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Invitrogen
COL4A2 Polyclonal Antibody
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COL4A2 Antibody (PA5-79058) in IHC (P)
Immunohistochemistry (Paraffin) analysis of COL4A2 in paraffin-embedded section of human breast cancer tissue using COL4A2 Polyclonal Antibody (Product # PA5-79058). Heat mediated antigen retrieval was performed in EDTA buffer (pH 8.0, epitope retrieval solution). The tissue section was blocked with 10% goat serum. The tissue section was then incubated with the primary antibody at a 2 µg/mL dilution overnig... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-79058
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence at the C-terminus of human Canstatin (1697-1712aa LIRTHISRCQVCMKNL).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
500 µg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
no preservative
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human placenta tissue. IHC: human breast cancer tissue, human breast cancer tissue, human placenta tissue.
靶标信息
Collagen IV is a major constituent of the basement membranes along with laminins and enactins. Collagen IV is composed of alpha 1 IV chain and alpha 2 IV chain in 2:1 ratio. Collagen IV can form insoluble fibers with high tensile strength. Antibody to collagen IV is useful in detecting the loss of parts of basement membrane in carcinomas.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: a matrix-derived inhibitor of angiogenesis and tumor growth; canstatin; COL4A2 NC1 domain; collagen alpha-2 type IV; matrix-derived inhibitor of angiogenesis and tumor growth; unnamed protein product
基因别名: BSVD2; BSVD2A; BSVD2B; ICH; POREN2
UniProt ID: (Human) P08572
Entrez Gene ID: (Human) 1284
transcription, DNA-templated
response to activity
negative regulation of angiogenesis
extracellular matrix organization
collagen fibril organization
endodermal cell differentiation
collagen-activated tyrosine kinase receptor signaling pathway
cellular response to transforming growth factor beta stimulus
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
