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Invitrogen
CDC25A Polyclonal Antibody
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产品信息
PA5-79014
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence at the N-terminus of human Cdc25A.
偶联物
形式
Lyophilized
浓度
500 µg/mL
保存条件
-20°C
运输条件
Wet ice
RRID
产品详细信息
The synthetic peptide sequence is 1-17aa, MELGPEPPHRRRLLFAC
Add 0.2 mL of distilled water, will yield a concentration of 500 µg/mL.
靶标信息
CDC25a is a member of the CDC25 family of phosphatases. Three CDC25 genes are present in human cells: CDC25A, CDC25B, and CDC25C. These three genes function at different phases of the cell cycle. CDC25a is required for progression through G1 and S phases of the cell cycle. CDC25a activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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