MA5-17897 targets CD94/KLRD1 in ELISA, FACS, and IF applications and shows reactivity with Mouse samples.
The MA5-17897 immunogen is mouse T cell clone AE7 cells.
Natural killer (NK) cells, like CD94, are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Three transcript variants encoding two different isoforms have been found for this gene.
Protein Aliases: CD94; Killer cell lectin-like receptor subfamily D member 1; natural killer cell receptor; Natural killer cells antigen CD94
Gene Aliases: CD94; Klrd1
UniProt ID: (Mouse) O54707
Entrez Gene ID: (Mouse) 16643