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产品信息
MA5-31692
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
2D12A2
抗原
Purified recombinant fragment of human CHRNB2 (AA: extra 26-233) expressed in E. coli.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2787316
产品详细信息
MA5-31692 has been tested in indirect ELISA.
靶标信息
Neuronal acetylcholine receptors are homo- or heteropentameric complexes composed of homologous alpha and beta subunits. They belong to a superfamily of ligand-gated ion channels which allow the flow of sodium and potassium across the plasma membrane in response to ligands such as acetylcholine and nicotine. This gene encodes one of several beta subunits. Mutations in this gene are associated with autosomal dominant nocturnal frontal lobe epilepsy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: acetylcholine receptor; acetylcholine receptor, nicotinic, beta 2 (neuronal); beta2 human neuronal nicotinic acetylcholine receptor; cholinergic receptor; cholinergic receptor, nicotinic beta 2; cholinergic receptor, nicotinic, beta 2 (neuronal); cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal); Neuronal acetylcholine receptor subunit beta-2; neuronal nicotinic acetylcholine receptor beta 2
基因别名: CHRNB2; EFNL3; nAChRB2
UniProt ID: (Human) P17787
Entrez Gene ID: (Human) 1141
action potential
conditioned taste aversion
response to hypoxia
ion transport
calcium ion transport
smooth muscle contraction
signal transduction
synaptic transmission, cholinergic
neuromuscular synaptic transmission
visual perception
sensory perception of sound
learning
memory
locomotory behavior
associative learning
visual learning
regulation of dopamine secretion
sensory perception of pain
vestibulocochlear nerve development
optic nerve morphogenesis
lateral geniculate nucleus development
central nervous system projection neuron axonogenesis
positive regulation of B cell proliferation
regulation of synaptic transmission, dopaminergic
positive regulation of synaptic transmission, dopaminergic
positive regulation of dopamine secretion
response to nicotine
behavioral response to nicotine
social behavior
regulation of dopamine metabolic process
B cell activation
response to cocaine
regulation of circadian sleep/wake cycle, REM sleep
regulation of circadian sleep/wake cycle, non-REM sleep
response to ethanol
negative regulation of action potential
regulation of dendrite morphogenesis
neurological system process
cognition
protein heterooligomerization
membrane depolarization
regulation of synapse assembly
synaptic transmission involved in micturition
cation transmembrane transport
