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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Sequence of this protein is as follows: EATFCDFPKI NHGILYDEEK YKPFSQVPTG EVFYYSCEYN FVSPSKSFWT RITCTEEGWS PTPKCLRLCF FPFVENGHSE SSGQTHLEGD TVQIICNTGY RLQNNENNIS CVERGWSTPP KCRSTDTSCV NPPTVQNAHI LSRQMSKYPS GERVRYECRS PYEMFGDEEV MCLNGNWTEP PQCKDSTGKC GPPPPIDNGD ITSFPLSVYA PASSVEYQCQ NLYQLEGNKR ITCRNGQWSE PPKCLHPCVI SREIMENYNI ALRWTAKQKL YLRTGESAEF VCKRGYRLSS RSHTLRTTCW DGKLEYPTCA KR
This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Complement factor H-related protein 1; FHL-1; FHR-1; H factor-like protein 1; H36
基因别名: CFHL; CFHL1; CFHL1P; CFHR1; CFHR1P; FHR1; HFL1; HFL2
Entrez Gene ID: (Human) 3078