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Proteintech
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Immunogen sequence: NSYRGILNP SQPGQSSSSS QTFGVSSSGQ SVSSNQRPCS SDIPDSPCSG GPIVSHSGPY IPSSHSVSGG QRPVVVVVDQ HGSGAPGVVQ GPPCSNGGLP GKPCPPITSV DKSYGGYEVV GGSSDSYLVP GMTYSKGKIY PVGYFTKENP VKGSPGVPSF AAGPPISEGK YFSSNPIIPS QSAASSAIAF QPVGTGGVQL CGGGSTGSKG PCSPSSSRVP SSSSISGSSG LPYHPCGSAS QSPCSPPGTG SFSSSSSSQS SGKIILQPCG SKSSSSGHPC MSVSSLTLTG GPDGSPHPDP SAGAKPCGSS SAGKIPCRSI RDILA (180-503 aa encoded by BC031993)
This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Corneodesmosin; D6S586E; differentiated keratinocyte S protein; S protein
基因别名: AI747712; CDSN; HTSS; HTSS1; HYPT2; PSS; PSS1; S
UniProt ID: (Human) B0S7V2, (Mouse) Q7TPC1
Entrez Gene ID: (Human) 1041, (Mouse) 386463