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Bioss

CHRNB Polyclonal Antibody

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说明书
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产品信息

BS-4247R

应用
建议稀释比
已发表文章

免疫印迹 (WB)

1:500
-

免疫组化（石蜡） (IHC (P))

1:200
-

免疫组化（冰冻） (IHC (F))

1:100-1:500
-

免疫细胞化学 (ICC/IF)

1:50-1:200
-

酶联免疫吸附实验 (ELISA)

1:500-1:1,000
-
产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

KLH conjugated synthetic peptide derived from human CHRNB2.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

规格

100 µg

纯化类型

Protein A

保存液

0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

内含物

0.02% ProClin 300

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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Cite this product

生物信息学

蛋白别名: acetylcholine receptor beta 2 neural; Acetylcholine receptor beta 4; acetylcholine receptor, nicotinic, beta 2 (neuronal); acetylcholine receptor, nicotinic, beta 4 (neuronal); beta2 human neuronal nicotinic acetylcholine receptor; cholinergic receptor nicotinic beta polypeptide 2; cholinergic receptor, nicotinic beta 2; cholinergic receptor, nicotinic beta 4; cholinergic receptor, nicotinic, beta 2 (neuronal); cholinergic receptor, nicotinic, beta 4 (neuronal); cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal); cholinergic receptor, nicotinic, beta polypeptide 4; cholinergic receptor, nicotinic, beta subunit 2; N-alpha 1; N-alpha 2; neuronal acetylcholine receptor non-alpha-1 chain; neuronal acetylcholine receptor non-alpha-2 chain; neuronal nicotinic acetylcholine receptor beta 2; neuronal nicotinic receptor beta 4 subunit; neurotransmitter receptor subunit; nicotinic acetylcholine receptor beta4 subunit; nicotinic acetylcholine receptor-related protein; unnamed protein product

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基因别名: [b]2-nAchR; Acrb-2; Acrb-4; Acrb2; Acrb4; C030030P04Rik; EFNL3; nAChRB2

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UniProt ID: (Human) P17787, (Human) P30926, (Rat) P12390, (Mouse) Q9ERK7, (Mouse) Q8R493, (Rat) P12392

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Entrez Gene ID: (Human) 1141, (Human) 1143, (Rat) 54239, (Mouse) 11444, (Mouse) 108015, (Rat) 25103

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功能
transmembrane signaling receptor activity ion channel activity extracellular ligand-gated ion channel activity protein binding ligand-gated ion channel activity acetylcholine receptor activity acetylcholine-gated cation channel activity acetylcholine binding transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential macromolecular complex binding quaternary ammonium group binding heterocyclic compound binding
参与通路
ion transport calcium ion transport signal transduction synaptic transmission, cholinergic regulation of appetite ion transmembrane transport regulation of neurotransmitter secretion membrane depolarization positive regulation of transmission of nerve impulse regulation of postsynaptic membrane potential excitatory postsynaptic potential synaptic transmission involved in micturition acetylcholine receptor signaling pathway chemical synaptic transmission, postsynaptic response to acetylcholine action potential smooth muscle contraction regulation of smooth muscle contraction locomotory behavior response to nicotine behavioral response to nicotine regulation of membrane potential conditioned taste aversion response to hypoxia visual perception sensory perception of sound learning memory associative learning visual learning regulation of dopamine secretion sensory perception of pain vestibulocochlear nerve development optic nerve morphogenesis lateral geniculate nucleus development central nervous system projection neuron axonogenesis central nervous system neuron axonogenesis positive regulation of B cell proliferation regulation of synaptic transmission, dopaminergic positive regulation of synaptic transmission, dopaminergic positive regulation of dopamine secretion social behavior regulation of dopamine metabolic process B cell activation response to cocaine regulation of circadian sleep/wake cycle, REM sleep regulation of circadian sleep/wake cycle, non-REM sleep response to ethanol negative regulation of action potential regulation of dendrite morphogenesis neurological system process cognition regulation of synapse assembly presynaptic modulation of chemical synaptic transmission
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