Invitrogen

CD68 Monoclonal Antibody (ED1), PE

产品信息

MA5-16653

应用	建议稀释比	已发表文章
流式细胞分析 (Flow)	Neat-1:10	-

产品规格
种属反应	Bovine, Rat
宿主/亚型	Mouse / IgG1
分类	Monoclonal
类型	Antibody
克隆号	ED1
抗原	Rat spleen cells
偶联物	PE FITC Unconjugated
激发/发射光谱	查看光谱
形式	Lyophilized
浓度	Conc. Not Determined
纯化类型	Protein A
保存液	PBS with 1% BSA
内含物	0.09% sodium azide
保存条件	4° C, store in dark, DO NOT FREEZE!
RRID	AB_2538147

产品详细信息

Membrane permeabilization is required for flow cytometry applications. For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL.

Reconstitute with 1 mL of distilled water. After reconstitution, store product undiluted at 4°C in the dark.

Mouse anti rat CD68, clone ED1 recognizes the rat ED1 antigen, a heavily glycosylated protein of approximately 90 -110 KDa, also known as rat CD68 (Dijkstra et al. 1985).

靶标信息

CD68 (Macrosialin) is a 110 kDa integral membrane glycoprotein predominantly expressed on the intracellular lysomsomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes. Also, CD68 could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several Acute Myeloid Leukemia studies.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Flow Cytometry

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