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Invitrogen
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Immunogen sequence: PKFRSDISEE LANVFYEDSD NESFCGFSES EVQDVLDHCG FLQKPRPDVT NELAGIFHAD SDDESFCGFS ESEIQDGM
Highest antigen sequence identity to the following orthologs: Mouse - 38%, Rat - 34%.
This gene was identified as a c-Myc responsive gene, and behaves as a direct c-Myc target gene. Overexpression of this gene is found to enhance the transformation of lymphoblastoid cells, and it complements a transformation-defective Myc Box II mutant, suggesting its involvement in c-Myc-mediated cell transformation. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.
仅用于科研。不用于诊断过程。未经明确授权不得转售。