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产品信息
PA5-41034
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the C-terminal of human CLCA2
偶联物
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
RRID
AB_2576483
产品详细信息
Peptide sequence: RYFFSFAANG RYSLKVHVNH SPSISTPAHS IPGSHAMYVP GYTANGNIQM
Sequence homology: Cow: 100%; Dog: 85%; Horse: 85%; Human: 100%; Mouse: 79%; Pig: 77%; Rabbit: 92%; Rat: 93%
靶标信息
The protein encoded by this gene belongs to the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same site on chromosome 1p31-p22 and share high degrees of homology in size, sequence and predicted structure, but differ significantly in their tissue distributions. Since this protein is expressed predominantly in trachea and lung, it is suggested to play a role in the complex pathogenesis of cystic fibrosis. It may also serve as adhesion molecule for lung metastatic cancer cells, mediating vascular arrest and colonization, and furthermore, it has been implicated to act as a tumor suppressor gene for breast cancer.
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生物信息学
蛋白别名: CaCC-3; Calcium-activated chloride channel family member 2; Calcium-activated chloride channel protein 3; Calcium-activated chloride channel regulator 2; Calcium-activated chloride channel regulator 2, 109 kDa form; Calcium-activated chloride channel regulator 2, 35 kDa form; calcium-activated chloride channel-2; chloride channel regulator 2; chloride channel, calcium activated, family member 2; CLCA family member 2, chloride channel regulator; FLJ97885; hCaCC-3; hCLCA2
基因别名: CACC; CaCC-3; CACC3; CLCA2; CLCRG2
UniProt ID: (Human) Q9UQC9
Entrez Gene ID: (Human) 9635
分子生物学功能:
ion channel
