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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • CD49e (Integrin alpha 5) Antibodies

          Invitrogen

          CD49e (Integrin alpha 5) Polyclonal Antibody

          View all (24) CD49e (Integrin alpha 5) antibodies
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          Protocols
          Tech Support

          Cite CD49e (Integrin alpha 5) Polyclonal Antibody

          Datasheet
          Protocols
          Tech Support
          • Antibody Testing Data (3)
          CD49e (Integrin alpha 5) Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          CD49e (Integrin alpha 5) Antibody (PA5-96530) in WB

          Western blot analysis of CD49e (Integrin alpha 5) in extracts of various cell lines. Samples were incubated with CD49e (Integrin alpha 5) Polyclonal antibody (Product # PA5-96530) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          Product Details

          PA5-96530

          Applications
          Tested Dilution
          Publications

          免疫印迹 (WB)

          1:500-1:2,000
          -

          免疫组化(石蜡) (IHC (P))

          1:50-1:200
          -

          免疫细胞化学 (ICC/IF)

          1:50-1:200
          -
          产品规格

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          分类

          Polyclonal

          类型

          Antibody

          Immunogen

          Recombinant fusion protein containing a sequence corresponding to amino acids 750-1000 of human ITGA5.
          View immunogen

          Conjugate

          Unconjugated

          形式

          Liquid

          浓度

          0.43 mg/mL

          纯化类型

          Affinity Chromatography

          保存液

          PBS, pH 7.3, with 50% glycerol

          内含物

          0.02% sodium azide

          保存条件

          -20° C, Avoid Freeze/Thaw Cycles

          RRID

          AB_2808332

          Product Specific Information

          Immunogen sequence: TVPHLRDTKK TIQFDFQILS KNLNNSQSDV VSFRLSVEAQ AQVTLNGVSK PEAVLFPVSD WHPRDQPQKE EDLGPAVHHV YELINQGPSS ISQGVLELSC PQALEGQQLL YVTRVTGLNC TTNHPINPKG LELDPEGSLH HQQKREAPSR SSASSGPQIL KCPEAECFRL RCELGPLHQQ ESQSLQLHFR VWAKTFLQRE HQPFSLQCEA VYKALKMPYR ILPRQLPQKE RQVATAVQWT KAEGSYGVPL W; Positive Samples: A-549, NIH/3T3, HT-1080, Rat heart, Mouse heart; Cellular Location: Membrane, Single-pass type I membrane protein

          Target Information

          The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: CD49 antigen-like family member E; CD49e; fibronectin receptor alpha polypeptide; Fibronectin receptor subunit alpha; fibronectin receptor, alpha polypeptide; fibronectin receptor, alpha subunit; integrin alpha 5; integrin alpha 5 (fibronectin receptor alpha); Integrin alpha-5; Integrin alpha-5 heavy chain; Integrin alpha-5 light chain; Integrin alpha-F; integrin, alpha 5 (fibronectin receptor, alpha polypeptide); very late activation protein 5, alpha subunit; VLA-5

          View more View less

          Gene Aliases: CD49e; FNRA; ITGA5; Itga5_retired; VLA-5; VLA5; VLA5A

          View more View less

          UniProt ID: (Human) P08648, (Mouse) P11688

          View more View less

          Entrez Gene ID: (Human) 3678, (Mouse) 16402, (Rat) 315346

          View more View less

          Molecular Function: integrin

          Function(s)
          angiogenesis cell-substrate junction assembly cell adhesion heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules leukocyte cell-cell adhesion integrin-mediated signaling pathway memory positive regulation of cell-substrate adhesion extracellular matrix organization positive regulation of cell migration positive regulation of vascular endothelial growth factor receptor signaling pathway cell-substrate adhesion cell-cell adhesion mediated by integrin heterotypic cell-cell adhesion wound healing, spreading of epidermal cells endodermal cell differentiation viral entry into host cell positive regulation of peptidyl-tyrosine phosphorylation leukocyte migration positive regulation of sprouting angiogenesis negative regulation of anoikis
          Process(es)
          virus receptor activity epidermal growth factor receptor binding platelet-derived growth factor receptor binding integrin binding protein binding vascular endothelial growth factor receptor 2 binding metal ion binding cell adhesion molecule binding receptor activity
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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