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Invitrogen
CFHR1 Polyclonal Antibody
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产品信息
PA5-49704
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Fusion protein corresponding to a region derived from 22-330 amino acids of human complement factor H-related 1
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 40% glycerol
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody detects endogenous level of total CFHR1 protein.
靶标信息
This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: complement component factor h-like 1; complement factor H-related 1; complement factor H-related 1 pseudogene; complement factor H-related protein; Complement factor H-related protein 1; FHL-1; FHR-1; H factor (complement)-like 1; H factor (complement)-like 2; H factor-like protein 1; H-factor-like 1; H36
基因别名: AI194696; CFHL; CFHL1; CFHL1P; CFHR1; CFHR1P; CFHRB; FHR1; H36-1; H36-2; HFL1; HFL2
UniProt ID: (Human) Q03591
Entrez Gene ID: (Human) 3078, (Mouse) 50702
