Invitrogen

CD82 Polyclonal Antibody

高级验证

This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.

查看其他19个CD82抗体

说明书

实验方案

技术支持

说明书

实验方案

技术支持

Product Image Gallery

CD82 Antibody in Immunohistochemistry (IHC) — Immunohistochemical analysis of CD82 in human skin and skeletal muscle tissues using a CD82 polyclonal antibody (Product # PA5-83042). Corresponding RNA-seq data are presented for the same tissues.

CD82 Antibody in Western Blot (WB) — Western blot analysis of CD82 by a CD82 polyclonal antibody (Product # PA5-83042). Analysis in control (vector only transfected HEK293T lysate) and CD82 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY400808).

CD82 Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of CD82 demonstrates antibody specificity. Immunohistochemical analysis of CD82 using anti-CD82 Polyclonal Antibody (Product #PA5-83042), shows significant staining of CD82 in skin and shows minimal or weak staining in skeletal muscle tissues. The relative expression levels of CD82 within each tissue is shown using RNA-Seq.

产品信息

PA5-83042

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.04-0.4 µg/mL

免疫组化（石蜡） (IHC (P))

1:200-1:500

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human CD82

查看免疫原

偶联物

Unconjugated

形式

Liquid

浓度

0.1 mg/mL

纯化类型

Anitgen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

RRID

AB_2790198

产品详细信息

Immunogen sequence: NMGKLKQEMG GIVTELIRDY NSSREDSLQD AWDYVQAQVK CCGWVSFYNW TDNAELMNRP EVTYPCSCEV KGEEDNSLSV RKGFCEAPGN RTQSGNHPED WPVYQEGC

靶标信息

This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: C33 antigen; CD82; CD82 antigen; IA4; Inducible membrane protein R2; kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4)); Metastasis suppressor Kangai-1; Suppressor of tumorigenicity 6 protein; Tetraspanin-27; Tspan-27

基因别名: 4F9; C33; CD82; GR15; IA4; KAI1; R2; SAR2; ST6; TSPAN27

UniProt ID: (Human) P27701

Entrez Gene ID: (Human) 3732

功能

cell surface receptor signaling pathway

参与通路

protein binding