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Product Details
PA5-95642
产品规格
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
Immunogen
Fusion protein from the cytoplasmic loop of the beta 2 subunit of rat nAChR
Conjugate
Unconjugated
形式
liquid
浓度
0.15 mg/mL
纯化类型
Antigen Affinity Chromatography
保存液
10mM HEPES, pH 7.5, with 100µg/mL BSA, 50% glycerol, 0.15M NaCl
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
RRID
AB_2807444
Product Specific Information
Antigen Affinity Purified from Pooled Serum
Target Information
Neuronal acetylcholine receptors are homo- or heteropentameric complexes composed of homologous alpha and beta subunits. They belong to a superfamily of ligand-gated ion channels which allow the flow of sodium and potassium across the plasma membrane in response to ligands such as acetylcholine and nicotine. This gene encodes one of several beta subunits. Mutations in this gene are associated with autosomal dominant nocturnal frontal lobe epilepsy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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Bioinformatics
Protein Aliases: acetylcholine receptor; acetylcholine receptor beta 2 neural; cholinergic receptor; cholinergic receptor nicotinic beta polypeptide 2; cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal); cholinergic receptor, nicotinic, beta subunit 2; N-alpha 1; Neuronal acetylcholine receptor non-alpha-1 chain; Neuronal acetylcholine receptor subunit beta-2
Gene Aliases: [b]2-nAchR; Acrb-2; Acrb2; C030030P04Rik; Chrnb2
UniProt ID: (Rat) P12390, (Mouse) Q9ERK7
Entrez Gene ID: (Rat) 54239, (Mouse) 11444
Molecular Function:
ligand-gated ion channel
action potential
conditioned taste aversion
response to hypoxia
calcium ion transport
smooth muscle contraction
signal transduction
synaptic transmission, cholinergic
visual perception
sensory perception of sound
learning
memory
locomotory behavior
associative learning
visual learning
regulation of dopamine secretion
sensory perception of pain
vestibulocochlear nerve development
optic nerve morphogenesis
lateral geniculate nucleus development
central nervous system projection neuron axonogenesis
central nervous system neuron axonogenesis
positive regulation of B cell proliferation
regulation of synaptic transmission, dopaminergic
positive regulation of synaptic transmission, dopaminergic
positive regulation of dopamine secretion
response to nicotine
behavioral response to nicotine
social behavior
regulation of dopamine metabolic process
B cell activation
response to cocaine
regulation of circadian sleep/wake cycle, REM sleep
regulation of membrane potential
regulation of circadian sleep/wake cycle, non-REM sleep
response to ethanol
negative regulation of action potential
regulation of dendrite morphogenesis
neurological system process
cognition
protein heterooligomerization
membrane depolarization
regulation of synapse assembly
synaptic transmission involved in micturition
cation transmembrane transport
transport
ion transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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