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Invitrogen
CNGB3 Polyclonal Antibody
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产品信息
PA5-66068
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human CNGB3
偶联物
形式
Liquid
浓度
0.2 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: NPDPQNAAEPT GTVPEQKEMD PGKEGPNSPQ NKPPAAPVIN EYADAQLHNL VKRMRQRTAL YKKKLVEGDL SSPEASPQTA KPTAVPPVKE SDDKPTEHYY RLLWFKVKKM PLTEYLKRIK LPNS
Highest antigen sequence identity to the following orthologs - mouse 47%, rat 46%.
靶标信息
Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cGMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficiency of the channel when coexpressed with CNGA3. Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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