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Positive Control: SH-SY5Y cell lysates, mouse hippocampus tissue lysates.
Subcellular Location: Cell membrane.
CDH10 is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is predominantly expressed in brain and is putatively involved in synaptic adhesions, axon outgrowth and guidance.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cadherin; cadherin 10 type 2; cadherin 10, type 2 (T2-cadherin); Cadherin-10; T2-cadherin
基因别名: A830016G23Rik; C030003B10Rik; C030011H18Rik; CDH10
UniProt ID: (Human) Q9Y6N8, (Mouse) P70408
Entrez Gene ID: (Human) 1008, (Mouse) 320873
分子生物学功能: cadherin