Invitrogen

CD62L Monoclonal Antibody (Dreg-56), PE

产品信息

MHCD62L04

应用

建议稀释比

已发表文章

流式细胞分析 (Flow)

Assay-Dependent

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产品规格

种属反应

Human

已发表种属

Human

宿主/亚型

Mouse / IgG1, kappa

分类

Monoclonal

类型

Antibody

克隆号

Dreg-56

抗原

Human CD62L

偶联物

激发/发射光谱

565/576 nm 查看光谱

形式

Liquid

纯化类型

purified

保存液

PBS with sucrose, 4mg/mL BSA

内含物

0.1% sodium azide

保存条件

4° C, store in dark

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_10372946

产品详细信息

R-phycoerythrin (PE) is a stable and highly soluble phycobiliprotein which provides maximal absorbance and fluorescence without susceptibility to internal or external fluorescence quenching, thus providing an exceptional quantum yields and molar extinction coefficients.

靶标信息

The human CD62L is a 74-95 kDa glycoprotein member of the selectin family of adhesion receptors. L-Selectin is comprised of an aminoterminal C-type lectin binding domain, an epidermal growth factor-like domain, two short consensus repeat (SCR) sequences homologous to those found in complement binding proteins, a short spacer region, a transmembrane region and a short cytoplasmic region. Human CD62L (L-Selectin) is constitutively expressed on all classes of leukocytes including lymphocytes (except a substantial population of memory T cells), monocytes and polymorphonuclear cells.

Analyte Specific Reagent

How to use the Panel Builder

Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.

Product References

The CREB coactivator CRTC2 controls hepatic lipid metabolism by regulating SREBP1.

Nature

Han J,Li E,Chen L,Zhang Y,Wei F,Liu J,Deng H,Wang Y

MHCD62L04 was used in flow cytometry to study the role of CREB coactivator CRTC2 in hepatic lipid metabolism.

Thu Aug 13 00:00:00 EDT 2015

A single dose of inactivated hepatitis A vaccine promotes HAV-specific memory cellular response similar to that induced by a natural infection.

Vaccine

Melgaço JG,Morgado LN,Santiago MA,Oliveira JM,Lewis-Ximenez LL,Hasselmann B,Cruz OG,Pinto MA,Vitral CL

MHCD62L04 was used in flow cytometry to evaluate the immune efficacy of a single-dose inactivated hepatitis A vaccination.

Fri Jul 31 00:00:00 EDT 2015

Differential expression of human granzymes A, B, and K in natural killer cells and during CD8+ T cell differentiation in peripheral blood.

European journal of immunology

Bratke K,Kuepper M,Bade B,Virchow JC,Luttmann W

MHCD62L04 was used in Flow Cytometry to study the expression pattern of human granzymes A, B and K.

Thu Sep 01 00:00:00 EDT 2005

生物信息学

蛋白别名: CD62 antigen-like family member L; CD62L; gp90-MEL; hLHRc; L-selectin; LAM-1; LECAM1; Leu-8; Leukocyte adhesion molecule 1; Leukocyte surface antigen Leu-8; Leukocyte-endothelial cell adhesion molecule 1; Lymph node homing receptor; lymphocyte adhesion molecule 1; pln homing receptor; TQ1

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基因别名: CD62L; LAM1; LECAM1; LEU8; LNHR; LSEL; LYAM1; PLNHR; SELL; TQ1

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UniProt ID: (Human) P14151

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Entrez Gene ID: (Human) 6402

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功能

protease binding protein binding heparin binding carbohydrate binding glycosphingolipid binding cell adhesion molecule binding

参与通路

cell adhesion response to ATP regulation of immune response leukocyte migration