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The antibody detects endogenous levels of total COLEC11 protein.
This gene encodes a member of the collectin family of C-type lectins that possess collagen-like sequences and carbohydrate recognition domains. Collectins are secreted proteins that play important roles in the innate immune system by binding to carbohydrate antigens on microorganisms, facilitating their recognition and removal. The encoded protein binds to multiple sugars with a preference for fucose and mannose. Mutations in this gene are a cause of 3MC syndrome-2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CL-K1; Collectin 11; Collectin K1; Collectin kidney protein 1; collectin sub-family member 11; Collectin-11; Collectin11
基因别名: 3MC2; CL-K1-I; CL-K1-II; CL-K1-IIa; CL-K1-IIb; CLK1; COLEC11; UNQ596/PRO1182
UniProt ID: (Human) Q9BWP8
Entrez Gene ID: (Human) 78989
分子生物学功能: surfactant