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Proteintech
CDK5RAP1 Polyclonal Antibody
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产品信息
14740-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CDK5RAP1 Fusion Protein Ag6409 (239-587 aa encoded by BC050706)
偶联物
形式
Liquid
浓度
0.19 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MPVQTSASA TSAFVSIMRG CDNMCSYCIV PFTRGRERSR PIASILEEVK KLSEQGLKEV TLLGQNVNSF RDNSEVQFNS AVPTNLSRGF TTNYKTKQGG LRFAHLLDQV SRVDPEMRIR FTSPHPKDFP DEVLQLIHER DNICKQIHLP AQSGSSRVLE AMRRGYSREA YVELVHHIRE SIPGVSLSSD FIAGFCGETE EDHVQTVSLL REVQYNMGFL FAYSMRQKTR AYHRLKDDVP EEVKLRRLEE LITIFREEAT KANQTSVGCT QLVLVEGLSK RSATDLCGRN DGNLKVIFPD AEMEDVNNPG LRVRAQPGDY VLVKITSASS QTLRGHVLCR TTLRDSSAYC (239-587 aa encoded by BC050706)
靶标信息
Neuronal CDC2-like kinase, which is involved in the regulation of neuronal differentiation, is composed of a catalytic subunit, CDK5, and an activating subunit, p25NCK5A. The protein encoded by this gene binds to p25NCK5A and therefore may be involved in neuronal differentiation. Multiple transcript variants exist for this gene, but the full-length natures of only two have been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CDK5 activator-binding protein C42; CDK5 regulatory subunit-associated protein 1; CDK5RAP1.3; CDK5RAP1.4; Mitochondrial tRNA methylthiotransferase CDK5RAP1; mt-tRNA-2-methylthio-N6-dimethylallyladenosine synthase; mt-tRNA-N6-(dimethylallyl)adenosine(37) methylthiotransferase
基因别名: 2310066P17Rik; C20orf34; C42; CDK5RAP1; CGI-05; HSPC167
UniProt ID: (Human) Q9H859, (Rat) Q9JLH6, (Mouse) Q8BTW8
Entrez Gene ID: (Human) 51654, (Rat) 252827, (Mouse) 66971
brain development
tRNA methylthiolation
regulation of neuron differentiation
negative regulation of cyclin-dependent protein serine/threonine kinase activity
regulation of cyclin-dependent protein serine/threonine kinase activity
tRNA modification
cell proliferation
regulation of protein kinase activity
RNA modification
macromolecule modification
