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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: MGGTTSTRRV TFEADENENI TVVKGIRLSE NVIDRMKESS PSGSKSQRYS GAYGASVSDE ELKRRVAEEL ALEQAKKESE DQKRLKQAKE LDRERAAANE QLTRAILRER ICSEEERAKA KHLARQLEEK DRVLKKQDAF YKEQLARLEE RSSEFYRVTT EQYQKAAEEV EAKFKRYESH PVCADLQAKI LQCYRENTHQ TLKCSALATQ YMHCVNHAKQ SMLEKGG; Positive Samples: A-549, HeLa, A-431, Jurkat, HepG2, mouse kidney, mouse liver, rat heart, rat kidney, Mouse kidney, Mouse liver, Mouse heart; Cellular Location: Cytoplasm, Intermembrane side, Lipid-anchor, Mitochondrion, Mitochondrion inner membrane, Nucleus
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Has also been shown to function as a transcription factor which binds to the BAG1 promoter and represses BAG1 transcription. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Coiled-coil-helix-coiled-coil-helix domain-containing protein 3; coiled-coil-helix-coiled-coil-helix domain-containing protein 3, mitochondrial; FLJ20420; MICOS complex subunit Mic19
基因别名: 0610041L09Rik; 1700039J09Rik; AW558177; Chchd3; Mic19
UniProt ID: (Mouse) Q9CRB9
Entrez Gene ID: (Rat) 296966, (Mouse) 66075