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CHST11 Antibody (PA5-89396) in WB
Western blot analysis of CHST11 in extracts of various cell lines. Samples were incubated with CHST11 Polyclonal antibody (Product # PA5-89396) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-89396
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 38-352 of human CHST11 (NP_0608831)
偶联物
形式
Liquid
浓度
0.52 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2805544
产品详细信息
Immunogen sequence: HPVMRRNPFG VDICCRKGSR SPLQELYNPI QLELSNTAVL HQMRRDQVTD TCRANSATSR KRRVLTPNDL KHLVVDEDHE LIYCYVPKVA CTNWKRLMMV LTGRGKYSDP MEIPANEAHV SANLKTLNQY SIPEINHRLK SYMKFLFVRE PFERLVSAYR NKFTQKYNIS FHKRYGTKII KRQRKNATQE ALRKGDDVKF EEFVAYLIDP HTQREEPFNE HWQTVYSLCH PCHIHYDLVG KYETLEEDSN YVLQLAGVGS YLKFPTYAKS TRTTDEMTTE FFQNISSEHQ TQLYEVYKLD FLMFNYSVPS YLKLE; Positive Samples: Raji, Rat brain; Cellular Location: Golgi apparatus membrane, Single-pass type II membrane protein
靶标信息
Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Can also sulfate Gal residues in desulfated dermatan sulfate. Preferentially sulfates in GlcA->GalNAc unit than in IdoA->GalNAc unit. Does not form 4, 6- di-O-sulfated GalNAc when chondroitin sulfate C is used as an acceptor.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C4S-1; C4ST; C4ST-1; Carbohydrate sulfotransferase 11; Chondroitin 4-O-sulfotransferase 1; Chondroitin 4-sulfotransferase 1; IgH/CHST11 fusion
基因别名: C4ST; C4ST-1; C4ST1; CHST11; HSA269537
UniProt ID: (Human) Q9NPF2, (Rat) P69478
Entrez Gene ID: (Human) 50515, (Rat) 314694
chondrocyte development
respiratory gaseous exchange
post-embryonic development
carbohydrate biosynthetic process
chondroitin sulfate biosynthetic process
negative regulation of transforming growth factor beta receptor signaling pathway
polysaccharide localization
post-anal tail morphogenesis
regulation of cell proliferation
embryonic digit morphogenesis
negative regulation of apoptotic process
developmental growth
embryonic viscerocranium morphogenesis
chondroitin sulfate metabolic process
embryonic limb morphogenesis
embryonic skeletal system morphogenesis
cartilage development
