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Invitrogen
CD84 Polyclonal Antibody
高级验证
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
产品信息
PA5-64444
| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫组化 (IHC) |
1:5,000-1:10,000 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Recombinant protein corresponding to Human CD84 |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
0.2 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.2, with 40% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2639547 |
产品详细信息
Immunogen sequence: RRQGRIFPED AASKKTIYTY IMASRNTQPA ESRIYDEILQ SKVLPSKEEP VNTVYSEVQF ADKMGKASTQ DSKPPGTS
Highest antigen sequence identity to the following orthologs: Mouse - 51%, Rat - 53%.
靶标信息
CD84 is expressed on mature B cells and on B cell lines, including pre B cell lines, but not on plasma cell lines. Immunohistochemical studies demonstrated that CD84 strongly expressed on tissues macrophages. CD84 is also highly expressed on platelets and, at low levels on peripheral blood T cells. It is a highly glycosylated protein and belongs to immunoglobulin superfamily. It may play a role in leukocyte activation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD84; CD84 antigen (leukocyte antigen); Cell surface antigen MAX.3; DKFZp781E2378; Hly9-beta; leucocyte differentiation antigen CD84; leukocyte antigen CD84; Leukocyte differentiation antigen CD84; Signaling lymphocytic activation molecule 5; SLAM family member 5
基因别名: CD84; hCD84; LY9B; mCD84; SLAMF5
UniProt ID: (Human) Q9UIB8
Entrez Gene ID: (Human) 8832
分子生物学功能:
immunoglobulin receptor superfamily
adaptive immune response
defense response
homophilic cell adhesion via plasma membrane adhesion molecules
negative regulation of granulocyte macrophage colony-stimulating factor production
negative regulation of interleukin-18 production
negative regulation of mast cell activation
negative regulation of mast cell degranulation
innate immune response
leukocyte migration
regulation of store-operated calcium entry
