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Immunogen sequence: EETHAPNSNW VYVMLPSKKT VRMPSVTQRL RDPDINPCLS ESDASTRCLD ENNYDRERCS TYFLRYKNCR RFWNSIVMQR RKNGVKPFMP
Highest antigen sequence identity to the following orthologs: Mouse - 63%, Rat - 63%.
CHCHD7 is a newly identified member of a multifamily of proteins containing a conserved (coiled coil 1)-(helix 1)-(coiled coil 2)-(helix 2) domain. Northern blot analysis revealed that the gene is ubiquitously expressed. Its biological function is unknown and the gene has hitherto not been associated with neoplasia. CHCHD7 and PLAG1 are located head-to-head about 500 bp apart in 8q12. A chromosomal aberration involving CHCHD7 is found in salivary gland pleiomorphic adenomas, the most common benign epithelial tumors of the salivary gland.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Coiled-coil-helix-coiled-coil-helix domain-containing protein 7; COX23 cytochrome c oxidase assembly homolog
基因别名: CHCHD7; COX23
UniProt ID: (Human) Q9BUK0
Entrez Gene ID: (Human) 79145
