cheng K
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Immunocytochemistry
Sun Aug 01 00:00:00 UTC 2021
Cell-mimicking nanodecoys neutralize SARS-CoV-2 and mitigate lung injury in a non-human primate model of COVID-19.
Nature nanotechnology
Li Z,Wang Z,Dinh PC,Zhu D,Popowski KD,Lutz H,Hu S,Lewis MG,Cook A,Andersen H,Greenhouse J,Pessaint L,Lobo LJ,Cheng K
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Immunocytochemistry
Sun Aug 01 00:00:00 UTC 2021
NF-κB-inducing kinase maintains T cell metabolic fitness in antitumor immunity.
Nature immunology
Gu M,Zhou X,Sohn JH,Zhu L,Jie Z,Yang JY,Zheng X,Xie X,Yang J,Shi Y,Brightbill HD,Kim JB,Wang J,Cheng X,Sun SC
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Mon Feb 01 00:00:00 UTC 2021
Porphyromonas gingivalis exacerbates ulcerative colitis via Porphyromonas gingivalis peptidylarginine deiminase.
International journal of oral science
Zhao X,Liu J,Zhang C,Yu N,Lu Z,Zhang S,Li Y,Li Q,Liu J,Liu D,Pan Y
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Thu Sep 30 00:00:00 UTC 2021
Uncovering a novel role of PLCβ4 in selectively mediating TCR signaling in CD8+ but not CD4+ T cells.
The Journal of experimental medicine
Sasai M,Ma JS,Okamoto M,Nishino K,Nagaoka H,Takashima E,Pradipta A,Lee Y,Kosako H,Suh PG,Yamamoto M
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Mon Jul 05 00:00:00 UTC 2021
High Ambient Temperature Aggravates Experimental Autoimmune Uveitis Symptoms.
Frontiers in cell and developmental biology
Pan S,Tan H,Chang R,Wang Q,Zhu Y,Chen L,Li H,Su G,Zhou C,Cao Q,Kijlstra A,Yang P
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Apr 13 00:00:00 UTC 2021
Dynamic changes in the systemic immune responses of spinal cord injury model mice.
Neural regeneration research
Gao TY,Huang FF,Xie YY,Wang WQ,Wang LD,Mu D,Cui Y,Wang B
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Mon Feb 01 00:00:00 UTC 2021
Generation of a Novel Oncolytic Vaccinia Virus Using the IHD-W Strain.
Human gene therapy
Shin J,Hong SO,Kim M,Lee H,Choi H,Kim J,Hong J,Kang H,Lee E,Lee S,Kong B,Kim M,Choi H,Kim S
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Sat May 01 00:00:00 UTC 2021
CXCR3 alleviates renal ischemia‑reperfusion injury via increase of Tregs.
Molecular medicine reports
Xian W,Wu J,Li Q,Du X,Wang N,Chen D,Gao W,Cao J
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Thu Jul 01 00:00:00 UTC 2021
Irradiated whole-cell vaccine suppresses hepatocellular carcinoma growth in mice via Th9 cells.
Oncology letters
Chen J,Ding Y,Huang F,Lan R,Wang Z,Huang W,Chen R,Wu B,Fu L,Yang Y,Liu J,Hong J,Zhang W,Zhang L
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Sat May 01 00:00:00 UTC 2021
Preliminary analysis of immunoregulatory mechanism of hyperhomocysteinemia-induced brain injury in Wistar-Kyoto rats.
Experimental and therapeutic medicine
Zhang Y,Wang L,Li X,Geng J
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Sat May 01 00:00:00 UTC 2021
Estrogen receptor beta signaling in CD8+ T cells boosts T cell receptor activation and antitumor immunity through a phosphotyrosine switch.
Journal for immunotherapy of cancer
Yuan B,Clark CA,Wu B,Yang J,Drerup JM,Li T,Jin VX,Hu Y,Curiel TJ,Li R
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Fri Jan 01 00:00:00 UTC 2021
Neuroimmune Consequences of eIF4E Phosphorylation on Chemotherapy-Induced Peripheral Neuropathy.
Frontiers in immunology
Agalave NM,Mody PH,Szabo-Pardi TA,Jeong HS,Burton MD
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Mon Sep 20 00:00:00 UTC 2021
Alphavirus-Driven Interferon Gamma (IFNg) Expression Inhibits Tumor Growth in Orthotopic 4T1 Breast Cancer Model.
Vaccines
Trofimova O,Korotkaja K,Skrastina D,Jansons J,Spunde K,Isaguliants M,Zajakina A
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Wed Oct 27 00:00:00 UTC 2021
A lymph node-targeted Amphiphile vaccine induces potent cellular and humoral immunity to SARS-CoV-2.
Science advances
Steinbuck MP,Seenappa LM,Jakubowski A,McNeil LK,Haqq CM,DeMuth PC
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Mon Feb 01 00:00:00 UTC 2021
IDO1 Expression in Ovarian Cancer Induces PD-1 in T Cells via Aryl Hydrocarbon Receptor Activation.
Frontiers in immunology
Amobi-McCloud A,Muthuswamy R,Battaglia S,Yu H,Liu T,Wang J,Putluri V,Singh PK,Qian F,Huang RY,Putluri N,Tsuji T,Lugade AA,Liu S,Odunsi K
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Fri Oct 29 00:00:00 UTC 2021
Mesenchymal stem cell exosome-derived miR-223 alleviates acute graft-versus-host disease via reducing the migration of donor T cells.
Stem cell research & therapy
Liu W,Zhou N,Liu Y,Zhang W,Li X,Wang Y,Zheng R,Zhang Y
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Fri Feb 26 00:00:00 UTC 2021
Mesenchymal stem cell exosome-derived miR-223 alleviates acute graft-versus-host disease via reducing the migration of donor T cells.
Stem cell research & therapy
Liu W,Zhou N,Liu Y,Zhang W,Li X,Wang Y,Zheng R,Zhang Y
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Fri Feb 26 00:00:00 UTC 2021
G-MDSCs promote aging-related cardiac fibrosis by activating myofibroblasts and preventing senescence.
Cell death & disease
Sun SN,Ni SH,Li Y,Liu X,Deng JP,Chen ZX,Li H,Feng WJ,Huang YS,Li DN,Xian SX,Yang ZQ,Wang LJ,Lu L
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Jun 08 00:00:00 UTC 2021
Butyrate Improves Skin/Lung Fibrosis and Intestinal Dysbiosis in Bleomycin-Induced Mouse Models.
International journal of molecular sciences
Park HJ,Jeong OY,Chun SH,Cheon YH,Kim M,Kim S,Lee SI
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Mar 09 00:00:00 UTC 2021
Mapping Rora expression in resting and activated CD4+ T cells.
PloS one
Haim-Vilmovsky L,Henriksson J,Walker JA,Miao Z,Natan E,Kar G,Clare S,Barlow JL,Charidemou E,Mamanova L,Chen X,Proserpio V,Pramanik J,Woodhouse S,Protasio AV,Efremova M,Griffin JL,Berriman M,Dougan G,Fisher J,Marioni JC,McKenzie ANJ,Teichmann SA
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Fri Nov 12 00:00:00 UTC 2021
Type 2 diabetic mice enter a state of spontaneous hibernation-like suspended animation following accumulation of uric acid.
The Journal of biological chemistry
Zhao Y,Cheng R,Zhao Y,Ge W,Yang Y,Ding Z,Xu X,Wang Z,Wu Z,Zhang J
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Fri Oct 01 00:00:00 UTC 2021
Targeting Ovarian Carcinoma with TSP-1:CD47 Antagonist TAX2 Activates Anti-Tumor Immunity.
Cancers
Jeanne A,Sarazin T,Charlé M,Moali C,Fichel C,Boulagnon-Rombi C,Callewaert M,Andry MC,Diesis E,Delolme F,Rioult D,Dedieu S
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Thu Oct 07 00:00:00 UTC 2021
Targeting Ovarian Carcinoma with TSP-1:CD47 Antagonist TAX2 Activates Anti-Tumor Immunity.
Cancers
Jeanne A,Sarazin T,Charlé M,Moali C,Fichel C,Boulagnon-Rombi C,Callewaert M,Andry MC,Diesis E,Delolme F,Rioult D,Dedieu S
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Thu Oct 07 00:00:00 UTC 2021
A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis.
Nature communications
Wang G,Xie L,Li B,Sang W,Yan J,Li J,Tian H,Li W,Zhang Z,Tian Y,Dai Y
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Thu Sep 30 00:00:00 UTC 2021
Oxygen-Enriched Metal-Phenolic X-Ray Nanoprocessor for Cancer Radio-Radiodynamic Therapy in Combination with Checkpoint Blockade Immunotherapy.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Sang W,Xie L,Wang G,Li J,Zhang Z,Li B,Guo S,Deng CX,Dai Y
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Mon Feb 01 00:00:00 UTC 2021
Systemic Delivery of Oncolytic Adenovirus to Tumors Using Tumor-Infiltrating Lymphocytes as Carriers.
Cells
Santos J,Heiniö C,Quixabeira D,Zafar S,Clubb J,Pakola S,Cervera-Carrascon V,Havunen R,Kanerva A,Hemminki A
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Thu Apr 22 00:00:00 UTC 2021
Milk-derived extracellular vesicles alleviate ulcerative colitis by regulating the gut immunity and reshaping the gut microbiota.
Theranostics
Tong L,Hao H,Zhang Z,Lv Y,Liang X,Liu Q,Liu T,Gong P,Zhang L,Cao F,Pastorin G,Lee CN,Chen X,Wang JW,Yi H
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Fri Jan 28 00:00:00 UTC 2022
Inducible T-Cell Costimulator Mediates Lymphocyte/Macrophage Interactions During Liver Repair.
Frontiers in immunology
Ramavath NN,Gadipudi LL,Provera A,Gigliotti LC,Boggio E,Bozzola C,Albano E,Dianzani U,Sutti S
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Mon Feb 14 00:00:00 UTC 2022
Remote Limb Ischemic Postconditioning Protects Against Ischemic Stroke by Promoting Regulatory T Cells Thriving.
Journal of the American Heart Association
Yu HH,Ma XT,Ma X,Chen M,Chu YH,Wu LJ,Wang W,Qin C,Tian DS
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Nov 16 00:00:00 UTC 2021
Sequential Treatment of Bioresponsive Nanoparticles Elicits Antiangiogenesis and Apoptosis and Synergizes with a CD40 Agonist for Antitumor Immunity.
ACS nano
Ling X,Jiang X,Li Y,Han W,Rodriguez M,Xu Z,Lin W
12-0041-82 was used in flow cytometry to sequential delivery of antiangiogenic and chemotherapeutic agents with bioresponsive NPs activates tumor microenvironments and synergizes with CD40 agonist to regress transplanted tumors and inhibit disseminated tumors in a lung cancer mouse model.
Tue Jan 26 00:00:00 UTC 2021
EGCG Inhibits Tumor Growth in Melanoma by Targeting JAK-STAT Signaling and Its Downstream PD-L1/PD-L2-PD1 Axis in Tumors and Enhancing Cytotoxic T-Cell Responses.
Pharmaceuticals (Basel, Switzerland)
Ravindran Menon D,Li Y,Yamauchi T,Osborne DG,Vaddi PK,Wempe MF,Zhai Z,Fujita M
12-0041-82 was used in Flow cytometry/Cell sorting to demonstrate that EGCG enhances anti-tumor immune responses by inhibiting JAK-STAT signaling in melanoma.
Tue Oct 26 00:00:00 UTC 2021
Immune-tolerance to human iPS-derived neural progenitors xenografted into the immature cerebellum is overridden by species-specific differences in differentiation timing.
Scientific reports
Nato G,Corti A,Parmigiani E,Jachetti E,Lecis D,Colombo MP,Delia D,Buffo A,Magrassi L
12-0041-82 was used in Flow Cytometry to monitor xeno-transplanted human neural precursor cells derived from induced pluripotent stem cells into the cerebellum and brainstem of mice and rats during prenatal development or the first postnatal week.
Tue Jan 12 00:00:00 UTC 2021
Placenta-Expanded Stromal Cell Therapy in a Rodent Model of Simulated Weightlessness.
Cells
Rubinstein L,Paul AM,Houseman C,Abegaz M,Tabares Ruiz S,O'Neil N,Kunis G,Ofir R,Cohen J,Ronca AE,Globus RK,Tahimic CGT
12-0041-82 was used in Flow Cytometry to support the therapeutic potential of placenta-derived stromal cells for select physiological deficits during simulated spaceflight.
Mon Apr 19 00:00:00 UTC 2021
Epinephrine Production in Th17 Cells and Experimental Autoimmune Encephalitis.
Frontiers in immunology
Yang P,Tian H,Zou YR,Chambon P,Ichinose H,Honig G,Diamond B,Kim SJ
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Mon Jul 05 00:00:00 UTC 2021
Aging-dependent mitochondrial dysfunction mediated by ceramide signaling inhibits antitumor T cell response.
Cell reports
Vaena S,Chakraborty P,Lee HG,Janneh AH,Kassir MF,Beeson G,Hedley Z,Yalcinkaya A,Sofi MH,Li H,Husby ML,Stahelin RV,Yu XZ,Mehrotra S,Ogretmen B
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Immunocytochemistry
Tue May 04 00:00:00 UTC 2021
Antagonistic Inflammatory Phenotypes Dictate Tumor Fate and Response to Immune Checkpoint Blockade.
Immunity
Bonavita E,Bromley CP,Jonsson G,Pelly VS,Sahoo S,Walwyn-Brown K,Mensurado S,Moeini A,Flanagan E,Bell CR,Chiang SC,Chikkanna-Gowda CP,Rogers N,Silva-Santos B,Jaillon S,Mantovani A,Reis e Sousa C,Guerra N,Davis DM,Zelenay S
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Dec 15 00:00:00 UTC 2020
Splenic Capture and In Vivo Intracellular Biodegradation of Biological-Grade Graphene Oxide Sheets.
ACS nano
Newman L,Jasim DA,Prestat E,Lozano N,de Lazaro I,Nam Y,Assas BM,Pennock J,Haigh SJ,Bussy C,Kostarelos K
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Aug 25 00:00:00 UTC 2020
Splenic Capture and In Vivo Intracellular Biodegradation of Biological-Grade Graphene Oxide Sheets.
ACS nano
Newman L,Jasim DA,Prestat E,Lozano N,de Lazaro I,Nam Y,Assas BM,Pennock J,Haigh SJ,Bussy C,Kostarelos K
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Aug 25 00:00:00 UTC 2020
Deregulated Notch and Wnt signaling activates early-stage myeloid regeneration pathways in leukemia.
The Journal of experimental medicine
Kang YA,Pietras EM,Passegué E
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Mon Mar 02 00:00:00 UTC 2020
Notch dimerization and gene dosage are important for normal heart development, intestinal stem cell maintenance, and splenic marginal zone B-cell homeostasis during mite infestation.
PLoS biology
Kobia FM,Preusse K,Dai Q,Weaver N,Hass MR,Chaturvedi P,Stein SJ,Pear WS,Yuan Z,Kovall RA,Kuang Y,Eafergen N,Sprinzak D,Gebelein B,Brunskill EW,Kopan R
12-0041 was used in Flow cytometry/Cell sorting to highlight the role of the environment in malignancy and colitis and is consistent with Notch-dependent anti-parasite immune responses being compromised in Notch dimer-deficient animals.
Thu Oct 01 00:00:00 UTC 2020
Runx proteins mediate protective immunity against Leishmania donovani infection by promoting CD40 expression on dendritic cells.
PLoS pathogens
Akhtar MN,Mishra M,Yadav V,Yadav M,Gujar R,Lal S,Kumar R,Khatri N,Sen P
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Dec 01 00:00:00 UTC 2020
Free fatty acid receptor 4 (FFA4) activation ameliorates 2,4-dinitrochlorobenzene-induced atopic dermatitis by increasing regulatory T cells in mice.
Acta pharmacologica Sinica
Son SE,Park SJ,Koh JM,Im DS
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Thu Oct 01 00:00:00 UTC 2020
Enhanced alleviation of aGVHD by TGF-β1-modified mesenchymal stem cells in mice through shifting MΦ into M2 phenotype and promoting the differentiation of Treg cells.
Journal of cellular and molecular medicine
Wu R,Liu C,Deng X,Chen L,Hao S,Ma L
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Wed Jan 01 00:00:00 UTC 2020
DEK-targeting aptamer DTA-64 attenuates bronchial EMT-mediated airway remodelling by suppressing TGF-β1/Smad, MAPK and PI3K signalling pathway in asthma.
Journal of cellular and molecular medicine
Song Y,Wang Z,Jiang J,Piao Y,Li L,Xu C,Piao H,Li L,Yan G
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Dec 01 00:00:00 UTC 2020
IL-17A-producing T cells exacerbate fine particulate matter-induced lung inflammation and fibrosis by inhibiting PI3K/Akt/mTOR-mediated autophagy.
Journal of cellular and molecular medicine
Cong LH,Li T,Wang H,Wu YN,Wang SP,Zhao YY,Zhang GQ,Duan J
12-0041 was used in Flow cytometry/Cell sorting to suggest that PM2.5 could inhibit autophagy of bronchial epithelial cells and promote pulmonary inflammation and fibrosis by inducing the secretion of IL-17A in γδT and Th17 cells and regulating the PI3K/Akt/mTOR signalling pathway.
Sat Aug 01 00:00:00 UTC 2020
HDAC Inhibitor, CG-745, Enhances the Anti-Cancer Effect of Anti-PD-1 Immune Checkpoint Inhibitor by Modulation of the Immune Microenvironment.
Journal of Cancer
Kim YD,Park SM,Ha HC,Lee AR,Won H,Cha H,Cho S,Cho JM
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Mon Sep 28 00:00:00 UTC 2020
HDAC Inhibitor, CG-745, Enhances the Anti-Cancer Effect of Anti-PD-1 Immune Checkpoint Inhibitor by Modulation of the Immune Microenvironment.
Journal of Cancer
Kim YD,Park SM,Ha HC,Lee AR,Won H,Cha H,Cho S,Cho JM
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Mon Sep 28 00:00:00 UTC 2020
Effects of combined treatment with PD‑L1 Ig and CD40L mAb on immune tolerance in the CBA/J x DBA/2 mouse model.
Molecular medicine reports
Li G,Yang L,Li D,Zhang J,Du L,Xia L,Liu Y,Hu W
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Wed Apr 01 00:00:00 UTC 2020
FUT1 deficiency elicits immune dysregulation and corneal opacity in steady state and under stress.
Cell death & disease
Kim KW,Ryu JS,Ko JH,Kim JY,Kim HJ,Lee HJ,Oh JH,Chung JH,Oh JY
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Fri Apr 24 00:00:00 UTC 2020
Elevated granulocytic myeloid-derived suppressor cells are closely related with elevation of Th17 cells in mice with experimental asthma.
International journal of biological sciences
Xue F,Yu M,Li L,Zhang W,Ma Y,Dong L,Shan W,Zheng Y,Wang T,Feng D,Lv J,Wang X
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Fri Nov 12 00:00:00 UTC 2021
Comparative Analysis of Age-Related Changes in Lacrimal Glands and Meibomian Glands of a C57BL/6 Male Mouse Model.
International journal of molecular sciences
Yoon CH,Ryu JS,Hwang HS,Kim MK
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Thu Jun 11 00:00:00 UTC 2020
Truncated PPM1D Prevents Apoptosis in the Murine Thymus and Promotes Ionizing Radiation-Induced Lymphoma.
Cells
Martinikova AS,Burocziova M,Stoyanov M,Macurek L
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Thu Sep 10 00:00:00 UTC 2020
Artificial Mini Dendritic Cells Boost T Cell-Based Immunotherapy for Ovarian Cancer.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Cheng S,Xu C,Jin Y,Li Y,Zhong C,Ma J,Yang J,Zhang N,Li Y,Wang C,Yang Z,Wang Y
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Wed Apr 01 00:00:00 UTC 2020
Ovarian granulosa cell tumor characterization identifies FOXL2 as an immunotherapeutic target.
JCI insight
Pierini S,Tanyi JL,Simpkins F,George E,Uribe-Herranz M,Drapkin R,Burger R,Morgan MA,Facciabene A
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Thu Aug 20 00:00:00 UTC 2020
Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models.
Communications biology
Waaler J,Mygland L,Tveita A,Strand MF,Solberg NT,Olsen PA,Aizenshtadt A,Fauskanger M,Lund K,Brinch SA,Lycke M,Dybing E,Nygaard V,Bøe SL,Heintz KM,Hovig E,Hammarström C,Corthay A,Krauss S
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Fri Apr 24 00:00:00 UTC 2020
Immunotherapeutic Blockade of CD47 Inhibitory Signaling Enhances Innate and Adaptive Immune Responses to Viral Infection.
Cell reports
Cham LB,Torrez Dulgeroff LB,Tal MC,Adomati T,Li F,Bhat H,Huang A,Lang PA,Moreno ME,Rivera JM,Galkina SA,Kosikova G,Stoddart CA,McCune JM,Myers LM,Weissman IL,Lang KS,Hasenkrug KJ
12-0041 was used in Flow cytometry/Cell sorting to indicate that CD47 blockade not only enhances the function of innate immune cells but also links to adaptive immune responses through improved APC function.
Tue Apr 14 00:00:00 UTC 2020
The Proteomic Landscape of Resting and Activated CD4+ T Cells Reveal Insights into Cell Differentiation and Function.
International journal of molecular sciences
Subbannayya Y,Haug M,Pinto SM,Mohanty V,Meås HZ,Flo TH,Prasad TSK,Kandasamy RK
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Dec 29 00:00:00 UTC 2020
ICOS agonism by JTX-2011 (vopratelimab) requires initial T cell priming and Fc cross-linking for optimal T cell activation and anti-tumor immunity in preclinical models.
PloS one
Hanson A,Elpek K,Duong E,Shallberg L,Fan M,Johnson C,Wallace M,Mabry GR,Sazinsky S,Pepper L,Shu CJ,Sathyanarayanan S,Zuerndorfer S,Simpson T,Gostissa M,Briskin M,Law D,Michaelson J,Harvey CJ
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Mon Nov 16 00:00:00 UTC 2020
Tregitopes regulate the tolerogenic immune response and decrease the foetal death rate in abortion-prone mouse matings.
Scientific reports
Kedzierska AE,Lorek D,Slawek A,Chelmonska-Soyta A
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Mon Jun 29 00:00:00 UTC 2020
Id1 and Id3 Maintain Steady-State Hematopoiesis by Promoting Sinusoidal Endothelial Cell Survival and Regeneration.
Cell reports
Gadomski S,Singh SK,Singh S,Sarkar T,Klarmann KD,Berenschot M,Seaman S,Jakubison B,Gudmundsson KO,Lockett S,Keller JR
12-0041 was used in Flow cytometry/Cell sorting to investigate the effects of loss of ld genes on adult endothelial cell.
Tue Apr 28 00:00:00 UTC 2020
Bixin Attenuates Experimental Autoimmune Encephalomyelitis by Suppressing TXNIP/NLRP3 Inflammasome Activity and Activating NRF2 Signaling.
Frontiers in immunology
Yu Y,Wu DM,Li J,Deng SH,Liu T,Zhang T,He M,Zhao YY,Xu Y
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Mon Jun 21 00:00:00 UTC 2021
Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation.
Nature
Wilkinson AC,Ishida R,Kikuchi M,Sudo K,Morita M,Crisostomo RV,Yamamoto R,Loh KM,Nakamura Y,Watanabe M,Nakauchi H,Yamazaki S
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Mon Jul 01 00:00:00 UTC 2019
Natural Killer Cells Degenerate Intact Sensory Afferents following Nerve Injury.
Cell
Davies AJ,Kim HW,Gonzalez-Cano R,Choi J,Back SK,Roh SE,Johnson E,Gabriac M,Kim MS,Lee J,Lee JE,Kim YS,Bae YC,Kim SJ,Lee KM,Na HS,Riva P,Latremoliere A,Rinaldi S,Ugolini S,Costigan M,Oh SB
12-0041 was used in Flow cytometry/Cell sorting to suggest the therapeutic potential of modulating NK cell function to resolve painful neuropathy through the clearance of partially damaged nerves.
Thu Feb 07 00:00:00 UTC 2019
Characterization of immune cell subtypes in three commonly used mouse strains reveals gender and strain-specific variations.
Laboratory investigation; a journal of technical methods and pathology
Hensel JA,Khattar V,Ashton R,Ponnazhagan S
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Jan 01 00:00:00 UTC 2019
Bryostatin-1 ameliorated experimental colitis in Il-10-/- Mice by protecting the intestinal barrier and limiting immune dysfunction.
Journal of cellular and molecular medicine
Zuo L,Li J,Ge S,Ge Y,Shen M,Wang Y,Zhou C,Wu R,Hu J
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Thu Aug 01 00:00:00 UTC 2019
Lactobacillus rhamnosus GG attenuates tenofovir disoproxil fumarate-induced bone loss in male mice via gut-microbiota-dependent anti-inflammation.
Therapeutic advances in chronic disease
Liu H,Gu R,Li W,Zhou W,Cong Z,Xue J,Liu Y,Wei Q,Zhou Y
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Sat Apr 09 00:00:00 UTC 2022
Interleukin 10 Gene-Modified Bone Marrow-Derived Dendritic Cells Attenuate Liver Fibrosis in Mice by Inducing Regulatory T Cells and Inhibiting the TGF-β/Smad Signaling Pathway.
Mediators of inflammation
Xu Y,Tang X,Yang M,Zhang S,Li S,Chen Y,Liu M,Guo Y,Lu M
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Jun 11 00:00:00 UTC 2019
PD-1 inhibitors dependent CD8+ T cells inhibit mouse colon cancer cell metastasis.
OncoTargets and therapy
Gao CE,Zhang M,Song Q,Dong J
12-0041-82 was used in Flow Cytometry to investigate the function of PD-1 inhibitor on the metastasisi of mouse colon cancer cells.
Mon Apr 11 00:00:00 UTC 2022
IL-31 plays dual roles in lung inflammation in an OVA-induced murine asthma model.
Biology open
Huang J,Yue H,Jiang T,Gao J,Shi Y,Shi B,Wu X,Gou X
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Jan 15 00:00:00 UTC 2019
Antitumor and immunomodulatory effects of a novel multitarget inhibitor, CS2164, in mouse hepatocellular carcinoma models.
Anti-cancer drugs
Zhou Y,Fu C,Kong Y,Pan D,Wang Y,Huang S,Li Z,Ning Z,Lu X,Shan S,Xin L
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Oct 01 00:00:00 UTC 2019
An attenuated Zika virus NS4B protein mutant is a potent inducer of antiviral immune responses.
NPJ vaccines
Li G,Adam A,Luo H,Shan C,Cao Z,Fontes-Garfias CR,Sarathy VV,Teleki C,Winkelmann ER,Liang Y,Sun J,Bourne N,Barrett ADT,Shi PY,Wang T
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Thu Oct 01 00:00:00 UTC 2020
Next Generation Sequencing for Long Non-coding RNAs Profile for CD4+ T Cells in the Mouse Model of Acute Asthma.
Frontiers in genetics
Wang Z,Ji N,Chen Z,Wu C,Sun Z,Yu W,Hu F,Huang M,Zhang M
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Fri Apr 08 00:00:00 UTC 2022
Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles.
Cell reports
Cianciaruso C,Beltraminelli T,Duval F,Nassiri S,Hamelin R,Mozes A,Gallart-Ayala H,Ceada Torres G,Torchia B,Ries CH,Ivanisevic J,De Palma M
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Jun 04 00:00:00 UTC 2019
Sex Differences in Mouse Popliteal Lymph Nodes.
Scientific reports
Dill-Garlow R,Chen KE,Walker AM
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Wed Jan 30 00:00:00 UTC 2019
ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression.
Nature communications
Cao Y,Trillo-Tinoco J,Sierra RA,Anadon C,Dai W,Mohamed E,Cen L,Costich TL,Magliocco A,Marchion D,Klar R,Michel S,Jaschinski F,Reich RR,Mehrotra S,Cubillos-Ruiz JR,Munn DH,Conejo-Garcia JR,Rodriguez PC
12-0041-82 was used in Flow Cytometry to study the intrinsic mediators that render CD8+T cells dysfunctional in the tumour microenvironment.
Wed Mar 20 00:00:00 UTC 2019
TLR1/2 Specific Small-Molecule Agonist Suppresses Leukemia Cancer Cell Growth by Stimulating Cytotoxic T Lymphocytes.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Cen X,Zhu G,Yang J,Yang J,Guo J,Jin J,Nandakumar KS,Yang W,Yin H,Liu S,Cheng K
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Fri May 17 00:00:00 UTC 2019
Aryl hydrocarbon receptor activation modulates γδ intestinal intraepithelial lymphocytes and protects against ischemia/reperfusion injury in the murine small intestine.
Molecular medicine reports
Zhang Z,Pu A,Yu M,Xiao W,Sun L,Cai Y,Yang H
12-0041-82 was used in Flow cytometry/Cell sorting to suggest that the AhR plays an important role in protecting the small intestine from I/R and increasing the γδIEL population by decreasing apoptosis of γδIELs.
Fri Mar 01 00:00:00 UTC 2019
Tissue-Restricted Adaptive Type 2 Immunity Is Orchestrated by Expression of the Costimulatory Molecule OX40L on Group 2 Innate Lymphoid Cells.
Immunity
Halim TYF,Rana BMJ,Walker JA,Kerscher B,Knolle MD,Jolin HE,Serrao EM,Haim-Vilmovsky L,Teichmann SA,Rodewald HR,Botto M,Vyse TJ,Fallon PG,Li Z,Withers DR,McKenzie ANJ
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Jun 19 00:00:00 UTC 2018
CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response.
Cell metabolism
Chatterjee S,Daenthanasanmak A,Chakraborty P,Wyatt MW,Dhar P,Selvam SP,Fu J,Zhang J,Nguyen H,Kang I,Toth K,Al-Homrani M,Husain M,Beeson G,Ball L,Helke K,Husain S,Garrett-Mayer E,Hardiman G,Mehrotra M,Nishimura MI,Beeson CC,Bupp MG,Wu J,Ogretmen B,Paulos CM,Rathmell J,Yu XZ,Mehrotra S
Tue Jan 09 00:00:00 UTC 2018
Nox2 in regulatory T cells promotes angiotensin II-induced cardiovascular remodeling.
The Journal of clinical investigation
Emmerson A,Trevelin SC,Mongue-Din H,Becker PD,Ortiz C,Smyth LA,Peng Q,Elgueta R,Sawyer G,Ivetic A,Lechler RI,Lombardi G,Shah AM
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Mon Jul 02 00:00:00 UTC 2018
Pre-existing Immunity to Oncolytic Virus Potentiates Its Immunotherapeutic Efficacy.
Molecular therapy : the journal of the American Society of Gene Therapy
Ricca JM,Oseledchyk A,Walther T,Liu C,Mangarin L,Merghoub T,Wolchok JD,Zamarin D
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Wed Apr 04 00:00:00 UTC 2018
Proapoptotic BIM Impacts B Lymphoid Homeostasis by Limiting the Survival of Mature B Cells in a Cell-Autonomous Manner.
Frontiers in immunology
Liu R,King A,Bouillet P,Tarlinton DM,Strasser A,Heierhorst J
12-0041 was used in Flow cytometry/Cell sorting to indicate that BIM regulates B cell homeostasis predominantly by limiting the life span of non-activated mature B cells.
Wed May 01 00:00:00 UTC 2019
MicroRNA-126 deficiency enhanced the activation and function of CD4+ T cells by elevating IRS-1 pathway.
Clinical and experimental immunology
Chu F,Hu Y,Zhou Y,Guo M,Lu J,Zheng W,Xu H,Zhao J,Xu L
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Thu Feb 01 00:00:00 UTC 2018
Impact of hyperglycemia on autoimmune pancreatitis and regulatory T-cells.
World journal of gastroenterology
Müller-Graff FT,Fitzner B,Jaster R,Vollmar B,Zechner D
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Sat Jul 28 00:00:00 UTC 2018
Human Interleukin-32γ Plays a Protective Role in an Experimental Model of Visceral Leishmaniasis in Mice.
Infection and immunity
Gomes RS,Silva MVT,Dos Santos JC,van Linge C,Reis JM,Teixeira MM,Pinto SA,Dorta ML,Bai X,Chan ED,Dinarello CA,Oliveira MAP,Joosten LAB,Ribeiro-Dias F
12-0041 was used in Flow cytometry/Cell sorting to study the role of interleukin-32γ in potentiating the Th1/Th17 immune response during experimental visceral leishmaniasis.
Tue May 01 00:00:00 UTC 2018
Effect of immune tolerance induced by immature dendritic cells and CTLA4-Ig on systemic lupus erythematosus: An in vivo study.
Experimental and therapeutic medicine
Huang C,Zhang L,Ling F,Wen S,Luo Y,Liu H,Liu J,Zheng W,Liang M,Sun J,Lin YK
12-0041-82 was used in Flow Cytometry to suggest that combined treatment with IL-10-DCs and CTLA4-Ig may be a promising novel therapeutic strategy for the treatment of SLE.
Thu Mar 01 00:00:00 UTC 2018
Baicalin Downregulates RLRs Signaling Pathway to Control Influenza A Virus Infection and Improve the Prognosis.
Evidence-based complementary and alternative medicine : eCAM
Pang P,Zheng K,Wu S,Xu H,Deng L,Shi Y,Chen X
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Thu Oct 01 00:00:00 UTC 2020
Sipa1 deficiency unleashes a host-immune mechanism eradicating chronic myelogenous leukemia-initiating cells.
Nature communications
Xu Y,Ikeda S,Sumida K,Yamamoto R,Tanaka H,Minato N
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Fri Mar 02 00:00:00 UTC 2018
Pyruvate dehydrogenase complex stimulation promotes immunometabolic homeostasis and sepsis survival.
JCI insight
McCall CE,Zabalawi M,Liu T,Martin A,Long DL,Buechler NL,Arts RJW,Netea M,Yoza BK,Stacpoole PW,Vachharajani V
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Thu Aug 09 00:00:00 UTC 2018
CD4+ T cells are activated in regional lymph nodes and migrate to skin to initiate lymphedema.
Nature communications
García Nores GD,Ly CL,Cuzzone DA,Kataru RP,Hespe GE,Torrisi JS,Huang JJ,Gardenier JC,Savetsky IL,Nitti MD,Yu JZ,Rehal S,Mehrara BJ
12-0041 was used in Flow cytometry/Cell sorting to demonstrate that blocking T cell release from lymph nodes using a sphingosine-1-phosphate receptor modulator prevents lymphedema.
Thu May 17 00:00:00 UTC 2018
Glutathione de novo synthesis but not recycling process coordinates with glutamine catabolism to control redox homeostasis and directs murine T cell differentiation.
eLife
Lian G,Gnanaprakasam JR,Wang T,Wu R,Chen X,Liu L,Shen Y,Yang M,Yang J,Chen Y,Vasiliou V,Cassel TA,Green DR,Liu Y,Fan TW,Wang R
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Mon Sep 10 00:00:00 UTC 2018
STIM1 and STIM2 Mediate Cancer-Induced Inflammation in T Cell Acute Lymphoblastic Leukemia.
Cell reports
Saint Fleur-Lominy S,Maus M,Vaeth M,Lange I,Zee I,Suh D,Liu C,Wu X,Tikhonova A,Aifantis I,Feske S
12-0041 was used in Flow cytometry/Cell sorting to investigate the role of store-operated Ca2+ entry mediated by ORAI1, and STIM1 and STIM2 in T-cell acute lymphoblastic leukaemia.
Tue Sep 11 00:00:00 UTC 2018
Inflammation caused by peripheral immune cells across into injured mouse blood brain barrier can worsen postoperative cognitive dysfunction induced by isoflurane.
BMC cell biology
Zhu H,Liu W,Fang H
12-0041 was used in Flow cytometry/Cell sorting to study the underlying mechanism by which blood-brain barrier disruption promotes postoperative cognitive dysfunction in the elderly population.
Sat Sep 29 00:00:00 UTC 2018
A cancer vaccine-mediated postoperative immunotherapy for recurrent and metastatic tumors.
Nature communications
Wang T,Wang D,Yu H,Feng B,Zhou F,Zhang H,Zhou L,Jiao S,Li Y
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Wed Apr 18 00:00:00 UTC 2018
Photosensitizer Micelles Together with IDO Inhibitor Enhance Cancer Photothermal Therapy and Immunotherapy.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Peng J,Xiao Y,Li W,Yang Q,Tan L,Jia Y,Qu Y,Qian Z
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue May 01 00:00:00 UTC 2018
Differential cell-intrinsic regulations of germinal center B and T cells by miR-146a and miR-146b.
Nature communications
Cho S,Lee HM,Yu IS,Choi YS,Huang HY,Hashemifar SS,Lin LL,Chen MC,Afanasiev ND,Khan AA,Lin SW,Rudensky AY,Crotty S,Lu LF
12-0041 was used in Immunohistochemistry to reveal differential cell-intrinsic regulations of GC B and Tfh cells by miR-146a and miR-146b.
Mon Jul 16 00:00:00 UTC 2018
A stochastic epigenetic switch controls the dynamics of T-cell lineage commitment.
eLife
Ng KK,Yui MA,Mehta A,Siu S,Irwin B,Pease S,Hirose S,Elowitz MB,Rothenberg EV,Kueh HY
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Nov 20 00:00:00 UTC 2018
Microglia prevent peripheral immune cell invasion and promote an anti-inflammatory environment in the brain of APP-PS1 transgenic mice.
Journal of neuroinflammation
Unger MS,Schernthaner P,Marschallinger J,Mrowetz H,Aigner L
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Fri Sep 21 00:00:00 UTC 2018
The Chaperone UNC93B1 Regulates Toll-like Receptor Stability Independently of Endosomal TLR Transport.
Immunity
Pelka K,Bertheloot D,Reimer E,Phulphagar K,Schmidt SV,Christ A,Stahl R,Watson N,Miyake K,Hacohen N,Haas A,Brinkmann MM,Marshak-Rothstein A,Meissner F,Latz E
12-0041-82 was used in Flow Cytometry to report that UNC93B1 regulates a step upstream of the differential TLR trafficking process.
Tue May 15 00:00:00 UTC 2018
Macrophage Depletion Protects against Cigarette Smoke-Induced Inflammatory Response in the Mouse Colon and Lung.
Frontiers in physiology
Lim D,Kim W,Lee C,Bae H,Kim J
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Wed Sep 30 00:00:00 UTC 2020
Live imaging and tracking of genome regions in CRISPR/dCas9 knock-in mice.
Genome biology
Duan J,Lu G,Hong Y,Hu Q,Mai X,Guo J,Si X,Wang F,Zhang Y
12-0041 was used in Flow cytometry/Cell sorting to generate and characterise a mouse strain with dCas9-EGFP ubiquitously expressed in various tissues.
Thu Nov 08 00:00:00 UTC 2018
Inhibiting Glycogen Synthase Kinase 3 Reverses Obesity-Induced White Adipose Tissue Inflammation by Regulating Apoptosis Inhibitor of Macrophage/CD5L-Mediated Macrophage Migration.
Arteriosclerosis, thrombosis, and vascular biology
Wang L,Wang Y,Zhang C,Li J,Meng Y,Dou M,Noguchi CT,Di L
12-0041-82 was used in Flow cytometry/Cell sorting to examine the potential mechanism by which GSK3 in modulating obesity-induced visceral adipose tissue (VAT) inflammation.
Sat Sep 01 00:00:00 UTC 2018
CD24-p53 axis suppresses diethylnitrosamine-induced hepatocellular carcinogenesis by sustaining intrahepatic macrophages.
Cell discovery
Li D,Hu M,Liu Y,Ye P,Du P,Li CS,Cheng L,Liu P,Jiang J,Su L,Wang S,Zheng P,Liu Y
12-0041-82 was used in Flow cytometry/Cell sorting to show that targeted mutation of Cd24 dramatically increased HCC burden while reducing intrahepatic macrophages and DEN-induced hepatocyte apoptosis.
Thu Oct 01 00:00:00 UTC 2020
Plasmodium co-infection protects against chikungunya virus-induced pathologies.
Nature communications
Teo TH,Lum FM,Ghaffar K,Chan YH,Amrun SN,Tan JJL,Lee CYP,Chua TK,Carissimo G,Lee WWL,Claser C,Rajarethinam R,Rénia L,Ng LFP
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Sep 25 00:00:00 UTC 2018
Apigenin suppresses PD-L1 expression in melanoma and host dendritic cells to elicit synergistic therapeutic effects.
Journal of experimental & clinical cancer research : CR
Xu L,Zhang Y,Tian K,Chen X,Zhang R,Mu X,Wu Y,Wang D,Wang S,Liu F,Wang T,Zhang J,Liu S,Zhang Y,Tu C,Liu H
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Mon Oct 29 00:00:00 UTC 2018
Microbiota Reconstitution Does Not Cause Bone Loss in Germ-Free Mice.
mSphere
Quach D,Collins F,Parameswaran N,McCabe L,Britton RA
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Wed Nov 20 00:00:00 UTC 2019
CD4 T cell autophagy is integral to memory maintenance.
Scientific reports
Murera D,Arbogast F,Arnold J,Bouis D,Muller S,Gros F
12-0041 was used in Flow cytometry/Cell sorting to propose that memory CD4+ T-cells rely on autophagy for their survival to regulate toxicity of mitochondrial activity and lipid overload.
Fri Apr 13 00:00:00 UTC 2018
Transcription factors early growth response gene (Egr) 2 and 3 control inflammatory responses of tolerant T cells.
Immunity, inflammation and disease
Omodho B,Miao T,Symonds ALJ,Singh R,Li S,Wang P
12-0041 was used in Flow cytometry/Cell sorting to show that despite impaired proliferation and IL2 production, tolerant T cells can display inflammatory responses in response to antigen stimulation and this is controlled at least partly by Egr2 and 3.
Fri Jun 01 00:00:00 UTC 2018
Interleukin-33-Activated Islet-Resident Innate Lymphoid Cells Promote Insulin Secretion through Myeloid Cell Retinoic Acid Production.
Immunity
Dalmas E,Lehmann FM,Dror E,Wueest S,Thienel C,Borsigova M,Stawiski M,Traunecker E,Lucchini FC,Dapito DH,Kallert SM,Guigas B,Pattou F,Kerr-Conte J,Maechler P,Girard JP,Konrad D,Wolfrum C,Böni-Schnetzler M,Finke D,Donath MY
12-0041 was used in Flow cytometry/Cell sorting to provide evidence that an immunometabolic crosstalk between islet-derived IL-33, ILC2s, and myeloid cells fosters insulin secretion.
Tue Nov 21 00:00:00 UTC 2017
Store-Operated Ca2+ Entry Controls Clonal Expansion of T Cells through Metabolic Reprogramming.
Immunity
Vaeth M,Maus M,Klein-Hessling S,Freinkman E,Yang J,Eckstein M,Cameron S,Turvey SE,Serfling E,Berberich-Siebelt F,Possemato R,Feske S
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Oct 17 00:00:00 UTC 2017
Eradication of Tumors through Simultaneous Ablation of CD276/B7-H3-Positive Tumor Cells and Tumor Vasculature.
Cancer cell
Seaman S,Zhu Z,Saha S,Zhang XM,Yang MY,Hilton MB,Morris K,Szot C,Morris H,Swing DA,Tessarollo L,Smith SW,Degrado S,Borkin D,Jain N,Scheiermann J,Feng Y,Wang Y,Li J,Welsch D,DeCrescenzo G,Chaudhary A,Zudaire E,Klarmann KD,Keller JR,Dimitrov DS,St Croix B
12-0041 was used in Flow cytometry/Cell sorting to demonstrate that the cell surface protein CD276/B7-H3 is broadly over-expressed by multiple tumour types on both cancer cells and tumour-infiltrating blood vessels, making it a potentially ideal dual-compartment therapeutic target.
Mon Apr 10 00:00:00 UTC 2017
Dectin-2 Deficiency Modulates Th1 Differentiation and Improves Wound Healing After Myocardial Infarction.
Circulation research
Yan X,Zhang H,Fan Q,Hu J,Tao R,Chen Q,Iwakura Y,Shen W,Lu L,Zhang Q,Zhang R
12-0041 was used in Flow cytometry/Cell sorting to determine whether Dectin-2 signalling is involved in the healing process and cardiac remodelling after myocardial infarction and to elucidate the underlying molecular mechanisms.
Fri Mar 31 00:00:00 UTC 2017
A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer.
The Journal of clinical investigation
Berlato C,Khan MN,Schioppa T,Thompson R,Maniati E,Montfort A,Jangani M,Canosa M,Kulbe H,Hagemann UB,Duncan AR,Fletcher L,Wilkinson RW,Powles T,Quezada SA,Balkwill FR
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Wed Mar 01 00:00:00 UTC 2017
Egr2 and 3 control adaptive immune responses by temporally uncoupling expansion from T cell differentiation.
The Journal of experimental medicine
Miao T,Symonds ALJ,Singh R,Symonds JD,Ogbe A,Omodho B,Zhu B,Li S,Wang P
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Mon Jun 05 00:00:00 UTC 2017
Oncolytic Adenovirus and Tumor-Targeting Immune Modulatory Therapy Improve Autologous Cancer Vaccination.
Cancer research
Jiang H,Rivera-Molina Y,Gomez-Manzano C,Clise-Dwyer K,Bover L,Vence LM,Yuan Y,Lang FF,Toniatti C,Hossain MB,Fueyo J
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Sat Jul 15 00:00:00 UTC 2017
Engineered erythrocytes covalently linked to antigenic peptides can protect against autoimmune disease.
Proceedings of the National Academy of Sciences of the United States of America
Pishesha N,Bilate AM,Wibowo MC,Huang NJ,Li Z,Deshycka R,Bousbaine D,Li H,Patterson HC,Dougan SK,Maruyama T,Lodish HF,Ploegh HL
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Mar 21 00:00:00 UTC 2017
Betulin from Hedyotis hedyotidea ameliorates concanavalin A-induced and T cell-mediated autoimmune hepatitis in mice.
Acta pharmacologica Sinica
Zhou YQ,Weng XF,Dou R,Tan XS,Zhang TT,Fang JB,Wu XW
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Wed Feb 01 00:00:00 UTC 2017
Cornea lymphatics drive the CD8+ T-cell response to herpes simplex virus-1.
Immunology and cell biology
Gurung HR,Carr MM,Carr DJ
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Sun Jan 01 00:00:00 UTC 2017
ADAR1 deletion induces NFκB and interferon signaling dependent liver inflammation and fibrosis.
RNA biology
Ben-Shoshan SO,Kagan P,Sultan M,Barabash Z,Dor C,Jacob-Hirsch J,Harmelin A,Pappo O,Marcu-Malina V,Ben-Ari Z,Amariglio N,Rechavi G,Goldstein I,Safran M
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Thu May 04 00:00:00 UTC 2017
Location of tumor affects local and distant immune cell type and number.
Immunity, inflammation and disease
Hensel JA,Khattar V,Ashton R,Lee C,Siegal GP,Ponnazhagan S
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Wed Mar 01 00:00:00 UTC 2017
Human amnion cells reverse acute and chronic pulmonary damage in experimental neonatal lung injury.
Stem cell research & therapy
Zhu D,Tan J,Maleken AS,Muljadi R,Chan ST,Lau SN,Elgass K,Leaw B,Mockler J,Chambers D,Leeman KT,Kim CF,Wallace EM,Lim R
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Fri Nov 10 00:00:00 UTC 2017
The Phytochemical Bergenin Enhances T Helper 1 Responses and Anti-Mycobacterial Immunity by Activating the MAP Kinase Pathway in Macrophages.
Frontiers in cellular and infection microbiology
Dwivedi VP,Bhattacharya D,Yadav V,Singh DK,Kumar S,Singh M,Ojha D,Ranganathan A,Van Kaer L,Chattopadhyay D,Das G
12-0041 was used in Flow cytometry/Cell sorting to study the role of bergenin in the activation of MAP kinase and ERK pathways in macrophages for host protection against TB.
Wed Dec 27 00:00:00 UTC 2017
MicroRNA expression profiles in human CD3+ T cells following stimulation with anti-human CD3 antibodies.
BMC research notes
Sousa IG,do Almo MM,Simi KC,Bezerra MA,Andrade RV,Maranhão AQ,Brigido MM
12-0041 was used in Flow cytometry/Cell sorting to study the immunoregulatory mechanism of anti-CD3 antibodies.
Tue Mar 14 00:00:00 UTC 2017
MSC-derived Extracellular Vesicles Attenuate Immune Responses in Two Autoimmune Murine Models: Type 1 Diabetes and Uveoretinitis.
Stem cell reports
Shigemoto-Kuroda T,Oh JY,Kim DK,Jeong HJ,Park SY,Lee HJ,Park JW,Kim TW,An SY,Prockop DJ,Lee RH
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue May 09 00:00:00 UTC 2017
Traditional Herbal Medicine-Derived Sulforaphene LFS-01 Reverses Colitis in Mice by Selectively Altering the Gut Microbiota and Promoting Intestinal Gamma-Delta T Cells.
Frontiers in pharmacology
Li M,Gao J,Tang Y,Liu M,Wu S,Qu K,Long X,Li H,Liu M,Liu Y,Yuan J,Mao L,Liu Y,Zheng X,Wang E,Wang J,Yang Y
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Wed Sep 30 00:00:00 UTC 2020
Rottlerin as a therapeutic approach in psoriasis: Evidence from in vitro and in vivo studies.
PloS one
Min M,Yan BX,Wang P,Landeck L,Chen JQ,Li W,Cai SQ,Zheng M,Man XY
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Jan 16 00:00:00 UTC 2018
Compensatory upregulation of PD-1, LAG-3, and CTLA-4 limits the efficacy of single-agent checkpoint blockade in metastatic ovarian cancer.
Oncoimmunology
Huang RY,Francois A,McGray AR,Miliotto A,Odunsi K
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Jan 12 00:00:00 UTC 2021
Combined Blockade of T Cell Immunoglobulin and Mucin Domain 3 and Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 Results in Durable Therapeutic Efficacy in Mice with Intracranial Gliomas.
Medical science monitor : international medical journal of experimental and clinical research
Li J,Liu X,Duan Y,Liu Y,Wang H,Lian S,Zhuang G,Fan Y
12-0041 was used in Flow cytometry/Cell sorting to indicate that combined blockade of T cell immunoglobulin and mucin domain 3 and carcinoembryonic antigen-related cell adhesion molecule 1 generates robust therapeutic efficacy in mice with intracranial tumours.
Mon Jul 24 00:00:00 UTC 2017
Irgm1 coordinately regulates autoimmunity and host defense at select mucosal surfaces.
JCI insight
Azzam KM,Madenspacher JH,Cain DW,Lai L,Gowdy KM,Rai P,Janardhan K,Clayton N,Cunningham W,Jensen H,Patel PS,Kearney JF,Taylor GA,Fessler MB
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Thu Aug 17 00:00:00 UTC 2017
Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity.
Nature communications
Zamarin D,Holmgaard RB,Ricca J,Plitt T,Palese P,Sharma P,Merghoub T,Wolchok JD,Allison JP
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Mon Feb 13 00:00:00 UTC 2017
A Multistage Subunit Vaccine Effectively Protects Mice Against Primary Progressive Tuberculosis, Latency and Reactivation.
EBioMedicine
Ma J,Teng X,Wang X,Fan X,Wu Y,Tian M,Zhou Z,Li L
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Aug 01 00:00:00 UTC 2017
Host-Protozoan Interactions Protect from Mucosal Infections through Activation of the Inflammasome.
Cell
Chudnovskiy A,Mortha A,Kana V,Kennard A,Ramirez JD,Rahman A,Remark R,Mogno I,Ng R,Gnjatic S,Amir ED,Solovyov A,Greenbaum B,Clemente J,Faith J,Belkaid Y,Grigg ME,Merad M
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Thu Oct 06 00:00:00 UTC 2016
Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression.
Nature immunology
Gerriets VA,Kishton RJ,Johnson MO,Cohen S,Siska PJ,Nichols AG,Warmoes MO,de Cubas AA,MacIver NJ,Locasale JW,Turka LA,Wells AD,Rathmell JC
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Thu Dec 01 00:00:00 UTC 2016
Lymphatic vessels regulate immune microenvironments in human and murine melanoma.
The Journal of clinical investigation
Lund AW,Wagner M,Fankhauser M,Steinskog ES,Broggi MA,Spranger S,Gajewski TF,Alitalo K,Eikesdal HP,Wiig H,Swartz MA
12-0041 was used in Flow cytometry/Cell sorting to suggest that the establishment of tumour-associated inflammation and immunity critically depends on lymphatic vessel remodelling and drainage.
Thu Sep 01 00:00:00 UTC 2016
An Effective Immuno-PET Imaging Method to Monitor CD8-Dependent Responses to Immunotherapy.
Cancer research
Tavaré R,Escuin-Ordinas H,Mok S,McCracken MN,Zettlitz KA,Salazar FB,Witte ON,Ribas A,Wu AM
12-0041 was used in Flow cytometry/Cell sorting to investigate anti-CD8 immuno-PET as a sensitive tool for tracking systemic and tumour-infiltrating CD8+ T cell expression in tumour immunotherapy models.
Fri Jan 01 00:00:00 UTC 2016
The 4E-BP-eIF4E axis promotes rapamycin-sensitive growth and proliferation in lymphocytes.
Science signaling
So L,Lee J,Palafox M,Mallya S,Woxland CG,Arguello M,Truitt ML,Sonenberg N,Ruggero D,Fruman DA
12-0041 was used in Flow cytometry/Cell sorting to investigate the mechanism by which rapamycin leads to selective immunosupression of lymphocytes, showing that the 4E-BP-efF4E axis promotes growth and proliferation of lymphocytes and is uniquely sensitive to rapamycin in these cells.
Tue May 31 00:00:00 UTC 2016
MicroRNA-7 Deficiency Ameliorates the Pathologies of Acute Lung Injury through Elevating KLF4.
Frontiers in immunology
Zhao J,Chen C,Guo M,Tao Y,Cui P,Zhou Y,Qin N,Zheng J,Zhang J,Xu L
12-0041 was used in Flow cytometry/Cell sorting to study the role of microRNA-7 in acute lung injury, allowing the development of new therapeutic strategies against inflammatory lung disease.
Wed Mar 16 00:00:00 UTC 2022
Distinctive Expression of Bcl-2 Factors in Regulatory T Cells Determines a Pharmacological Target to Induce Immunological Tolerance.
Frontiers in immunology
Gabriel SS,Bon N,Chen J,Wekerle T,Bushell A,Fehr T,Cippà PE
12-0041 was used in Flow cytometry/Cell sorting to show that blocking the intrinsic apoptosis pathway with a Bcl-2/Bcl-xL inhibitor (ABT-737) caused a selective depletion of effector T cells and a relative enrichment of Tregs in vivo.
Mon Mar 14 00:00:00 UTC 2016
Macrophages transfer antigens to dendritic cells by releasing exosomes containing dead-cell-associated antigens partially through a ceramide-dependent pathway to enhance CD4(+) T-cell responses.
Immunology
Xu Y,Liu Y,Yang C,Kang L,Wang M,Hu J,He H,Song W,Tang H
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Sat Oct 01 00:00:00 UTC 2016
p(⁷⁰S⁶K¹) in the TORC1 pathway is essential for the differentiation of Th17 Cells, but not Th1, Th2, or Treg cells in mice.
European journal of immunology
Sasaki CY,Chen G,Munk R,Eitan E,Martindale J,Longo DL,Ghosh P
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Fri Jan 01 00:00:00 UTC 2016
Resident T Cells Are Unable To Control Herpes Simplex Virus-1 Activity in the Brain Ependymal Region during Latency.
Journal of immunology (Baltimore, Md. : 1950)
Menendez CM,Jinkins JK,Carr DJ
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Mon Aug 15 00:00:00 UTC 2016
G-CSF-Induced Suppressor IL-10+ Neutrophils Promote Regulatory T Cells That Inhibit Graft-Versus-Host Disease in a Long-Lasting and Specific Way.
Journal of immunology (Baltimore, Md. : 1950)
Perobelli SM,Mercadante AC,Galvani RG,Gonçalves-Silva T,Alves AP,Pereira-Neves A,Benchimol M,Nóbrega A,Bonomo A
12-0041 was used in Flow cytometry/Cell sorting to study the role of incoming IL-10+ neutrophils from G-CSF-treated donor spleen in inhibiting acute graft-versus-host disease.
Tue Nov 01 00:00:00 UTC 2016
B cells establish, but do not maintain, long-lived murine anti-peanut IgE(a).
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
Moutsoglou DM,Dreskin SC
12-0041 was used in Flow cytometry/Cell sorting to study the role of CD20+ cells in maintaining lifelong anti-peanut IgE levels.
Fri Apr 01 00:00:00 UTC 2016
Rapamycin ameliorates CCl4-induced liver fibrosis in mice through reciprocal regulation of the Th17/Treg cell balance.
Molecular medicine reports
Gu L,Deng WS,Sun XF,Zhou H,Xu Q
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Mon Aug 01 00:00:00 UTC 2016
PRDM14 promotes RAG-dependent Notch1 driver mutations in mouse T-ALL.
Biology open
Carofino BL,Ayanga B,Tracey LJ,Brooke-Bisschop T,Justice MJ
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Sun May 15 00:00:00 UTC 2016
IgE-mediated enhancement of CD4(+) T cell responses requires antigen presentation by CD8α(-) conventional dendritic cells.
Scientific reports
Ding Z,Dahlin JS,Xu H,Heyman B
12-0041 was used in Flow cytometry/Cell sorting to elucidate the dendritic cell population involved in the presentation of IgE-Ag complexes during enhanced specific antibody and CD4+ T cell responses.
Thu Jun 16 00:00:00 UTC 2016
Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration.
Nature communications
Brinkman CC,Iwami D,Hritzo MK,Xiong Y,Ahmad S,Simon T,Hippen KL,Blazar BR,Bromberg JS
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Jun 21 00:00:00 UTC 2016
Murine Splenic Natural Killer Cells Do Not Develop Immunological Memory after Re-Encounter with Mycobacterium bovis BCG.
PloS one
Kawahara M,Hasegawa N,Takaku H
12-0041 was used in Flow cytometry/Cell sorting to examine the manner of activation of, and the acquisition of specific memory by, natural killer cells following Bacillus Calmette-Guérin vaccination.
Sun Jul 31 00:00:00 UTC 2016
Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis.
Nature communications
Ruhland MK,Loza AJ,Capietto AH,Luo X,Knolhoff BL,Flanagan KC,Belt BA,Alspach E,Leahy K,Luo J,Schaffer A,Edwards JR,Longmore G,Faccio R,DeNardo DG,Stewart SA
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Wed Jun 08 00:00:00 UTC 2016
p21Cip1 plays a critical role in the physiological adaptation to fasting through activation of PPARα.
Scientific reports
Lopez-Guadamillas E,Fernandez-Marcos PJ,Pantoja C,Muñoz-Martin M,Martínez D,Gómez-López G,Campos-Olivas R,Valverde AM,Serrano M
12-0041 was used in Flow cytometry/Cell sorting to examine the expression of several tumour suppressors upon fasting in mice.
Mon Oct 10 00:00:00 UTC 2016
Interleukin-10 deficiency impairs regulatory T cell-derived neuropilin-1 functions and promotes Th1 and Th17 immunity.
Scientific reports
Wang S,Gao X,Shen G,Wang W,Li J,Zhao J,Wei YQ,Edwards CK
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Thu Apr 14 00:00:00 UTC 2016
NFATc1 supports imiquimod-induced skin inflammation by suppressing IL-10 synthesis in B cells.
Nature communications
Alrefai H,Muhammad K,Rudolf R,Pham DA,Klein-Hessling S,Patra AK,Avots A,Bukur V,Sahin U,Tenzer S,Goebeler M,Kerstan A,Serfling E
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Wed May 25 00:00:00 UTC 2016
Epigallocatechin-3-gallate (EGCG) inhibits imiquimod-induced psoriasis-like inflammation of BALB/c mice.
BMC complementary and alternative medicine
Zhang S,Liu X,Mei L,Wang H,Fang F
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Wed Aug 31 00:00:00 UTC 2016
Adjuvanted multi-epitope vaccines protect HLA-A*11:01 transgenic mice against Toxoplasma gondii.
JCI insight
El Bissati K,Chentoufi AA,Krishack PA,Zhou Y,Woods S,Dubey JP,Vang L,Lykins J,Broderick KE,Mui E,Suzuki Y,Sa Q,Bi S,Cardona N,Verma SK,Fraczek L,Reardon CA,Sidney J,Alexander J,Sette A,Vedvick T,Fox C,Guderian JA,Reed S,Roberts CW,McLeod R
12-0041 was used in Flow cytometry/Cell sorting to develop multi-epitope DNA or protein vaccines with TLR4 ligand emulsion adjuvant to protect against Toxoplasma gondii.
Thu Sep 22 00:00:00 UTC 2016
Flagellin is a strong vaginal adjuvant of a therapeutic vaccine for genital cancer.
Oncoimmunology
Lee SE,Hong SH,Verma V,Lee YS,Duong TN,Jeong K,Uthaman S,Sung YC,Lee JT,Park IK,Min JJ,Rhee JH
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Mon Feb 01 00:00:00 UTC 2016
A Diet Mimicking Fasting Promotes Regeneration and Reduces Autoimmunity and Multiple Sclerosis Symptoms.
Cell reports
Choi IY,Piccio L,Childress P,Bollman B,Ghosh A,Brandhorst S,Suarez J,Michalsen A,Cross AH,Morgan TE,Wei M,Paul F,Bock M,Longo VD
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Jun 07 00:00:00 UTC 2016
TNF-Mediated Restriction of Arginase 1 Expression in Myeloid Cells Triggers Type 2 NO Synthase Activity at the Site of Infection.
Cell reports
Schleicher U,Paduch K,Debus A,Obermeyer S,König T,Kling JC,Ribechini E,Dudziak D,Mougiakakos D,Murray PJ,Ostuni R,Körner H,Bogdan C
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue May 03 00:00:00 UTC 2016
Immune adjuvant effect of a Toxoplasma gondii profilin-like protein in autologous whole-tumor-cell vaccination in mice.
Oncotarget
Pyo KH,Lee YW,Lim SM,Shin EH
12-0041 was used in Flow cytometry/Cell sorting to explore the potential of TgPLP as an adjuvant in autologous whole-tumour-cell vaccines.
Tue Nov 08 00:00:00 UTC 2016
Diet-dependent, microbiota-independent regulation of IL-10-producing lamina propria macrophages in the small intestine.
Scientific reports
Ochi T,Feng Y,Kitamoto S,Nagao-Kitamoto H,Kuffa P,Atarashi K,Honda K,Teitelbaum DH,Kamada N
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Wed Jun 15 00:00:00 UTC 2016
CEACAM1 regulates TIM-3-mediated tolerance and exhaustion.
Nature
Huang YH,Zhu C,Kondo Y,Anderson AC,Gandhi A,Russell A,Dougan SK,Petersen BS,Melum E,Pertel T,Clayton KL,Raab M,Chen Q,Beauchemin N,Yazaki PJ,Pyzik M,Ostrowski MA,Glickman JN,Rudd CE,Ploegh HL,Franke A,Petsko GA,Kuchroo VK,Blumberg RS
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Thu Jan 15 00:00:00 UTC 2015
Injectable, spontaneously assembling, inorganic scaffolds modulate immune cells in vivo and increase vaccine efficacy.
Nature biotechnology
Kim J,Li WA,Choi Y,Lewin SA,Verbeke CS,Dranoff G,Mooney DJ
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Thu Jan 01 00:00:00 UTC 2015
Phosphatase Wip1 controls antigen-independent B-cell development in a p53-dependent manner.
Blood
Yi W,Hu X,Chen Z,Liu L,Tian Y,Chen H,Cong YS,Yang F,Zhang L,Rudolph KL,Zhang Z,Zhao Y,Ju Z
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Thu Jul 30 00:00:00 UTC 2015
CD93 Marks a Non-Quiescent Human Leukemia Stem Cell Population and Is Required for Development of MLL-Rearranged Acute Myeloid Leukemia.
Cell stem cell
Iwasaki M,Liedtke M,Gentles AJ,Cleary ML
12-0041 was used in Flow cytometry/Cell sorting to study how CD93 expression may indicate leukaemia initiating stem cells that have a MLL gene rearrangement.
Thu Oct 01 00:00:00 UTC 2015
Aging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitors.
The Journal of clinical investigation
Henry CJ,Casás-Selves M,Kim J,Zaberezhnyy V,Aghili L,Daniel AE,Jimenez L,Azam T,McNamee EN,Clambey ET,Klawitter J,Serkova NJ,Tan AC,Dinarello CA,DeGregori J
12-0041 was used in Flow cytometry/Cell sorting to conclude that chronic inflammatory microenvironments in old age lead to reductions in the fitness of B cell progenitor populations.
Tue Dec 01 00:00:00 UTC 2015
IKKβ acts as a tumor suppressor in cancer-associated fibroblasts during intestinal tumorigenesis.
The Journal of experimental medicine
Pallangyo CK,Ziegler PK,Greten FR
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Mon Dec 14 00:00:00 UTC 2015
Adaptive Immune Regulation of Mammary Postnatal Organogenesis.
Developmental cell
Plaks V,Boldajipour B,Linnemann JR,Nguyen NH,Kersten K,Wolf Y,Casbon AJ,Kong N,van den Bijgaart RJ,Sheppard D,Melton AC,Krummel MF,Werb Z
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Mon Sep 14 00:00:00 UTC 2015
Mitochondrial ATP transporter Ant2 depletion impairs erythropoiesis and B lymphopoiesis.
Cell death and differentiation
Cho J,Seo J,Lim CH,Yang L,Shiratsuchi T,Lee MH,Chowdhury RR,Kasahara H,Kim JS,Oh SP,Lee YJ,Terada N
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Sep 01 00:00:00 UTC 2015
Mice lacking Axl and Mer tyrosine kinase receptors are susceptible to experimental autoimmune orchitis induction.
Immunology and cell biology
Li N,Liu Z,Zhang Y,Chen Q,Liu P,Cheng CY,Lee WM,Chen Y,Han D
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Sun Mar 01 00:00:00 UTC 2015
The Ubiquitin-like Modifier FAT10 Is Selectively Expressed in Medullary Thymic Epithelial Cells and Modifies T Cell Selection.
Journal of immunology (Baltimore, Md. : 1950)
Buerger S,Herrmann VL,Mundt S,Trautwein N,Groettrup M,Basler M
12-0041 was used in Flow cytometry/Cell sorting to assess the role of FAT10 in modification of thymic Ag presentation and epitope-dependent elimination of self-reactive T cells.
Sun Nov 01 00:00:00 UTC 2015
B cell Rab7 mediates induction of activation-induced cytidine deaminase expression and class-switching in T-dependent and T-independent antibody responses.
Journal of immunology (Baltimore, Md. : 1950)
Pone EJ,Lam T,Lou Z,Wang R,Chen Y,Liu D,Edinger AL,Xu Z,Casali P
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Wed Apr 01 00:00:00 UTC 2015
MicroRNA-15b/16 Enhances the Induction of Regulatory T Cells by Regulating the Expression of Rictor and mTOR.
Journal of immunology (Baltimore, Md. : 1950)
Singh Y,Garden OA,Lang F,Cobb BS
12-0041 was used in Flow cytometry/Cell sorting to understand miRNA function in Treg development..
Tue Dec 15 00:00:00 UTC 2015
Histone deacetylation of memory T lymphocytes by You-Gui-Wan alleviates allergen-induced eosinophilic airway inflammation in asthma.
Chinese medicine
Zhang HP,Fu JJ,Fan T,Zhang WB,Wang ZL,Wang L,Wang G
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Mon Jun 15 00:00:00 UTC 2015
Programmed cell death receptor ligand 1 modulates the regulatory T cells' capacity to repress shock/sepsis-induced indirect acute lung injury by recruiting phosphatase SRC homology region 2 domain-containing phosphatase 1.
Shock (Augusta, Ga.)
Tang L,Bai J,Chung CS,Lomas-Neira J,Chen Y,Huang X,Ayala A
12-0041 was used in Flow cytometry/Cell sorting to investigate the mechanisms by which the programmed cell death receptor 1 ligand suppresses lung injury.
Thu Jan 01 00:00:00 UTC 2015
Mannan-modified adenovirus targeting TERT and VEGFR-2: A universal tumour vaccine.
Scientific reports
Wang Y,Zhang J,Wu Y,Ding ZY,Luo XM,Liu J,Zhong WN,Deng GH,Xia XY,Deng YT,Wei YQ,Jiang Y
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Thu Jun 18 00:00:00 UTC 2015
Distinct in vitro properties of embryonic and extraembryonic fibroblast-like cells are reflected in their in vivo behavior following grafting in the adult mouse brain.
Cell transplantation
Costa R,Bergwerf I,Santermans E,De Vocht N,Praet J,Daans J,Le Blon D,Hoornaert C,Reekmans K,Hens N,Goossens H,Berneman Z,Parolini O,Alviano F,Ponsaerts P
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Mon Nov 16 00:00:00 UTC 2015
Intranasal Administration of Lentiviral miR-135a Regulates Mast Cell and Allergen-Induced Inflammation by Targeting GATA-3.
PloS one
Deng YQ,Yang YQ,Wang SB,Li F,Liu MZ,Hua QQ,Tao ZZ
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue May 31 00:00:00 UTC 2016
H9N2 influenza whole inactivated virus combined with polyethyleneimine strongly enhances mucosal and systemic immunity after intranasal immunization in mice.
Clinical and vaccine immunology : CVI
Qin T,Yin Y,Huang L,Yu Q,Yang Q
12-0041 was used in Flow cytometry/Cell sorting to investigate the immune activity of polyethyleneimine with H9N2 influenza whole inactivated virus, showing that it enhances mucosal and systemic immunity after intranasal immunization.
Wed Apr 01 00:00:00 UTC 2015
dNP2 is a blood-brain barrier-permeable peptide enabling ctCTLA-4 protein delivery to ameliorate experimental autoimmune encephalomyelitis.
Nature communications
Lim S,Kim WJ,Kim YH,Lee S,Koo JH,Lee JA,Yoon H,Kim DH,Park HJ,Kim HM,Lee HG,Yun Kim J,Lee JU,Hun Shin J,Kyun Kim L,Doh J,Kim H,Lee SK,Bothwell ALM,Suh M,Choi JM
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Sep 15 00:00:00 UTC 2015
Interleukin-25 Mediates Transcriptional Control of PD-L1 via STAT3 in Multipotent Human Mesenchymal Stromal Cells (hMSCs) to Suppress Th17 Responses.
Stem cell reports
Wang WB,Yen ML,Liu KJ,Hsu PJ,Lin MH,Chen PM,Sudhir PR,Chen CH,Chen CH,Sytwu HK,Yen BL
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Sep 08 00:00:00 UTC 2015
HGF Gene Modification in Mesenchymal Stem Cells Reduces Radiation-Induced Intestinal Injury by Modulating Immunity.
PloS one
Wang H,Sun RT,Li Y,Yang YF,Xiao FJ,Zhang YK,Wang SX,Sun HY,Zhang QW,Wu CT,Wang LS
12-0041 was used in Flow cytometry/Cell sorting to evaluate the therapeutic effect of hepatocyte growth factor-gene-modified MSCs on radiation-induced intestinal injury.
Tue Jan 26 00:00:00 UTC 2016
Infection with Salmonella enterica Serovar Typhimurium Leads to Increased Proportions of F4/80+ Red Pulp Macrophages and Decreased Proportions of B and T Lymphocytes in the Spleen.
PloS one
Rosche KL,Aljasham AT,Kipfer JN,Piatkowski BT,Konjufca V
12-0041 was used in Flow cytometry/Cell sorting to investigate the cause of Salmonella-induced splenomegaly, showing that significantly increased proportions of F4/80+ red pulp macrophages likely play a major role.
Thu Apr 21 00:00:00 UTC 2016
Sphingosine-1-phosphate receptor 3 promotes leukocyte rolling by mobilizing endothelial P-selectin.
Nature communications
Nussbaum C,Bannenberg S,Keul P,Gräler MH,Gonçalves-de-Albuquerque CF,Korhonen H,von Wnuck Lipinski K,Heusch G,de Castro Faria Neto HC,Rohwedder I,Göthert JR,Prasad VP,Haufe G,Lange-Sperandio B,Offermanns S,Sperandio M,Levkau B
12-0041 was used in Flow cytometry/Cell sorting to investigate how sphingosine-1-phosphate receptor 3 promotes leukocyte rolling by mobilising endothelial P-selectin.
Thu Apr 02 00:00:00 UTC 2015
Identifying gut microbe-host phenotype relationships using combinatorial communities in gnotobiotic mice.
Science translational medicine
Faith JJ,Ahern PP,Ridaura VK,Cheng J,Gordon JI
12-0041 was used in Flow cytometry/Cell sorting to describe a method in which a clonally arrayed collection of cultured, sequenced bacteria was generated from one of several human fecal microbiota samples found to transmit a particular phenotype to recipient germ-free mice.
Wed Jan 22 00:00:00 UTC 2014
CCDC88B is a novel regulator of maturation and effector functions of T cells during pathological inflammation.
The Journal of experimental medicine
Kennedy JM,Fodil N,Torre S,Bongfen SE,Olivier JF,Leung V,Langlais D,Meunier C,Berghout J,Langat P,Schwartzentruber J,Majewski J,Lathrop M,Vidal SM,Gros P
12-0041 was used in Flow cytometry/Cell sorting to suggest that CCDC88B is the morbid gene underlying the pleiotropic effect of the 11q13 locus on inflammation.
Mon Dec 15 00:00:00 UTC 2014
CCR10 regulates balanced maintenance and function of resident regulatory and effector T cells to promote immune homeostasis in the skin.
The Journal of allergy and clinical immunology
Xia M,Hu S,Fu Y,Jin W,Yi Q,Matsui Y,Yang J,McDowell MA,Sarkar S,Kalia V,Xiong N
12-0041 was used in Flow cytometry/Cell sorting to investigate the functional importance of CCR10/CCL27 in vivo, showing that CCR10 regulates maintenance and function of regulatory and effector T cells to promote immune homeostasis.
Mon Sep 01 00:00:00 UTC 2014
Autophagy regulates the therapeutic potential of mesenchymal stem cells in experimental autoimmune encephalomyelitis.
Autophagy
Dang S,Xu H,Xu C,Cai W,Li Q,Cheng Y,Jin M,Wang RX,Peng Y,Zhang Y,Wu C,He X,Wan B,Zhang Y
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Jul 01 00:00:00 UTC 2014
Experimental cerebral malaria pathogenesis--hemodynamics at the blood brain barrier.
PLoS pathogens
Nacer A,Movila A,Sohet F,Girgis NM,Gundra UM,Loke P,Daneman R,Frevert U
12-0041 was used in Immunofluorescence to show that significantly more CD8(+) T cells, neutrophils, and macrophages are recruited to postcapillary venules during ECM compared to hyperparasitemia.
Mon Dec 01 00:00:00 UTC 2014
Mast cells expedite control of pulmonary murine cytomegalovirus infection by enhancing the recruitment of protective CD8 T cells to the lungs.
PLoS pathogens
Ebert S,Becker M,Lemmermann NA,Büttner JK,Michel A,Taube C,Podlech J,Böhm V,Freitag K,Thomas D,Holtappels R,Reddehase MJ,Stassen M
12-0041 was used in Flow cytometry/Cell sorting to explore the role of mast cells in the recruitment of protective CD8 T cells to the lungs during systemic infection.
Tue Apr 01 00:00:00 UTC 2014
Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection.
PLoS pathogens
Ataide MA,Andrade WA,Zamboni DS,Wang D,Souza Mdo C,Franklin BS,Elian S,Martins FS,Pereira D,Reed G,Fitzgerald KA,Golenbock DT,Gazzinelli RT
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Wed Jan 01 00:00:00 UTC 2014
Cycloamylose-nanogel drug delivery system-mediated intratumor silencing of the vascular endothelial growth factor regulates neovascularization in tumor microenvironment.
Cancer science
Fujii H,Shin-Ya M,Takeda S,Hashimoto Y,Mukai SA,Sawada S,Adachi T,Akiyoshi K,Miki T,Mazda O
12-0041 was used in Flow cytometry/Cell sorting to develop hydrogel polymer nanoparticles as drug delivery systems.
Mon Dec 01 00:00:00 UTC 2014
Active players in resolution of shock/sepsis induced indirect lung injury: immunomodulatory effects of Tregs and PD-1.
Journal of leukocyte biology
Tang L,Bai J,Chung CS,Lomas-Neira J,Chen Y,Huang X,Ayala A
12-0041 was used in Flow cytometry/Cell sorting to explore the ability of Tregs to modify the innate immune response induced by experimental iALI.
Sat Nov 01 00:00:00 UTC 2014
Depletion of myeloid-derived suppressor cells during interleukin-12 immunogene therapy does not confer a survival advantage in experimental malignant glioma.
Cancer gene therapy
Thaci B,Ahmed AU,Ulasov IV,Wainwright DA,Nigam P,Auffinger B,Tobias AL,Han Y,Zhang L,Moon KS,Lesniak MS
12-0041 was used in Flow cytometry/Cell sorting to investigate how MDSC depletion can affect glioma immunotherapy, showing that it does not confer a survival advantage.
Wed Jan 01 00:00:00 UTC 2014
Kinetics of IFN-γ and IL-17 Production by CD4 and CD8 T Cells during Acute Graft-versus-Host Disease.
Immune network
Ju JM,Lee H,Oh K,Lee DS,Choi EY
12-0041 was used in Flow cytometry/Cell sorting to study production of IFN-γ and IL-17 by CD4 and CD8 T cells during graft-versus-host disease progression.
Tue Apr 01 00:00:00 UTC 2014
Innate IL-17A-producing leukocytes promote acute kidney injury via inflammasome and Toll-like receptor activation.
The American journal of pathology
Chan AJ,Alikhan MA,Odobasic D,Gan PY,Khouri MB,Steinmetz OM,Mansell AS,Kitching AR,Holdsworth SR,Summers SA
12-0041 was used in Immunohistochemistry on frozen tissues to investigate the pathogenic role of IL-17A in cisplatin-induced acute kidney injury.
Thu May 01 00:00:00 UTC 2014
Site-specific chemokine expression regulates central nervous system inflammation and determines clinical phenotype in autoimmune encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950)
Stoolman JS,Duncker PC,Huber AK,Segal BM
12-0041 was used in Flow cytometry/Cell sorting to investigate the role of CXCL2 in atypical EAE, showing that site-specific chemokine expression regulates CNS inflammation and determines clinical phenotype.
Tue Jul 15 00:00:00 UTC 2014
IFN-γ-producing and IL-17-producing γδ T cells differentiate at distinct developmental stages in murine fetal thymus.
Journal of immunology (Baltimore, Md. : 1950)
Shibata K,Yamada H,Nakamura M,Hatano S,Katsuragi Y,Kominami R,Yoshikai Y
12-0041 was used in Flow cytometry/Cell sorting to compare the functions of γδ T cells derived from double-negative 2 and double-negative 3 cells in the murine fetal thymus.
Sat Mar 01 00:00:00 UTC 2014
Mouse mast cell protease-6 and MHC are involved in the development of experimental asthma.
Journal of immunology (Baltimore, Md. : 1950)
Cui Y,Dahlin JS,Feinstein R,Bankova LG,Xing W,Shin K,Gurish MF,Hallgren J
12-0041 was used in Flow cytometry/Cell sorting to compare the immune responses of BALB/c mice to mMCP-6(-/-) and mMCP-6(-/-)/H-2bc mice in a mouse model of experimental asthma.
Sat Nov 15 00:00:00 UTC 2014
Regulation of cyp26a1 on Th17 cells in mouse peri-implantation.
Journal of cellular and molecular medicine
Liu HY,Chao H,Liu ZK,Xia HF,Song Z,Yang Y,Peng JP
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Sat Mar 01 00:00:00 UTC 2014
Nizatidine, a small molecular compound, enhances killed H5N1 vaccine cell-mediated responses and protects mice from lethal viral challenge.
Human vaccines & immunotherapeutics
Wang S,Wu B,Xue J,Wang M,Chen R,Wang B
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Mon Jan 05 00:00:00 UTC 2015
γδ T cells recognize the insulin B:9-23 peptide antigen when it is dimerized through thiol oxidation.
Molecular immunology
Aydintug MK,Zhang L,Wang C,Liang D,Wands JM,Michels AW,Hirsch B,Day BJ,Zhang G,Sun D,Eisenbarth GS,O'Brien RL,Born WK
12-0041 was used in Flow cytometry/Cell sorting to determine why γδ T cells require a secondary amino acid recognition site on the insulin peptide, B:9-23.
Fri Aug 01 00:00:00 UTC 2014
High-dose interferon-γ promotes abortion in mice by suppressing Treg and Th17 polarization.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
Liu HY,Liu ZK,Chao H,Li Z,Song Z,Yang Y,Peng JP
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Thu May 01 00:00:00 UTC 2014
Mechanisms of the immunosuppressive effects of mouse adipose tissue-derived mesenchymal stromal cells on mouse alloreactively stimulated spleen cells.
Experimental and therapeutic medicine
Nagaya R,Mizuno-Kamiya M,Takayama E,Kawaki H,Onoe I,Tanabe T,Nagahara K,Kondoh N
12-0041 was used in Flow cytometry/Cell sorting to demonstrate that adipose tissue-derived mesenchymal stromal cells have significant immune modulatory effects on alloreactively stimulated spleen cells.
Wed Jan 01 00:00:00 UTC 2014
Cellular immunotherapy using irradiated lung cancer cell vaccine co-expressing GM-CSF and IL-18 can induce significant antitumor effects.
BMC cancer
Tian H,Shi G,Yang G,Zhang J,Li Y,Du T,Wang J,Xu F,Cheng L,Zhang X,Dai L,Chen X,Zhang S,Yang Y,Yu D,Wei Y,Deng H
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Wed Jan 29 00:00:00 UTC 2014
Reduced immunogenicity of induced pluripotent stem cells derived from Sertoli cells.
PloS one
Wang X,Qin J,Zhao RC,Zenke M
12-0041 was used in Flow cytometry/Cell sorting to compare immunogenicity of fibroblast- and sertoli cell-derived iPS cells, showing that sertoli cell-derived iPS cells have lower immunogenicity.
Tue Nov 17 00:00:00 UTC 2015
Chronic thoracic spinal cord injury impairs CD8+ T-cell function by up-regulating programmed cell death-1 expression.
Journal of neuroinflammation
Zha J,Smith A,Andreansky S,Bracchi-Ricard V,Bethea JR
12-0041 was used in Flow cytometry/Cell sorting to investigate CD8+ T-cell function by up-regulating programmed cell death-1 expression in chronic thoracic spinal cord injury.
Tue Apr 01 00:00:00 UTC 2014
A chitin-like component on sclerotic cells of Fonsecaea pedrosoi inhibits Dectin-1-mediated murine Th17 development by masking β-glucans.
PloS one
Dong B,Li D,Li R,Chen SC,Liu W,Liu W,Chen L,Chen Y,Zhang X,Tong Z,Xia Y,Xia P,Wang Y,Duan Y
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Mon Sep 28 00:00:00 UTC 2015
Autophagy is a critical regulator of memory CD8(+) T cell formation.
eLife
Puleston DJ,Zhang H,Powell TJ,Lipina E,Sims S,Panse I,Watson AS,Cerundolo V,Townsend AR,Klenerman P,Simon AK
12-0041 was used in Flow cytometry/Cell sorting to show that mice lacking the autophagy gene Atg7 in T cells failed to establish CD8(+) T cell memory to influenza and MCMV infection.
Tue Nov 11 00:00:00 UTC 2014
Elongated TCR alpha chain CDR3 favors an altered CD4 cytokine profile.
BMC biology
Reynolds C,Chong D,Raynsford E,Quigley K,Kelly D,Llewellyn-Hughes J,Altmann D,Boyton R
12-0041 was used in Flow cytometry/Cell sorting to study how the conformation of TCR alpha chain CDR3 favours different CD4 cytokine profiles.
Fri May 09 00:00:00 UTC 2014
Simultaneous inhibition of T helper 2 and T regulatory cell differentiation by small molecules enhances Bacillus Calmette-Guerin vaccine efficacy against tuberculosis.
The Journal of biological chemistry
Bhattacharya D,Dwivedi VP,Kumar S,Reddy MC,Van Kaer L,Moodley P,Das G
12-0041 was used in Flow cytometry/Cell sorting to study the inhibition of Th2 cells and Tregs and the subsequent enhancement of the BCG vaccine efficacy.
Fri Nov 28 00:00:00 UTC 2014
ASK1 promotes the contact hypersensitivity response through IL-17 production.
Scientific reports
Mizukami J,Sato T,Camps M,Ji H,Rueckle T,Swinnen D,Tsuboi R,Takeda K,Ichijo H
12-0041 was used in Flow cytometry/Cell sorting to study the role of ASK1 in the contact hypersensitivity response.
Wed Apr 16 00:00:00 UTC 2014
Small molecule-directed immunotherapy against recurrent infection by Mycobacterium tuberculosis.
The Journal of biological chemistry
Bhattacharya D,Dwivedi VP,Maiga M,Maiga M,Van Kaer L,Bishai WR,Das G
12-0041 was used in Flow cytometry/Cell sorting to investigate small molecule-directed immunotherapy against Th2 and regulatory T cell subsets to reduce recurrent Mycobacterium tuberculosis infection and drug resistance.
Fri Jun 06 00:00:00 UTC 2014
LAMTOR2 regulates dendritic cell homeostasis through FLT3-dependent mTOR signalling.
Nature communications
Scheffler JM,Sparber F,Tripp CH,Herrmann C,Humenberger A,Blitz J,Romani N,Stoitzner P,Huber LA
12-0041 was used in Flow cytometry/Cell sorting to define the effects from the conditional ablation of LAMTOR2 for the dendritic cell compartment in mice.
Wed Oct 22 00:00:00 UTC 2014
Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3⁺ regulatory T cells.
Nature immunology
Pierson W,Cauwe B,Policheni A,Schlenner SM,Franckaert D,Berges J,Humblet-Baron S,Schönefeldt S,Herold MJ,Hildeman D,Strasser A,Bouillet P,Lu LF,Matthys P,Freitas AA,Luther RJ,Weaver CT,Dooley J,Gray DH,Liston A
12-0041 was used in Flow cytometry/Cell sorting to study the regulation of the Foxp3+ T cell pool by proliferation and apoptosis, and specifically the role of antiapoptoic Mcl-1 in T cell survival.
Sun Sep 01 00:00:00 UTC 2013
Moderate aerobic exercise alters migration patterns of antigen specific T helper cells within an asthmatic lung.
Brain, behavior, and immunity
Dugger KJ,Chrisman T,Jones B,Chastain P,Watson K,Estell K,Zinn K,Schwiebert L
12-0041 was used in Flow cytometry/Cell sorting to study how aerobic exercise training can reduce antigen specific Th cell migration into asthmatic lungs.
Fri Nov 01 00:00:00 UTC 2013
The thymic medulla is required for Foxp3+ regulatory but not conventional CD4+ thymocyte development.
The Journal of experimental medicine
Cowan JE,Parnell SM,Nakamura K,Caamano JH,Lane PJ,Jenkinson EJ,Jenkinson WE,Anderson G
12-0041 was used in Flow cytometry/Cell sorting to demonstrate a differential requirement for the thymic medulla in relation to CD4 conventional and Foxp3(+) thymocyte lineages.
Mon Apr 08 00:00:00 UTC 2013
Irf8-regulated genomic responses drive pathological inflammation during cerebral malaria.
PLoS pathogens
Berghout J,Langlais D,Radovanovic I,Tam M,MacMicking JD,Stevenson MM,Gros P
12-0041 was used in Flow cytometry/Cell sorting to show that inactivation of Irf8 confers protection against the development of cerebral malaria.
Tue Feb 18 00:00:00 UTC 2014
Therapeutic evaluation of ex vivo-generated versus natural regulatory T-cells in a mouse model of chronic gut inflammation.
Inflammatory bowel diseases
Karlsson F,Martinez NE,Gray L,Zhang S,Tsunoda I,Grisham MB
12-0041 was used in Flow cytometry/Cell sorting to study the effect of ex vivo-generated and isolated Treg cells on a mouse model of chronic colitis, showing that ex-vivo Tregs were more potent at attenuating colitis, likely due to the associated decrease in IL-6 and IL-17A expression in the colon.
Tue Oct 01 00:00:00 UTC 2013
Cbx4 regulates the proliferation of thymic epithelial cells and thymus function.
Development (Cambridge, England)
Liu B,Liu YF,Du YR,Mardaryev AN,Yang W,Chen H,Xu ZM,Xu CQ,Zhang XR,Botchkarev VA,Zhang Y,Xu GL
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Fri Feb 01 00:00:00 UTC 2013
Absence of CXCL10 aggravates herpes stromal keratitis with reduced primary neutrophil influx in mice.
Journal of virology
Shen FH,Wang SW,Yeh TM,Tung YY,Hsu SM,Chen SH
12-0041 was used in Flow cytometry/Cell sorting to investigate the role of the chemokine CXCL10 in the development of herpetic stromal keratitis.
Thu Aug 01 00:00:00 UTC 2013
A mouse model for inducible overexpression of Prdm14 results in rapid-onset and highly penetrant T-cell acute lymphoblastic leukemia (T-ALL).
Disease models & mechanisms
Carofino BL,Ayanga B,Justice MJ
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Fri Nov 01 00:00:00 UTC 2013
A pathogenic role for CD4+ T cells during Chikungunya virus infection in mice.
Journal of immunology (Baltimore, Md. : 1950)
Teo TH,Lum FM,Claser C,Lulla V,Lulla A,Merits A,Rénia L,Ng LF
12-0041 was used in Flow cytometry/Cell sorting to assess the roles of T cells in Chikungunya virus infection using immunodeficient mice.
Tue Jan 01 00:00:00 UTC 2013
n3 PUFAs reduce mouse CD4+ T-cell ex vivo polarization into Th17 cells.
The Journal of nutrition
Monk JM,Hou TY,Turk HF,McMurray DN,Chapkin RS
12-0041 was used in Flow cytometry/Cell sorting to discern the effect of n3 PUFAs on the CD4+ T-cells of mice.
Sun Sep 01 00:00:00 UTC 2013
Interleukin-22 as a molecular adjuvant facilitates IL-17-producing CD8+ T cell responses against a HBV DNA vaccine in mice.
Human vaccines & immunotherapeutics
Wu B,Zou Q,Hu Y,Wang B
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Oct 01 00:00:00 UTC 2013
Ontogeny and localization of the cells produce IL-2 in healthy animals.
Cytokine
Yamamoto M,Seki Y,Iwai K,Ko I,Martin A,Tsuji N,Miyagawa S,Love RB,Iwashima M
12-0041 was used in Flow cytometry/Cell sorting to study how a group of Tr1 cells may have additional roles in immune homeostasis through IL-2 production to aid in the maintenance of other regulatory T cells..
Fri Mar 01 00:00:00 UTC 2013
Enhanced immune response against HIV-1 induced by a heterologous DNA prime-adenovirus boost vaccination using mannosylated polyethyleneimine as DNA vaccine adjuvant.
International journal of nanomedicine
Li M,Jiang Y,Xu C,Zhang Z,Sun X
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Wed Apr 02 00:00:00 UTC 2014
Distinct translational control in CD4+ T cell subsets.
PLoS genetics
Bjur E,Larsson O,Yurchenko E,Zheng L,Gandin V,Topisirovic I,Li S,Wagner CR,Sonenberg N,Piccirillo CA
12-0041 was used in Flow cytometry/Cell sorting to unveil a unique translational signature which imprints subset-specific protein expression in CD4(+) T cell subsets.
Wed May 01 00:00:00 UTC 2013
Nod2 activates NF-kB in CD4+ T cells but its expression is dispensable for T cell-induced colitis.
PloS one
Zanello G,Goethel A,Forster K,Geddes K,Philpott DJ,Croitoru K
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Thu Jul 31 00:00:00 UTC 2014
Resistance to malaria by enhanced phagocytosis of erythrocytes in LMP7-deficient mice.
PloS one
Duan X,Imai T,Chou B,Tu L,Himeno K,Suzue K,Hirai M,Taniguchi T,Okada H,Shimokawa C,Hisaeda H
12-0041 was used in Flow cytometry/Cell sorting to study how RBCs of LMP7-deficient mice were more likely to deform in response to infection with malaria parasites.
Tue Sep 17 00:00:00 UTC 2013
Targeted deletion of FGL2 leads to increased early viral replication and enhanced adaptive immunity in a murine model of acute viral hepatitis caused by LCMV WE.
PloS one
Khattar R,Luft O,Yavorska N,Shalev I,Phillips MJ,Adeyi O,Gao D,Bartczak A,Urbanellis P,Shyu W,Zhang J,Manuel J,Levy GA,Selzner N
12-0041 was used in Flow cytometry/Cell sorting to demonstrate that targeting FGL2 may enhance the efficacy of current anti-viral therapies for hepatotropic viruses.
Thu Jul 24 00:00:00 UTC 2014
The oxidase activity of vascular adhesion protein-1 (VAP-1) is essential for function.
American journal of clinical and experimental immunology
Noonan T,Lukas S,Peet GW,Pelletier J,Panzenbeck M,Hanidu A,Mazurek S,Wasti R,Rybina I,Roma T,Kronkaitis A,Shoultz A,Souza D,Jiang H,Nabozny G,Modis LK
12-0041 was used in Flow cytometry/Cell sorting to assess the relative contribution of the features of vascular adhesion protein-1 to its function.
Thu Jul 25 00:00:00 UTC 2013
The early activation marker CD69 regulates the expression of chemokines and CD4 T cell accumulation in intestine.
PloS one
Radulovic K,Rossini V,Manta C,Holzmann K,Kestler HA,Niess JH
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Thu Jan 23 00:00:00 UTC 2014
Transcription factor RORα is critical for nuocyte development.
Nature immunology
Wong SH,Walker JA,Jolin HE,Drynan LF,Hams E,Camelo A,Barlow JL,Neill DR,Panova V,Koch U,Radtke F,Hardman CS,Hwang YY,Fallon PG,McKenzie AN
12-0041 was used in Flow cytometry/Cell sorting to study how nuocytes arose in the bone marrow and differentiated from common lymphoid progenitors, indicating they are a distinct, previously unknown member of the lymphoid lineage.
Sun Jan 22 00:00:00 UTC 2012
PGD2-CRTH2 pathway promotes tubulointerstitial fibrosis.
Journal of the American Society of Nephrology : JASN
Ito H,Yan X,Nagata N,Aritake K,Katsumata Y,Matsuhashi T,Nakamura M,Hirai H,Urade Y,Asano K,Kubo M,Utsunomiya Y,Hosoya T,Fukuda K,Sano M
12-0041 was used in Flow cytometry/Cell sorting to explore the contribution of L-PGDS to the development of chronic kidney disease.
Thu Nov 01 00:00:00 UTC 2012
Myeloid-specific tristetraprolin deficiency in mice results in extreme lipopolysaccharide sensitivity in an otherwise minimal phenotype.
Journal of immunology (Baltimore, Md. : 1950)
Qiu LQ,Stumpo DJ,Blackshear PJ
12-0041 was used in Flow cytometry/Cell sorting to show that myeloid-specific TTP deficiency does not phenocopy complete TTP deficiency in C57BL/6 mice.
Tue May 15 00:00:00 UTC 2012
In vivo imaging of differences in early donor cell proliferation in graft-versus-host disease hosts with different pre-conditioning doses.
Molecules and cells
Song MG,Kang B,Jeon JY,Chang J,Lee S,Min CK,Youn H,Choi EY
12-0041 was used in Flow cytometry/Cell sorting to explore the effects of preconditioning irradiation doses on donor cell dynamics in allogeneic graft-versus-host disease hosts.
Sun Jan 01 00:00:00 UTC 2012
Genetic control of susceptibility to infection with Plasmodium chabaudi chabaudi AS in inbred mouse strains.
Genes and immunity
Laroque A,Min-Oo G,Tam M,Radovanovic I,Stevenson MM,Gros P
12-0041 was used in Flow cytometry/Cell sorting to identify genetic effects modulating the blood stage replication of the malarial parasite.
Wed Feb 01 00:00:00 UTC 2012
Augmentation of natural cytotoxicity by chronic low-dose ionizing radiation in murine natural killer cells primed by IL-2.
Journal of radiation research
Sonn CH,Choi JR,Kim TJ,Yu YB,Kim K,Shin SC,Park GH,Shirakawa T,Kim HS,Lee KM
12-0041 was used in Magnetic cell separation to demonstrate how exposure to LDR can lead to subtle immune-enhancing effects on NK cells.
Thu Nov 01 00:00:00 UTC 2012
SA-4-1BBL costimulation inhibits conversion of conventional CD4+ T cells into CD4+ FoxP3+ T regulatory cells by production of IFN-γ.
PloS one
Madireddi S,Schabowsky RH,Srivastava AK,Sharma RK,Yolcu ES,Shirwan H
12-0041 was used in Flow cytometry/Cell sorting to investigate whether 4-1BBL can prevent the conversion of effector CD4+ cells into induced T regulatory cells in tumour settings.
Tue Feb 19 00:00:00 UTC 2013
Interleukin-7 influences FOXP3+CD4+ regulatory T cells peripheral homeostasis.
PloS one
Simonetta F,Gestermann N,Martinet KZ,Boniotto M,Tissières P,Seddon B,Bourgeois C
12-0041 was used in Flow cytometry/Cell sorting to elucidate the mechanisms governing Treg cell survival and homeostasis.
Wed Sep 26 00:00:00 UTC 2012
Aryl Hydrocarbon Receptor-Mediated Perturbations in Gene Expression during Early Stages of CD4(+) T-cell Differentiation.
Frontiers in immunology
Rohlman D,Pham D,Yu Z,Steppan LB,Kerkvliet NI
12-0041 was used in Flow cytometry/Cell sorting to characterise the influence of 2,3,7,8-tetrachlorodibenzo-p-dioxin-activated aryl hydrocarbon receptor on gene expression during CD4+ T-cell differentiation.
Thu Aug 23 00:00:00 UTC 2012
Soluble MOG35-55/I-A(b) dimers ameliorate experimental autoimmune encephalomyelitis by reducing encephalitogenic T cells.
PloS one
Gong Y,Wang Z,Liang Z,Duan H,Ouyang L,Yu Q,Xu Z,Shen G,Weng X,Wu X
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Fri Jul 19 00:00:00 UTC 2013
Human papillomavirus immunization is associated with increased expression of different innate immune regulatory receptors.
Clinical and vaccine immunology : CVI
Colmenares V,Noyola DE,Monsiváis-Urenda A,Salgado-Bustamante M,Estrada-Capetillo L,González-Amaro R,Baranda L
12-0041 was used in Flow cytometry/Cell sorting to study how HPV immunisation alters innate immune receptor function as part of its protective effect.
Sun Jul 01 00:00:00 UTC 2012
Deleterious effect of the IL-23/IL-17A axis and γδT cells on left ventricular remodeling after myocardial infarction.
Journal of the American Heart Association
Yan X,Shichita T,Katsumata Y,Matsuhashi T,Ito H,Ito K,Anzai A,Endo J,Tamura Y,Kimura K,Fujita J,Shinmura K,Shen W,Yoshimura A,Fukuda K,Sano M
12-0041 was used in Flow cytometry/Cell sorting to explore potential immune pathways involved in left ventricular remodelling as possible preventative therapeutic options.
Mon Oct 01 00:00:00 UTC 2012
Impact of enzymatic tissue disintegration on the level of surface molecule expression and immune cell function.
European journal of microbiology & immunology
Autengruber A,Gereke M,Hansen G,Hennig C,Bruder D
12-0041 was used in Flow cytometry/Cell sorting to indicate that enzymatic tissue disintegration can have profound effects on the expression of a variety of cell-surface molecules.
Fri Jun 01 00:00:00 UTC 2012
RelA and RelB transcription factors in distinct thymocyte populations control lymphotoxin-dependent interleukin-17 production in γδ T cells.
Immunity
Powolny-Budnicka I,Riemann M,Tänzer S,Schmid RM,Hehlgans T,Weih F
12-0041 was used in Flow cytometry/Cell sorting to investigate the contribution of NF-κB to IL-17 production by T cells, showing that RelA and RelB in distinct thymocyte populations control lymphotoxin-dependent IL-17 production.
Fri Mar 25 00:00:00 UTC 2011
Foxp3⁺ regulatory T cells exert asymmetric control over murine helper responses by inducing Th2 cell apoptosis.
Blood
Tian L,Altin JA,Makaroff LE,Franckaert D,Cook MC,Goodnow CC,Dooley J,Liston A
12-0041 was used in Flow cytometry/Cell sorting to demonstrate that Th2-driven diseases may be more responsive to regulatory T-cell manipulation.
Thu Aug 18 00:00:00 UTC 2011
Effects of Pre-conditioning Dose on the Immune Kinetics and Cytokine Production in the Leukocytes Infiltrating GVHD Tissues after MHC-matched Transplantation.
Immune network
Choi JH,Yoon H,Min CK,Choi EY
12-0041 was used in Flow cytometry/Cell sorting to analyse chimerism formation and immune kinetics of leukocytes during graft-versus-host disease.
Tue Feb 01 00:00:00 UTC 2011
T cell factor 1 regulates thymocyte survival via a RORγt-dependent pathway.
Journal of immunology (Baltimore, Md. : 1950)
Wang R,Xie H,Huang Z,Ma J,Fang X,Ding Y,Sun Z
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Thu Dec 01 00:00:00 UTC 2011
Angiopoietin 2 stimulates TIE2-expressing monocytes to suppress T cell activation and to promote regulatory T cell expansion.
Journal of immunology (Baltimore, Md. : 1950)
Coffelt SB,Chen YY,Muthana M,Welford AF,Tal AO,Scholz A,Plate KH,Reiss Y,Murdoch C,De Palma M,Lewis CE
12-0041 was used in Immunofluorescence to suggest that ANGPT2-stimulated TIE2-expressing monocytes/macrophages represent a novel, potent immunosuppressive force in tumours.
Fri Apr 01 00:00:00 UTC 2011
Angiopoietin 2 stimulates TIE2-expressing monocytes to suppress T cell activation and to promote regulatory T cell expansion.
Journal of immunology (Baltimore, Md. : 1950)
Coffelt SB,Chen YY,Muthana M,Welford AF,Tal AO,Scholz A,Plate KH,Reiss Y,Murdoch C,De Palma M,Lewis CE
12-0041 was used in Immunofluorescence to suggest that ANGPT2-stimulated TIE2-expressing monocytes/macrophages represent a novel, potent immunosuppressive force in tumours.
Fri Apr 01 00:00:00 UTC 2011
IL-23-dependent and -independent enhancement pathways of IL-17A production by lactic acid.
International immunology
Yabu M,Shime H,Hara H,Saito T,Matsumoto M,Seya T,Akazawa T,Inoue N
12-0041 was used in Flow cytometry/Cell sorting to show lactic acid functions as an inflammatory mediator that activates IL-23-dependent and -independent pathways to promote chronic inflammation in tumour microenvironments.
Sat Jan 01 00:00:00 UTC 2011
A single mid-gestation exposure to TCDD yields a postnatal autoimmune signature, differing by sex, in early geriatric C57BL/6 mice.
Toxicology
Mustafa A,Holladay SD,Witonsky S,Sponenberg DP,Karpuzoglu E,Gogal RM
12-0041 was used in Flow cytometry/Cell sorting to investigate the effect of prenatal TCDD on the postnatal autoimmune status of C57BL/6 mice.
Sun Dec 18 00:00:00 UTC 2011
Requirements for prolongation of allograft survival with regulatory T cell infusion in lymphosufficient hosts.
The Journal of surgical research
Brennan TV,Tang Q,Liu FC,Hoang V,Bi M,Bluestone JA,Kang SM
12-0041 was used in Flow cytometry/Cell sorting to evaluate whether Tregs with a defined allospecificity are more effective than polyclonal Tregs at suppressing allograft rejection.
Fri Jul 01 00:00:00 UTC 2011
CD8 T-cell activation in mice injected with a plasmid DNA vaccine encoding AMA-1 of the reemerging Korean Plasmodium vivax.
The Korean journal of parasitology
Kim HJ,Jung BK,Lee JJ,Pyo KH,Kim TY,Choi BI,Kim TW,Hisaeda H,Himeno K,Shin EH,Chai JY
12-0041 was used in Flow cytometry/Cell sorting to study the cellular immunogenicity of a plasmid DNA vaccine - encoding AMA-1 of Plasmodium vivax - to mice.
Tue Mar 01 00:00:00 UTC 2011
IL-1β promotes TGF-β1 and IL-2 dependent Foxp3 expression in regulatory T cells.
PloS one
Ganesh BB,Bhattacharya P,Gopisetty A,Sheng J,Vasu C,Prabhakar BS
12-0041 was used in Flow cytometry/Cell sorting to investigate the differential effects of IL-12 and IL-1β on Foxp3 expression in T cells, showing that IL-1β promotes TGF-β1- and IL-2-dependent Foxp3 expression in Tregs.
Tue Nov 15 00:00:00 UTC 2011
T regulatory cells maintain intestinal homeostasis by suppressing γδ T cells.
Immunity
Park SG,Mathur R,Long M,Hosh N,Hao L,Hayden MS,Ghosh S
12-0041 was used in Flow cytometry/Cell sorting to explore the regulatory processes maintaining a tolerogenic attitude towards enteric commensal bacteria.
Wed Nov 24 00:00:00 UTC 2010
Structure of the AML1-ETO NHR3-PKA(RIIα) complex and its contribution to AML1-ETO activity.
Journal of molecular biology
Corpora T,Roudaia L,Oo ZM,Chen W,Manuylova E,Cai X,Chen MJ,Cierpicki T,Speck NA,Bushweller JH
12-0041 was used in Flow cytometry/Cell sorting to elucidate the structure and function of the AML1-ETO NHR3-PKA(RIIα) complex.
Fri Sep 24 00:00:00 UTC 2010
Potent antitumor effects of combined therapy with a telomerase-specific, replication-competent adenovirus (OBP-301) and IL-2 in a mouse model of renal cell carcinoma.
Cancer gene therapy
Huang P,Kaku H,Chen J,Kashiwakura Y,Saika T,Nasu Y,Urata Y,Fujiwara T,Watanabe M,Kumon H
12-0041 was used in Flow cytometry/Cell sorting to assess the effectiveness of a combined virus-interleukin therapy against carcinoma.
Thu Jul 01 00:00:00 UTC 2010
Stress-induced glucocorticoids at the earliest stages of herpes simplex virus-1 infection suppress subsequent antiviral immunity, implicating impaired dendritic cell function.
Journal of immunology (Baltimore, Md. : 1950)
Elftman MD,Hunzeker JT,Mellinger JC,Bonneau RH,Norbury CC,Truckenmiller ME
12-0041 was used in Flow cytometry/Cell sorting to investigate the specific mechanism for psychological stress-induced suppression of immune responses.
Mon Feb 15 00:00:00 UTC 2010
Critical protective role for MCP-1 in pneumonic Burkholderia mallei infection.
Journal of immunology (Baltimore, Md. : 1950)
Goodyear A,Jones A,Troyer R,Bielefeldt-Ohmann H,Dow S
12-0041 was used in Flow cytometry/Cell sorting to assess the role of MCP-1 in immunity to acute pneumonia caused by gram-negative bacteria.
Mon Feb 01 00:00:00 UTC 2010
Transient role of CD4+CD25+ regulatory T cells in mycobacterial infection in mice.
International immunology
Ozeki Y,Sugawara I,Udagawa T,Aoki T,Osada-Oka M,Tateishi Y,Hisaeda H,Nishiuchi Y,Harada N,Kobayashi K,Matsumoto S
12-0041 was used in Flow cytometry/Cell sorting to investigate the role of CD4(+)CD25(+) Treg cells in mycobacterial infection.
Mon Mar 01 00:00:00 UTC 2010
Interleukin-6 contributes to age-related alteration of cytokine production by macrophages.
Mediators of inflammation
Gomez CR,Karavitis J,Palmer JL,Faunce DE,Ramirez L,Nomellini V,Kovacs EJ
12-0041 was used in Flow cytometry/Cell sorting to demonstrate in vitro that Interleukin-6 regulates age-related defects in splenic macrophages through alteration of proinflammatory cytokines.
Thu Nov 04 00:00:00 UTC 2010
Thymic alterations in GM2 gangliosidoses model mice.
PloS one
Kanzaki S,Yamaguchi A,Yamaguchi K,Kojima Y,Suzuki K,Koumitsu N,Nagashima Y,Nagahama K,Ehara M,Hirayasu Y,Ryo A,Aoki I,Yamanaka S
12-0041 was used in Flow cytometry/Cell sorting to study the Hexb(-/-) mouse model of Sandhoff disease, showing alterations to the thymus, potentially due to FcRγ.
Tue Aug 10 00:00:00 UTC 2010
Lymphotoxin beta receptor signaling promotes tertiary lymphoid organogenesis in the aorta adventitia of aged ApoE-/- mice.
The Journal of experimental medicine
Gräbner R,Lötzer K,Döpping S,Hildner M,Radke D,Beer M,Spanbroek R,Lippert B,Reardon CA,Getz GS,Fu YX,Hehlgans T,Mebius RE,van der Wall M,Kruspe D,Englert C,Lovas A,Hu D,Randolph GJ,Weih F,Habenicht AJ
12-0041 was used in Flow cytometry/Cell sorting to investigate how the LTbetaR pathway has a major role in shaping the immunological characteristics and overall integrity of the arterial wall.
Fri Jan 16 00:00:00 UTC 2009
Gasp, a Grb2-associating protein, is critical for positive selection of thymocytes.
Proceedings of the National Academy of Sciences of the United States of America
Patrick MS,Oda H,Hayakawa K,Sato Y,Eshima K,Kirikae T,Iemura S,Shirai M,Abe T,Natsume T,Sasazuki T,Suzuki H
12-0041 was used in Flow cytometry/Cell sorting to investigate the molecular mechanisms involved in selection of T cells in the thymus.
Tue Sep 22 00:00:00 UTC 2009
Lack of TNFR2 expression by CD4(+) T cells exacerbates experimental colitis.
European journal of immunology
Dayer Schneider J,Seibold I,Saxer-Sekulic N,Paredes BE,Saurer L,Mueller C
12-0041 was used in Flow cytometry/Cell sorting to assess the role of TNF receptor 2 signalling in the CD4(+) T-cell transfer model of colitis.
Wed Jul 01 00:00:00 UTC 2009
Human CD8+CXCR3+ T cells have the same function as murine CD8+CD122+ Treg.
European journal of immunology
Shi Z,Okuno Y,Rifa'i M,Endharti AT,Akane K,Isobe K,Suzuki H
12-0041-82 was used in Flow Cytometry to suggest that human CD8(+)CXCR3(+) T cells are the counterparts of murine CD8(+)CD122(+) Treg.
Sat Aug 01 00:00:00 UTC 2009
Infection with a helminth parasite attenuates autoimmunity through TGF-beta-mediated suppression of Th17 and Th1 responses.
Journal of immunology (Baltimore, Md. : 1950)
Walsh KP,Brady MT,Finlay CM,Boon L,Mills KH
12-0041 was used in Flow cytometry/Cell sorting to provide evidence that parasites can exert bystander immunosuppression of pathogenic T cells that mediate autoimmune diseases.
Sat Aug 01 00:00:00 UTC 2009
c-Myb is required for pro-B cell differentiation.
Journal of immunology (Baltimore, Md. : 1950)
Fahl SP,Crittenden RB,Allman D,Bender TP
12-0041 was used in Flow cytometry/Cell sorting to demonstrate that c-Myb is absolutely required for the survival and differentiation of CD19(+) B-lineage cells.
Sun Nov 01 00:00:00 UTC 2009
The adaptor molecule signaling lymphocytic activation molecule-associated protein (SAP) regulates IFN-gamma and IL-4 production in V alpha 14 transgenic NKT cells via effects on GATA-3 and T-bet expression.
Journal of immunology (Baltimore, Md. : 1950)
Cen O,Ueda A,Guzman L,Jain J,Bassiri H,Nichols KE,Stein PL
12-0041 was used in Flow cytometry/Cell sorting to study the mechanism by which signalling lymphocytic activation molecule-associated protein exerts control over natural killer T cell development and cytokine production.
Sun Feb 01 00:00:00 UTC 2009
Langerin+ CD8alpha+ dendritic cells are critical for cross-priming and IL-12 production in response to systemic antigens.
Journal of immunology (Baltimore, Md. : 1950)
Farrand KJ,Dickgreber N,Stoitzner P,Ronchese F,Petersen TR,Hermans IF
12-0041 was used in Flow cytometry/Cell sorting to investigate the role of langerin(+)CD8alpha(+) dendritic cells in priming T cells, showing that they are critical for cross-priming and IL-12 production in response to systemic antigens.
Tue Dec 15 00:00:00 UTC 2009
Absence of IFN-beta impairs antigen presentation capacity of splenic dendritic cells via down-regulation of heat shock protein 70.
Journal of immunology (Baltimore, Md. : 1950)
Zietara N,Łyszkiewicz M,Gekara N,Puchałka J,Dos Santos VA,Hunt CR,Pandita TK,Lienenklaus S,Weiss S
12-0041 was used in Flow cytometry/Cell sorting to investigate the role of low level production of IFN, showing that its absence impairs antigen presentation capacity of splenic dendritic cells.
Wed Jul 15 00:00:00 UTC 2009
GITR Blockade Facilitates Treg Mediated Allograft Survival.
Transplantation
Sonawane SB,Kim JI,Lee MK,Lee SH,Duff PE,Moore DJ,Lian MM,Deng S,Choi Y,Yeh H,Caton AJ,Markmann JF
12-0041 was used in Flow cytometry/Cell sorting to study how inflammation and other innate immune signals may activate antigen presenting cells to up-regulate GITR.
Fri Nov 27 00:00:00 UTC 2009
Deletion of both the C3a and C5a receptors fails to protect against experimental autoimmune encephalomyelitis.
Neuroscience letters
Ramos TN,Wohler JE,Barnum SR
12-0041 was used in Flow cytometry/Cell sorting to demonstrate the delayed onset of experimental autoimmune encephalomyelitis but no attenuation of disease severity in C3aR/C5aR double knockout mice.
Thu Dec 31 00:00:00 UTC 2009
Induction of antigen-specific immune tolerance by TGF-beta-induced CD4+Foxp3+ regulatory T cells.
International journal of clinical and experimental medicine
Fan H,Wang J,Zhou X,Liu Z,Zheng SG
12-0041 was used in Flow cytometry/Cell sorting to investigate the use of TGF-beta-induced Treg cells to protect MHC-mismatched organ grafts from rejection in a clinical setting.
Tue Aug 25 00:00:00 UTC 2009
MGL2 Dermal dendritic cells are sufficient to initiate contact hypersensitivity in vivo.
PloS one
Kumamoto Y,Denda-Nagai K,Aida S,Higashi N,Irimura T
12-0041 was used in Flow cytometry/Cell sorting to investigate the functional and phenotypic differences between Langerhans and dermal dendritic cells, showing that macrophage galactose-type C-type lectin (MGL) 2 is only expression in dermal dendritic cells, which are sufficient to initiate contact hypersensitivity in vivo.
Thu Aug 06 00:00:00 UTC 2009
Vaccine adjuvants alter TCR-based selection thresholds.
Immunity
Malherbe L,Mark L,Fazilleau N,McHeyzer-Williams LJ,McHeyzer-Williams MG
12-0041 was used in Flow cytometry/Cell sorting to demonstrate the capacity of adjuvants to modify antigen-specific helper T cell clonal composition.
Thu May 01 00:00:00 UTC 2008
Sequential phases in the development of Aire-expressing medullary thymic epithelial cells involve distinct cellular input.
European journal of immunology
White AJ,Withers DR,Parnell SM,Scott HS,Finke D,Lane PJ,Jenkinson EJ,Anderson G
12-0041 was used in Flow cytometry/Cell sorting to analyse the cellular and molecular requirements for the initial appearance of Aire+ medullary thymic epithelial cells in the embryonic thymus, in addition to their persistence in the adult thymus.
Tue Apr 01 00:00:00 UTC 2008
Loss of extracellular superoxide dismutase leads to acute lung damage in the presence of ambient air: a potential mechanism underlying adult respiratory distress syndrome.
The American journal of pathology
Gongora MC,Lob HE,Landmesser U,Guzik TJ,Martin WD,Ozumi K,Wall SM,Wilson DS,Murthy N,Gravanis M,Fukai T,Harrison DG
12-0041 was used in Flow cytometry/Cell sorting to study the role of acute SOD3 reduction in lung injury.
Wed Oct 01 00:00:00 UTC 2008
Pervasive and stochastic changes in the TCR repertoire of regulatory T-cell-deficient mice.
International immunology
Zheng L,Sharma R,Kung JT,Deshmukh US,Jarjour WN,Fu SM,Ju ST
12-0041 was used in Flow cytometry/Cell sorting to compare the T-cell receptor V beta gene family expression profile of normal and Treg-lacking mice.
Tue Apr 01 00:00:00 UTC 2008
Suppression of alkali burn-induced corneal neovascularization by dendritic cell vaccination targeting VEGF receptor 2.
Investigative ophthalmology & visual science
Mochimaru H,Usui T,Yaguchi T,Nagahama Y,Hasegawa G,Usui Y,Shimmura S,Tsubota K,Amano S,Kawakami Y,Ishida S
Thu May 01 00:00:00 UTC 2008
Lymphotoxin a-dependent and -independent signals regulate stromal organizer cell homeostasis during lymph node organogenesis.
Blood
White A,Carragher D,Parnell S,Msaki A,Perkins N,Lane P,Jenkinson E,Anderson G,Caamaño JH
12-0041 was used in Flow cytometry/Cell sorting to further investigate the mechanisms that regulate the development of stromal organiser cells.
Sat Sep 15 00:00:00 UTC 2007
miR-150, a microRNA expressed in mature B and T cells, blocks early B cell development when expressed prematurely.
Proceedings of the National Academy of Sciences of the United States of America
Zhou B,Wang S,Mayr C,Bartel DP,Lodish HF
12-0041 was used in Immunofluorescence to study how miR-150 can down-regulate mRNAs important for B cell function, and how it can block further B cell development when expressed prematurely.
Tue Apr 24 00:00:00 UTC 2007
Myocardial infarct-sparing effect of adenosine A2A receptor activation is due to its action on CD4+ T lymphocytes.
Circulation
Yang Z,Day YJ,Toufektsian MC,Xu Y,Ramos SI,Marshall MA,French BA,Linden J
Tue Nov 07 00:00:00 UTC 2006
In vivo ablation of CD11c-positive dendritic cells increases susceptibility to herpes simplex virus type 1 infection and diminishes NK and T-cell responses.
Journal of virology
Kassim SH,Rajasagi NK,Zhao X,Chervenak R,Jennings SR
12-0041 was used in Flow cytometry/Cell sorting to investigate the role of different dendritic cell subsets in response to herpes simplex virus type 1 infection in mice.
Sat Apr 01 00:00:00 UTC 2006
Essential roles of CD8+CD122+ regulatory T cells in the maintenance of T cell homeostasis.
The Journal of experimental medicine
Rifa'i M,Kawamoto Y,Nakashima I,Suzuki H
12-0041 was used in Flow cytometry/Cell sorting to investigate the effect of transfer of CD8+CD122+ cells into CD122-deficient neonates, showing that CD8+CD122+ regulatory T cells are essential for T cell homeostasis.
Mon Nov 01 00:00:00 UTC 2004
Involvement of p38 mitogen-activated protein kinase in different stages of thymocyte development.
Blood
Hsu SC,Wu CC,Han J,Lai MZ
12-0041 was used in Western Blotting to demonstrate that, in addition to early thymocyte development, p38 is involved in positive selection.
Sat Feb 01 00:00:00 UTC 2003
Runx3 and Runx1 are required for CD8 T cell development during thymopoiesis.
Proceedings of the National Academy of Sciences of the United States of America
Woolf E,Xiao C,Fainaru O,Lotem J,Rosen D,Negreanu V,Bernstein Y,Goldenberg D,Brenner O,Berke G,Levanon D,Groner Y
Published figure using CD4 monoclonal antibody (Product # 12-0041-82) in Flow Cytometry
Tue Jun 24 00:00:00 UTC 2003
Increased p300 expression inhibits glucocorticoid receptor-T-cell receptor antagonism but does not affect thymocyte positive selection.
Molecular and cellular biology
Yu CT,Feng MH,Shih HM,Lai MZ
12-0041 was used in Western Blotting to determine the effects of increased p300 expression on GR-TCR crosstalk between thymocytes.
Mon Jul 01 00:00:00 UTC 2002
Increased p300 expression inhibits glucocorticoid receptor-T-cell receptor antagonism but does not affect thymocyte positive selection.
Molecular and cellular biology
Yu CT,Feng MH,Shih HM,Lai MZ
12-0041 was used in Western Blotting to determine the effects of increased p300 expression on GR-TCR crosstalk between thymocytes.
Mon Jul 01 00:00:00 UTC 2002
Increased p300 expression inhibits glucocorticoid receptor-T-cell receptor antagonism but does not affect thymocyte positive selection.
Molecular and cellular biology
Yu CT,Feng MH,Shih HM,Lai MZ
12-0041 was used in Western Blotting to determine the effects of increased p300 expression on GR-TCR crosstalk between thymocytes.
Mon Jul 01 00:00:00 UTC 2002
