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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:500-1:5,000 | - |
免疫组化（石蜡） (IHC (P)) |
1:20-1:200 | - |
酶联免疫吸附实验 (ELISA) |
Assay-Dependent | - |
| 产品规格 | |
|---|---|
种属反应 |
Human, Mouse |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Recombinant Human Membrane cofactor protein (164-325AA) |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1.75 mg/mL |
纯化类型 |
Protein G |
保存液 |
PBS, pH 7.4, with 50% glycerol |
内含物 |
0.03% Proclin 300 |
保存条件 |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2812179 |
CD46 (MCP, membrane cofactor protein) is a multifunctional cell surface transmembrane protein that binds and inactivates C3b and C4b complement fragments, regulates T cell-induced inflammatory responses by either inhibiting (CD46-1 isoform) or increasing (CD46-2 isoform) the contact hypersensitivity reaction. CD46 also serves as a receptor for several human pathogens (both bacteria and viruses), and its ligation alteres T lymphocyte polarization toward antigen-presenting cells or target cells, inhibiting lymphocyte function. CD46 is a protector of placental tissue and is also expressed on the inner acrosomal membrane of spermatozoa.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: antigen identified by monoclonal antibody TRA-2-10; CD46; CD46 antigen, complement regulatory protein; CD46 molecule, complement regulatory protein; complement membrane cofactor protein; measles virus receptor; Membrane cofactor protein; membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen); MGC26544; TLX; trophoblast leucocyte common antigen; Trophoblast leukocyte common antigen; trophoblast-lymphocyte cross-reactive antigen
基因别名: AHUS2; CD46; MCP; MIC10; TLX; TRA2.10
UniProt ID: (Human) P15529, (Mouse) O88174
Entrez Gene ID: (Human) 4179, (Mouse) 17221
