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Invitrogen

CD41/CD61 Monoclonal Antibody (PAC-1), Alexa Fluor™ 647

查看其他10个CD41/CD61抗体

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说明书
实验方案
问题与答案
技术支持
说明书
实验方案
问题与答案
技术支持

产品信息

MA562319

应用
建议稀释比
已发表文章

免疫细胞化学 (ICC/IF)

Assay-dependent
-

流式细胞分析 (Flow)

4 µL/100 µL whole blood or 10^6 cells
-
产品规格

种属反应

Human

宿主/亚型

Mouse / IgM, kappa

分类

Monoclonal

类型

Antibody

克隆号

PAC-1

抗原

Human platelets.
查看免疫原

偶联物

Alexa Fluor™ 647 Alexa Fluor™ 647 Alexa Fluor™ 647

激发/发射光谱

650/671 nm 查看光谱 spectra

形式

Liquid

浓度

0.1 mg/mL

纯化类型

Size-exclusion chromatography

保存液

TBS, pH 8, with 0.2% BSA

内含物

15mM sodium azide

保存条件

4°C, store in dark, DO NOT FREEZE!

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

CD41 is a transmembrane glycoprotein (integrin family) composed of two chains GPIIb alpha (heavy chain; 120 kDa) and GPIIb beta (light chain; 23 kDa). CD61 non-covalently associates with CD41.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

How to use the Panel Builder

Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.

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引用该产品

生物信息学

蛋白别名: alphaIIb protein; antigen CD61; CD41; CD61; GPalpha IIb; GPIIb; GPIIIa; Integrin alpha-2b; Integrin alpha-IIb; integrin beta 3; Integrin beta-3; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); platelet fibrinogen receptor, alpha subunit; platelet glycoprotein IIb of IIb/IIIa complex; Platelet membrane glycoprotein IIb; Platelet membrane glycoprotein IIIa; platelet-specific antigen BAK; protein phosphatase 1, regulatory subunit 93

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基因别名: BDPLT16; BDPLT2; CD41; CD41B; CD61; GP2B; GP3A; GPIIb; GPIIIa; GT; GTA; HPA3; ITGA2B; ITGAB; ITGB3; PPP1R93

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UniProt ID: (Human) P08514, (Human) P05106

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Entrez Gene ID: (Human) 3674, (Human) 3690

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功能
protein binding identical protein binding metal ion binding extracellular matrix binding fibrinogen binding virus receptor activity fibronectin binding protease binding protein disulfide isomerase activity platelet-derived growth factor receptor binding coreceptor activity fibroblast growth factor binding enzyme binding C-X3-C chemokine binding insulin-like growth factor I binding neuregulin binding vascular endothelial growth factor receptor 2 binding cell adhesion molecule binding integrin
参与通路
platelet degranulation positive regulation of leukocyte migration cell adhesion cell-matrix adhesion integrin-mediated signaling pathway extracellular matrix organization platelet aggregation positive regulation of protein phosphorylation positive regulation of endothelial cell proliferation cell-substrate junction assembly blood coagulation positive regulation of endothelial cell migration negative regulation of macrophage derived foam cell differentiation negative regulation of lipid storage smooth muscle cell migration cell growth cell migration platelet activation positive regulation of vascular endothelial growth factor receptor signaling pathway cell-substrate adhesion activation of protein kinase activity negative regulation of lipid transport heterotypic cell-cell adhesion substrate adhesion-dependent cell spreading tube development apolipoprotein A-I-mediated signaling pathway wound healing regulation of bone resorption negative regulation of low-density lipoprotein particle receptor biosynthetic process viral entry into host cell vascular endothelial growth factor receptor signaling pathway mesodermal cell differentiation positive regulation of peptidyl-tyrosine phosphorylation negative regulation of lipoprotein metabolic process leukocyte migration negative chemotaxis angiogenesis involved in wound healing
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