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Invitrogen
CDK7 Polyclonal Antibody
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产品信息
PA1-24252
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to a region of human CCNH.
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Recommended positive controls: Jurkat.
Predicted reactivity: Guinea Pig: 100%; Horse: 100%; Mouse: 83%; Rabbit: 83%; Rat: 83%.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The trimeric complex of CDK7, cyclin H and MNAT1, functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This complex is thought to serve as a direct link between the regulation of transcription and the cell cycle. The bound complex is important in the normal double-strand break repair function of breast cancer, type 1 (BRCA1). CDK7 may be a target of germline cancer-inducing mutations.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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