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Invitrogen
CDK5RAP3 Polyclonal Antibody
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CDK5RAP3 Antibody (PA5-115000) in ICC/IF
Immunocytochemistry analysis of CDK5RAP3 in A549 cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115000). Secondary staining was applied with mouse anti-beta tubulin (1 hr at 37°, AlexaFluor 594 conjugated goat anti-rabbit IgG (Red), AlexaFluor 488 conjugated goat anti-mouse IgG (Green) and DAPI.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-115000
产品规格
种属反应
Human,
Mouse,
Non-human primate,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human CDK5RAP3(Accession Q96JB5), corresponding to amino acid residues G280-A330.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total CDK5RAP3.
靶标信息
This gene encodes a protein that has been reported to function in signaling pathways governing transcriptional regulation and cell cycle progression. It may play a role in tumorigenesis and metastasis. A pseudogene of this gene is located on the long arm of chromosome 20. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, May 2013].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CDK5 activator-binding protein C53; CDK5 activator-binding protein C53; CDK5 regulatory subunit-associated protein 3; IC53-2; LXXLL/leucine-zipper-containing ARF-binding protein; Protein HSF-27
基因别名: 1810007E24Rik; BC002318; C53; C81486; CDK5RAP3; HSF-27; IC53; LZAP; MST016; MSTP016; OK/SW-cl.114; PP1553
UniProt ID: (Mouse) Q99LM2
Entrez Gene ID: (Rat) 80278, (Mouse) 80280
regulation of cyclin-dependent protein serine/threonine kinase activity
regulation of mitotic cell cycle
brain development
cell proliferation
positive regulation of protein ubiquitination
negative regulation of NF-kappaB transcription factor activity
regulation of neuron differentiation
positive regulation of transcription from RNA polymerase II promoter
protein ufmylation
positive regulation of protein localization to nucleus
positive regulation of signal transduction by p53 class mediator
regulation of signal transduction involved in mitotic G2 DNA damage checkpoint
negative regulation of cellular protein catabolic process
positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
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