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Invitrogen
CDH12 Polyclonal Antibody
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产品信息
PA5-67791
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthesized peptide derived from human CDH12.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 0.87% NaCl, 30% glycerol
内含物
0.01% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Predicted to react with Mouse samples.
靶标信息
CDH12 is a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BR-cadherin; Brain cadherin; brain-cadherin; Cadherin; cadherin 12, type 2 (N-cadherin 2); cadherin, neural type, 2; Cadherin-12; N-cadherin 2; Neural type cadherin 2; neuronal cadherin 2
基因别名: CDH12; CDHB
UniProt ID: (Human) P55289, (Mouse) Q5RJH3
Entrez Gene ID: (Human) 1010, (Mouse) 215654
