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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: MEKSEPVDQR RHTAGKAIVD SRSAQPKETS EERKARLSEW KAGKGRVLKR PPNSVVTQHE PAGQNEKPVG SFWTTMAEED EQRLFTEKVN NTFSECLNLI NEGCPKEDIL VTLNDLIKNI PDAKKLVKYW ICLALIEPIT SPIENIIAIY EKAILAGAQV R
Nedd4-binding partner-1 (N4BP1) is a developmentally expressed protein interactor and monoubiquitylation substrate of Nedd4, a HECT domain-containing ubiquitin ligase that mediates ubiquitylation and proteasome degradation of target proteins and may have a fundamental role to play in embryonic processes. N4BP1 can undergo Nedd4-mediated polyubiquitylation and proteosomal degradation. N4BP1 also functions as a negative regulator of AIF4 (also known as ITCH or Atrophin-1), an E3-ubiquitin ligase, by interacting with the second WW domain of AIF4 and impairing ubiquitination of substrates.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CTCL tumor antigen se20-10; Cytoskeleton-associated protein 2; Tumor- and microtubule-associated protein
基因别名: CKAP2; LB1; TMAP
Entrez Gene ID: (Human) 26586