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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫组化（冰冻） (IHC (F)) |
Assay-dependent | - |
流式细胞分析 (Flow) |
1:50-1:100 | 查看2篇已发表文章 2篇已发表文章 |
免疫沉淀 (IP) |
Assay-dependent | - |
| 产品规格 | |
|---|---|
种属反应 |
Mouse |
已发表种属 |
Mouse |
宿主/亚型 |
Rat / IgG1 |
分类 |
Monoclonal |
类型 |
Antibody |
克隆号 |
MWReg30 |
抗原 |
Purified murine platelets |
偶联物 |
Unconjugated
|
形式 |
Liquid |
浓度 |
1 mg/mL |
纯化类型 |
Protein G |
保存液 |
PBS |
内含物 |
0.09% sodium azide |
保存条件 |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2538353 |
For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL.
CD41 (platelet glycoprotein IIb, ITGA2B) is composed of two subunits -120 kDa a, alpha and 23 kDa b, beta- that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. CD41 is also involved in blood coagulation by mediating platelet aggregation. Upon blood vessel damage, CD41 binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during the early stages of hematopoietic differentiation. Diseases associated with CD41 dysfunction include Glansmann Thrombasthenia, and Platelet type-16 bleeding disorder.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: alpha IIb; CD41; form 1; form 2; GP IIb; GPalpha IIb; GPIIb; Integrin alpha-IIb; Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain; platelet glycoprotein IIb of IIb/II Ia complex; Platelet membrane glycoprotein IIb
基因别名: AI172977; alphaIIb; CD41; CD41B; GpIIb; Itga2b
UniProt ID: (Mouse) Q9QUM0
Entrez Gene ID: (Mouse) 16399
分子生物学功能:
integrin
