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Invitrogen
CLCA2 Polyclonal Antibody
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CLCA2 Antibody (PA5-61462)
Relative expression in different tissues in IHC: Detection of differential expression levels of CLCA2 demonstrates antibody specificity. Immunohistochemical analysis of CLCA2 using anti-CLCA2 Polyclonal Antibody (Product # PA5-61462), shows significant staining of CLCA2 in human esophagus and shows minimal or weak staining in human stomach tissues. The relative expression levels of CLCA2 within each tissue... View More
产品信息
PA5-61462
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human CLCA2
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: EELTLSWTAP GEDFDQGQAT SYEIRMSKSL QNIQDDFNNA ILVNTSKRNP QQAGIREIFT FSPQISTNGP EHQPNGETHE SHRIYVAIRA MDRNSLQSAV SNIAQAPLFI PPNSDPVPAR DYLILKGVLT AMGL
Highest antigen sequence identity to the following orthologs: Mouse - 63%, Rat - 66%.
靶标信息
The protein encoded by this gene belongs to the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same site on chromosome 1p31-p22 and share high degrees of homology in size, sequence and predicted structure, but differ significantly in their tissue distributions. Since this protein is expressed predominantly in trachea and lung, it is suggested to play a role in the complex pathogenesis of cystic fibrosis. It may also serve as adhesion molecule for lung metastatic cancer cells, mediating vascular arrest and colonization, and furthermore, it has been implicated to act as a tumor suppressor gene for breast cancer.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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