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CLYBL, also named as CLB, is a Mitochondrial citramalyl-CoA lyase indirectly involved in the vitamin B12 metabolism. It is a human mitochondrial enzyme of unknown function that is found in multiple eukaryotic taxa and conserved to bacteria. It acts as a beta-methylmalate synthase in vitro, by mediating conversion of glyoxylate and propionyl-CoA to beta-methylmalate. There are two isoforms with MW 31-33 kDa and 35-37 kDa.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: (3S)-malyl-CoA thioesterase; bA134O15.1; Beta-methylmalate synthase; Citramalyl-CoA lyase, mitochondrial; Citrate lyase beta-like; Citrate lyase subunit beta-like protein; Citrate lyase subunit beta-like protein, mitochondrial; Malate synthase
基因别名: 0610033J05Rik; 2310014M14Rik; AI256068; CLB; CLYBL
UniProt ID: (Human) Q8N0X4, (Mouse) Q8R4N0
Entrez Gene ID: (Human) 171425, (Mouse) 69634