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Proteintech
CHIA Polyclonal Antibody
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产品信息
21484-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CHIA Fusion Protein Ag15767 (109-476 aa encoded by BC036339)
偶联物
形式
Liquid
浓度
0.19 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MVSTPENRQ TFITSVIKFL RQYEFDGLDF DWEYPGSRGS PPQDKHLFTV LVQEMREAFE QEAKQINKPR LMVTAAVAAG ISNIQSGYEI PQLSQYLDYI HVMTYDLHGS WEGYTGENSP LYKYPTDTGS NAYLNVDYVM NYWKDNGAPA EKLIVGFPTY GHNFILSNPS NTGIGAPTSG AGPAGPYAKE SGIWAYYEIC TFLKNGATQG WDAPQEVPYA YQGNVWVGYD NIKSFDIKAQ WLKHNKFGGA MVWAIDLDDF TGTFCNQGKF PLISTLKKAL GLQSASCTAP AQPIEPITAA PSGSGNGSGS SSSGGSSGGS GFCAVRANGL YPVANNRNAF WHCVNGVTYQ QNCQAGLVFD TSCDCCNWA (109-476 aa encoded by BC036339)
靶标信息
CHIA degrades chitin and chitotriose. May participate in the defense against nematodes and other pathogens. There are 3 named isoforms produced by alternative splicing. CHIA is induced via a T helper-2 (Th2)-specific, interleukin-13-mediated pathway in epithelial cells and macrophages. CHIA may be an important mediator of IL13-induced responses in Th2-dominated disorders such as asthma. CHIA hydrolysis N-acetyl-beta-D-glucosaminide 1,4-beta-linkages in chitin and chitodextrins.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: acidic chitinase; Acidic mammalian chitinase; AMCase; eosinophil chemotactic cytokine; Lung-specific protein TSA1902; small acid mammalian chitinase; YNL
基因别名: 2200003E03Rik; AMCASE; CHIA; Chia1; CHIT2; TSA1902; YNL
UniProt ID: (Human) Q9BZP6, (Rat) Q6RY07, (Mouse) Q91XA9
Entrez Gene ID: (Human) 27159, (Rat) 113901, (Mouse) 81600
polysaccharide catabolic process
production of molecular mediator involved in inflammatory response
carbohydrate metabolic process
chitin metabolic process
chitin catabolic process
cell wall chitin metabolic process
apoptotic process
immune response
digestion
response to fungus
positive regulation of chemokine secretion
immune system process
inflammatory response
metabolic process
