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Invitrogen
CNTF Polyclonal Antibody
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产品信息
PA1-24826
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant, full length rat CNTF protein, expressed in E. coli.
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
PA1-24826 detects CNTF from rat samples. PA1-24826 is expected to cross react with human (85% conserved) and rabbit (85% conserved) due to sequence homology.
PA1-24826 has been successfully used in neutralization, inhibition assays, and Western blot procedures. Neutralization: The ND50 is 80 ug/ml.
The PA1-24826 immunogen is recombinant, full length rat CNTF protein, expressed in E. coli.
靶标信息
The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of ZFP91 and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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