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Invitrogen
CNGA3 Monoclonal Antibody (CNC 9C1)
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CNGA3 Antibody (MA3-901) in ICC/IF
Immunofluorescent analysis using CNGA3 Monoclonal Antibody (CNC 9C1) (Product # MA3-901) shows CNGA3 staining in B-3 Cells (green). F-Actin staining with Phalloidin (red) and nuclei with DAPI (blue) is shown. Cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were probed without (control) or with an antibody recognizing CNGA3 (Product # MA3-901) at a dilution of 1:20 over night at 4°C, washed with PBS and incubated with a DyLight-488 conjugated secondary antibody (Product # 35503, Goat Anti-Mouse). Imag... View More
产品信息
MA3-901
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
CNC 9C1
抗原
MBP-fusion protein of the C-terminal region of the rat a2 subunit (amino acids K581-D670)
偶联物
形式
Liquid
浓度
Conc. Not Determined
保存液
ascites
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
MA3-901 detects CNG channel from human, mouse and rat samples.
MA3-901 has been successfully used in Western blotting and immunohistochemistry procedures. By Western blot MA3-901 detects a band representing CNG channel. MA3-901 is specific to the a2 subunit of the CNG channel.
The MA3-901 immunogen is a MBP-fusion protein of the C-terminal region of the rat a2 subunit (amino acids K581-D670)
靶标信息
This gene encodes a member of the cyclic nucleotide-gated cation channel protein family which is required for normal vision and olfactory signal transduction. Mutations in this gene are associated with achromatopsia (rod monochromacy) and color blindness. Two alternatively spliced transcripts encoding different isoforms have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: cng channel; CNG channel alpha-3; CNG-3; CNGalpha2; CNGgust; cone photoreceptor cGMP-gated channel alpha subunit; cone photoreceptor cGMP-gated channel subunit alpha; Cone photoreceptor cGMP-gated channel subunit alpha-3; cyclic nucleotide-gated cation channel alpha-3; Cyclic nucleotide-gated channel alpha-3; Gustatory cyclic nucleotide-gated cation channel
基因别名: ACHM2; CCNC1; CCNCa; CCNCalpha; CNCG3; CNG3; CNGA3
UniProt ID: (Human) Q16281, (Mouse) Q9JJZ8
Entrez Gene ID: (Human) 1261, (Mouse) 12790, (Rat) 85257
intracellular cAMP activated cation channel activity
intracellular cGMP activated cation channel activity
voltage-gated potassium channel activity
protein C-terminus binding
ligand-gated ion channel activity
cGMP binding
nucleotide binding
ion channel activity
intracellular cyclic nucleotide activated cation channel activity
protein binding
signal transducer activity
ligand-gated ion channel
transport
cation transport
signal transduction
visual perception
response to corticosteroid
response to magnesium ion
regulation of membrane potential
response to cAMP
potassium ion transmembrane transport
ion transport
ion transmembrane transport
regulation of ion transmembrane transport
retinal cone cell development
response to stimulus
transmembrane transport
cation transmembrane transport
phototransduction, visible light
