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Invitrogen
CEACAM2 Monoclonal Antibody (935610)
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产品信息
MA5-62008
产品规格
种属反应
Mouse
宿主/亚型
Rat
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
935610
抗原
Mouse myeloma cell line NS0-derived recombinant mouse CEACAM-2, Gln35-Asp422
偶联物
形式
Lyophilized
浓度
0.5 mg/mL
纯化类型
Protein A/G
保存液
PBS with trehalose
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute at 0.5 mg/mL in sterile PBS.
靶标信息
CEACAM2 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 2) is a gene that encodes a protein belonging to the carcinoembryonic antigen (CEA) family, which is part of the immunoglobulin superfamily. CEACAM2 is involved in various cellular processes, including cell adhesion, intracellular signaling, and immune responses. It is expressed in several tissues, including the brain, liver, and epithelial cells of the gastrointestinal tract. CEACAM2 plays a role in maintaining tissue architecture and integrity by mediating cell-cell adhesion. It also participates in immune regulation by interacting with other cell surface molecules to modulate the activity of immune cells, such as macrophages and natural killer (NK) cells. Dysregulation or altered expression of CEACAM2 has been associated with various diseases, including cancer, where it can influence tumor progression and metastasis, and metabolic disorders, such as obesity and type 2 diabetes. Understanding the functions and mechanisms of CEACAM2 is crucial for developing therapeutic strategies aimed at targeting its role in disease processes. Research into CEACAM2 offers insights into its potential as a biomarker for disease diagnosis and prognosis, as well as a target for novel treatments in oncology and immunotherapy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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