The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome.
蛋白别名: acetylcholine receptor; Acetylcholine receptor beta; Acetylcholine receptor subunit beta; acetylcholine receptor, nicotinic, beta 1 (muscle); AChR beta; cholinergic receptor; cholinergic receptor nicotinic beta polypeptide 1; cholinergic receptor, nicotinic beta 1; cholinergic receptor, nicotinic, beta 1 (muscle); cholinergic receptor, nicotinic, beta polypeptide 1 (muscle); Chrnb 1; nAChRB1
基因别名: Achr-2; ACHRB; Acrb; CHRNB; CHRNB1; CMS1D; CMS2A; CMS2C; RNACRB1; SCCMS
分子生物学功能: ligand-gated ion channel