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Invitrogen
CHMP4C Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-54889
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.2 mg/mL
规格
20 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MSKLGKFFKG GGSSKSRAAP SPQEALVRLR ETEEMLGKKQ EYLENRIQRE IALAKKHGTQ N
Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 84%.
靶标信息
CHMP4C belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A, is required for both MVB formation and regulation of cell cycle progression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: chromatin modifying protein 4C; chromatin-modifying protein 4c; hSnf7-3; hVps32-3; similar to yeast Snf7p; SNF7 homolog associated with Alix 3; Snf7 homologue associated with Alix 3; unnamed protein product; vacuolar protein sorting-associated protein 32-3; vps32-3
基因别名: Shax3; SNF7-3; VPS32C
UniProt ID: (Human) Q96CF2
Entrez Gene ID: (Human) 92421
plasma membrane repair
membrane budding
autophagy
nucleus organization
vacuolar transport
mitotic metaphase plate congression
regulation of centrosome duplication
macroautophagy
nuclear envelope reassembly
negative regulation of cytokinesis
endosome transport via multivesicular body sorting pathway
late endosome to vacuole transport via multivesicular body sorting pathway
multivesicular body assembly
viral budding via host ESCRT complex
ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
mitotic cytokinesis checkpoint
viral budding from plasma membrane
vesicle fusion with vacuole
multivesicular body-lysosome fusion
midbody abscission
multivesicular body sorting pathway
membrane fission
autophagosome maturation
regulation of mitotic spindle assembly
late endosome to lysosome transport
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
