IL-21 and IFNα therapy rescues terminally differentiated NK cells and limits SIV reservoir in ART-treated macaques.
Harper J,Huot N,Micci L,Tharp G,King C,Rascle P,Shenvi N,Wang H,Galardi C,Upadhyay AA,Villinger F,Lifson J,Silvestri G,Easley K,Jacquelin B,Bosinger S,Müller-Trutwin M,Paiardini M
Q10059 was used in Flow cytometry/Cell sorting to generate terminally differentiated blood natural killer cells (NKG2a/clowCD16+) with potent human leukocyte antigen-E-restricted activity in response to SIV envelope peptides.
Mon May 17 00:00:00 EDT 2021
A20 upregulation during treated HIV disease is associated with intestinal epithelial cell recovery and function.
Chitre AS,Kattah MG,Rosli YY,Pao M,Deswal M,Deeks SG,Hunt PW,Abdel-Mohsen M,Montaner LJ,Kim CC,Ma A,Somsouk M,McCune JM
Q10059 was used in Flow cytometry/Cell sorting to show that variation in A20 expression during the course of HIV infection could underlie both the development of epithelial dysfunction before the initiation of ART and the recovery of intestinal epithelial integrity thereafter.
Thu Mar 01 00:00:00 EST 2018
Effect of Antiretroviral Therapy on the Memory and Activation Profiles of B Cells in HIV-Infected African Women.
Journal of immunology (Baltimore, Md. : 1950)
Tanko RF,Soares AP,Müller TL,Garrett NJ,Samsunder N,Abdool Karim Q,Abdool Karim SS,Riou C,Burgers WA
Q10059 was used in Flow cytometry/Cell sorting to study the effect of antiretroviral therapy on B cells in HIV infection.
Wed Feb 01 00:00:00 EST 2017
Selective reduction of IFN-γ single positive mycobacteria-specific CD4+ T cells in HIV-1 infected individuals with latent tuberculosis infection.
Tuberculosis (Edinburgh, Scotland)
Riou C,Bunjun R,Müller TL,Kiravu A,Ginbot Z,Oni T,Goliath R,Wilkinson RJ,Burgers WA
Q10059 was used in flow cytometry to explore how HIV-1 alters immunity during latent tuberculosis
Thu Dec 01 00:00:00 EST 2016
Loss of Function of Intestinal IL-17 and IL-22 Producing Cells Contributes to Inflammation and Viral Persistence in SIV-Infected Rhesus Macaques.
Ryan ES,Micci L,Fromentin R,Paganini S,McGary CS,Easley K,Chomont N,Paiardini M
Q10059 was used in Flow cytometry/Cell sorting to show that intestinal IL-17 producing cell function is severely impaired by SIV infection and is not fully normalized despite effective ART.
Mon Feb 01 00:00:00 EST 2016
Differential Impact of In Vivo CD8+ T Lymphocyte Depletion in Controller versus Progressor Simian Immunodeficiency Virus-Infected Macaques.
Journal of virology
Chowdhury A,Hayes TL,Bosinger SE,Lawson BO,Vanderford T,Schmitz JE,Paiardini M,Betts M,Chahroudi A,Estes JD,Silvestri G
Q10059 was used in flow cytometry to elucidate how CD8 positive T cells suppress virus replication during simian immunodeficiency virus infection.
Tue Sep 01 00:00:00 EDT 2015
Quantification of Th1 and Th17 Cells with Intracellular Staining Following PMA/Ionomycin Stimulation.
Current protocols in cytometry
Karlsson F,Hassan-Zahraee M
Q10059 was used in flow cytometry to discuss methods to measure cytokine production by Th1 and Th17 cells
Mon Jan 05 00:00:00 EST 2015
Cytokine diversity in the Th1-dominated human anti-influenza response caused by variable cytokine expression by Th1 cells, and a minor population of uncommitted IL-2+IFNγ- Thpp cells.
Deng N,Weaver JM,Mosmann TR
Q10059 was used in flow cytometry to investigate the anti-influenza responses of T cell subsets
Thu Dec 18 00:00:00 EST 2014
Transcriptional regulation of Munc13-4 expression in cytotoxic lymphocytes is disrupted by an intronic mutation associated with a primary immunodeficiency.
The Journal of experimental medicine
Cichocki F,Schlums H,Li H,Stache V,Holmes T,Lenvik TR,Chiang SC,Miller JS,Meeths M,Anderson SK,Bryceson YT
Q10059 was used in flow cytometry to find Munc13-4 is highly expressed in differentiated human natural killer cells and effector CD8(+) T lymphocytes
Mon Jun 02 00:00:00 EDT 2014
Increased stability and limited proliferation of CD4+ central memory T cells differentiate nonprogressive simian immunodeficiency virus (SIV) infection of sooty mangabeys from progressive SIV infection of rhesus macaques.
Journal of virology
McGary CS,Cervasi B,Chahroudi A,Micci L,Taaffe J,Meeker T,Silvestri G,Davenport MP,Paiardini M
Q10059 was used in Flow cytometry/Cell sorting to provide new insights into the importance of long-term maintenance of CD4(+) TCM homeostasis during HIV/SIV infection.
Tue Apr 01 00:00:00 EDT 2014
CD3ζ-based chimeric antigen receptors mediate T cell activation via cis- and trans-signalling mechanisms: implications for optimization of receptor structure for adoptive cell therapy.
Clinical and experimental immunology
Bridgeman JS,Ladell K,Sheard VE,Miners K,Hawkins RE,Price DA,Gilham DE
Q10059 was used in flow cytometry to elucidate chimeric antigen receptor-mediated T cell activation
Sat Feb 01 00:00:00 EST 2014
Immunological and virological analyses of rhesus macaques immunized with chimpanzee adenoviruses expressing the simian immunodeficiency virus Gag/Tat fusion protein and challenged intrarectally with repeated low doses of SIVmac.
Journal of virology
Cervasi B,Carnathan DG,Sheehan KM,Micci L,Paiardini M,Kurupati R,Tuyishime S,Zhou XY,Else JG,Ratcliffe SJ,Ertl HC,Silvestri G
Q10059 was used in flow cytometry to infect chimpanzee adenovirus-immunized rhesus macaques with simian immunodeficiency virus
Sun Sep 01 00:00:00 EDT 2013
Ki-67 expression reveals strong, transient influenza specific CD4 T cell responses after adult vaccination.
Li X,Miao H,Henn A,Topham DJ,Wu H,Zand MS,Mosmann TR
Q10059 was used in flow cytometry to study influenza-specific CD4 T cells respond to vaccination using Ki67 as a marker.
Fri Jun 29 00:00:00 EDT 2012
CD8+ T cell immunity to 2009 pandemic and seasonal H1N1 influenza viruses.
Scheible K,Zhang G,Baer J,Azadniv M,Lambert K,Pryhuber G,Treanor JJ,Topham DJ
Q10059 was used in flow cytometry to examine human cross-reactive T cells against a pandemic virus.
Thu Mar 03 00:00:00 EST 2011
Techniques to improve the direct ex vivo detection of low frequency antigen-specific CD8+ T cells with peptide-major histocompatibility complex class I tetramers.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Chattopadhyay PK,Melenhorst JJ,Ladell K,Gostick E,Scheinberg P,Barrett AJ,Wooldridge L,Roederer M,Sewell AK,Price DA
Q10059 was used in flow cytometry to study low frequency antigen-specific CD8+ T cells with peptide-major histocompatibility complex class 1 tetramers and techniques to improve the direct ex vivo detection
Sat Nov 01 00:00:00 EDT 2008