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Invitrogen
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Immunogen sequence: LSVVVLNLHH RSPHTHQMPL WVRQIFIHKL PLYLRLKRPK PERDLMPEPP HCSSPGSGWG RGTDEYFIRK PPSDFLFPKP NRFQPELSAP DLRRFIDGPN RAVALLPELR EVVSSISYIA RQLQEQEDHD ALKEDWQF
Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 86%.
The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。