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产品信息
PA5-51113
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthesized peptide derived from the Internal region of human Cerberus (aa 91-140).
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 0.5% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2636561
产品详细信息
Cerberus 1 Polyclonal Antibody detects endogenous levels of Cerberus 1 protein.
靶标信息
This gene encodes a cytokine member of the cysteine knot superfamily, characterized by nine conserved cysteines and a cysteine knot region. The cerberus-related cytokines, together with Dan and DRM/Gremlin, represent a group of bone morphogenetic protein antagonists that can bind directly to BMPs and inhibit their activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cerberus; cerberus 1, cysteine knot superfamily, homolog; cerberus-related 1; Cerberus-related protein; DAN domain family member 4; MGC119894; MGC119895; MGC96951
基因别名: CER1; DAND4; RGD1563046
UniProt ID: (Human) O95813
Entrez Gene ID: (Human) 9350, (Rat) 500485
ureteric bud development
growth plate cartilage chondrocyte proliferation
gastrulation
nervous system development
negative regulation of cell proliferation
anterior/posterior axis specification
anterior/posterior pattern specification
signal transduction involved in regulation of gene expression
negative regulation of Wnt signaling pathway
bone mineralization
BMP signaling pathway
negative regulation of BMP signaling pathway
negative regulation of activin receptor signaling pathway
sequestering of BMP in extracellular matrix
cell migration involved in gastrulation
determination of dorsal identity
determination of heart left/right asymmetry
cellular response to BMP stimulus
negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry
negative regulation of mesoderm development
