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Invitrogen
CHRM4 Polyclonal Antibody
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产品信息
PA5-33433
产品规格
种属反应
Bovine,
Horse,
Guinea pig,
Hamster,
Human,
Mouse,
Pig,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic 20 amino acid peptide from 3rd cytoplasmic domain of human CHRM4.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Percent identity with other species by BLAST analysis: Human, Gorilla, Mouse, Rat, Bovine, Hamster, Horse, Pig, Guinea pig (100%) Dog, Elephant, Panda (95%) Bat (90%).
靶标信息
Muscarinic acetylcholine receptor M4 is an Acetylcholine Receptor. Unlike muscarinic receptor M2, the M4 receptor is not involved in smooth muscle contraction. The clinical relevance of this receptor is unknown. However, mouse studies have linked it to adenylyl cyclase inhibition. Muscarinic acetylcholine receptor M4 has been reported to be expressed in many regions of the rat brain, particularly the striatum and hippocampus. ESTs have been isolated from human breast and eye libraries.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: acetylcholine receptor; acetylcholine receptor, muscarinic 4; acetylcholinergic receptor M4; AChR M4; cholinergic receptor; cholinergic receptor, muscarin 4; cholinergic receptor, muscarinic 4; Mm4 mAChR; muscarinic acetylcholine receptor 4; Muscarinic acetylcholine receptor M4; muscarinic receptor 4; muscarinic receptor, M4 subtype
基因别名: acm4; Chrm-4; CHRM4; GPM4; HM4; I79_002865; M4; M4R
UniProt ID: (Human) P08173, (Mouse) P32211, (Rat) P08485
G-protein coupled acetylcholine receptor signaling pathway
regulation of locomotion
signal transduction
cell surface receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway
phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
synaptic transmission, cholinergic
cell proliferation
positive regulation of GTPase activity
G-protein coupled receptor signaling pathway
chemical synaptic transmission
sensory perception of chemical stimulus
response to organic substance
