FIGURE: 1 / 1
Antigen Affinity Purified from Pooled Serum
Neuronal acetylcholine receptors are homo- or heteropentameric complexes composed of homologous alpha and beta subunits. They belong to a superfamily of ligand-gated ion channels which allow the flow of sodium and potassium across the plasma membrane in response to ligands such as acetylcholine and nicotine. This gene encodes one of several beta subunits. Mutations in this gene are associated with autosomal dominant nocturnal frontal lobe epilepsy.
Protein Aliases: acetylcholine receptor; acetylcholine receptor beta 2 neural; cholinergic receptor; cholinergic receptor nicotinic beta polypeptide 2; cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal); cholinergic receptor, nicotinic, beta subunit 2; N-alpha 1; Neuronal acetylcholine receptor non-alpha-1 chain; Neuronal acetylcholine receptor subunit beta-2
Gene Aliases: [b]2-nAchR; Acrb-2; Acrb2; C030030P04Rik; Chrnb2
Molecular Function: ligand-gated ion channel