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Invitrogen
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Immunogen sequence: YKHESKLVLR KLQQHQAGEY FCKAQSDAGA VKSKVAQLIV TASDETPCNP VPESYLIRLP HDCFQNATNS FYYDVGRCPV KTCAGQQDNG IRCRDAVQNC CGISKTEERE IQCSGYTLPT K
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 89%.
Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. This gene encodes the cartilage intermediate layer protein activity. The full-length and the N-terminal domain of this protein was shown to function as an IGF-1 antagonist. An allelic variant of this gene has been associated with lumbar disc disease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。