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Invitrogen
CHRNA3 (extracellular) Polyclonal Antibody
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CHRNA3 (extracellular) Antibody (PA5-77501) in IHC (F)
Immunohistochemistry analysis of CHRNA3 (extracellular) in immersion-fixed, free floating frozen rat brain. A) Samples were probed with CHRNA3 (extracellular) polyclonal antibody (Product # PA5-77501) using a dilution of 1:200, and incubated with parvalbumin (red) (green). B) Apical dendrites (thin arrows). A few cortical interneurons (thick arrow).
产品信息
PA5-77501
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide (C)KWKPSDYQGVEFMR, corresponding to amino acid residues 91-104 of rat nAChRalpha3
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
保存条件
-20°C
运输条件
Wet ice
RRID
产品详细信息
Product is shipped at room temperature as a lyophilized powder and should be stored at -20 °C upon receipt. Reconstitution: add 50 µL of deionized water.
靶标信息
CHRNA3 locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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