Proteintech

CD6 Polyclonal Antibody

Name: CD6 Polyclonal Antibody
Brand: Proteintech
SKU: 31998-1-AP

查看其他44个CD6抗体

说明书

证书

实验方案

问题与答案

技术支持

说明书

证书

实验方案

问题与答案

技术支持

说明书

证书

实验方案

问题与答案

技术支持

抗体检测数据 (1)

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CD6 Antibody (31998-1-AP) in WB

Various lysates were subjected to SDS PAGE followed by western blot with 32022-1-AP (NAXE antibody) at dilution of 1:10,000 incubated at room temperature for 1.5 hours.

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Immunogen image

Immunogen Image CD6 Polyclonal Antibody

产品信息

31998-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

酶联免疫吸附实验 (ELISA)

Assay-dependent

产品规格

种属反应

Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

CD6 fusion protein Eg1401

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

450 µg/mL

纯化类型

Affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice

产品详细信息

Sequence of this protein is as follows: GLPSPAPSGQ HKNGTIPNMT LDLEERLGIR LVNGSSRCSG SVKVLLESWE PVCAAHWNRA ATEAVCKALN CGDSGKVTYL MPPTSELPPG ATSGNTSSAG NTTWARAPTE RCRGANWQFC KVQDQECSSD RRLVWVTCAE NQAVRLVDGS SRCAGRVEML EHGEWGTVCD DTWDLQDAHV VCKQLKCGWA VKALAGLHFT PGQGPIHRDQ VNCSGTEAYL WDCPGRPGDQ YCGHKEDAGV VCSEHQSWRL TGGIDSCEGQ VEVYFRGVWS TVCDSEWYPS EAKVLCRSLG CGSAVARPRG LPHSLDGRMY YSCKGQEPAL STCSWRFNNS NLCSQSRAAR VVCSGSQRHL NLSTSEVPSR VPVTIESSVP VSVKDKDSQG

靶标信息

CD6, also known as T12, is a member of the scavenger receptor superfamily found on T and B cell subsets, thymocytes, and acute lymphocytic leukemia cells (ALL). CD6 interacts with its ligand CD166/ALCAM (activated leukocyte cell adhesion molecule) and serves as a coreceptor for T cell activation and stabilizer of the immunological synapse. CD6-ALCAM mediated cell adhesion is also important for T cell proliferation. CD6 may exert some its functions via association with CD5, probably by fine-tuning CD5 signaling. Ligation of CD6 has antiapoptotic role in chronic lymphocytic leukemia B cells.

仅用于科研。不用于诊断过程。未经明确授权不得转售。