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Invitrogen
CLN5 Polyclonal Antibody
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CLN5 Antibody (PA5-88837) in IHC (P)
Immunohistochemistry analysis of CLN5 in paraffin-embedded human appendix. Samples were incubated with CLN5 Polyclonal antibody (Product # PA5-88837) using a dilution of 1:150 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
产品信息
PA5-88837
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 47-358 of human CLN5 (NP_006484.2).
偶联物
形式
Liquid
浓度
2.8 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: IPSRRHWPVP YKRFDFRPKP DPYCQAKYTF CPTGSPIPVM EGDDDIEVFR LQAPVWEFKY GDLLGHLKIM HDAIGFRSTL TGKNYTMEWY ELFQLGNCTF PHLRPEMDAP FWCNQGAACF FEGIDDVHWK ENGTLVQVAT ISGNMFNQMA KWVKQDNETG IYYETWNVKA SPEKGAETWF DSYDCSKFVL RTFNKLAEFG AEFKNIETNY TRIFLYSGEP TYLGNETSVF GPTGNKTLGL AIKRFYYPFK PHLPTKEFLL SLLQIFDAVI VHKQFYLFYN FEYWFLPMKF PFIKITYEEI PLPIRNKTLS GL; Positive Samples: Mouse heart, Rat heart; Cellular Location: Lysosome
靶标信息
This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.[provided by RefSeq, Oct 2008].
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Bis(monoacylglycero)phosphate synthase CLN5; BMP synthase CLN5; ceroid-lipofuscinosis; Ceroid-lipofuscinosis neuronal protein 5; ceroid-lipofuscinosis neuronal protein 5 homolog; Palmitoyl protein thioesterase CLN5; Protein CLN5; S-depalmitoylase CLN5
基因别名: A730075N08Rik; BMPS; CLN5; NCL
UniProt ID: (Human) O75503, (Mouse) Q3UMW8
Entrez Gene ID: (Human) 1203, (Rat) 306128, (Mouse) 211286
