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Invitrogen
CHRNA7 (extracellular) Polyclonal Antibody
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CHRNA7 (extracellular) Antibody (PA5-77505) in IHC (F)
Immunohistochemistry analysis of CHRNA7 (extracellular) in frozen rat dorsal root ganglion. Samples were probed with CHRNA7 (extracellular) polyclonal antibody (Product # PA5-77505) using a dilution of 1:200, and incubated with Hoechst.
产品信息
PA5-77505
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide (C)KELVKNYNPLER, corresponding to amino acid residues 31-42 of rat nAChRalpha7
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
保存条件
-20°C
运输条件
Wet ice
RRID
产品详细信息
Product is shipped at room temperature as a lyophilized powder and should be stored at -20 °C upon receipt. Reconstitution: add 50 µL of deionized water.
靶标信息
Chromosome 15 encodes over 700 genes and comprises nearly 3% of the human genome. CHRFAM7A, a fusion protein comprised of FAM7A and AChR alpha7, is encoded by the CHRFAM7A gene, which is located on a region of human chromosome 15 that is associated with several neuropsychiatric disorders, such as schizophrenia and bipolar affective disorder. CHRFAM7A, also known as D-10 or CHRNA7, is a 412 amino acid multi-pass membrane protein that belongs to the nicotinic acetylcholine receptor (nAChR) subfamily of ligand-gated ion channel proteins, a protein superfamily that mediates signal transmission at synapses. CHRFAM7A is expressed in the hippocampus. Alternative splicing of the CHRFAM7A gene produces two splice variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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